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Brain
Differential Diagnosis
Scalp, Skull
Clinically Based Differentials
Macrocephaly
Macrocephaly
Chang Yueh Ho, MD; Susan I. Blaser, MD, FRCPC
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DIFFERENTIAL DIAGNOSIS

    ESSENTIAL INFORMATION

    • Key Differential Diagnosis Issues

      • Helpful Clues for Common Diagnoses

        • Helpful Clues for Less Common Diagnoses

          • Helpful Clues for Rare Diagnoses

            Selected References

            1. Libero LE et al: Persistence of megalencephaly in a subgroup of young boys with autism spectrum disorder. Autism Res. 9(11):1169-1182, 2016
            2. Radoš M et al: Volumetric analysis of cerebrospinal fluid and brain parenchyma in a patient with hydranencephaly and macrocephaly--case report. Croat Med J. 55(4):388-93, 2014
            3. Colombani M et al: A new case of megalencephaly and perisylvian polymicrogyria with post-axial polydactyly and hydrocephalus: MPPH syndrome. Eur J Med Genet. 49(6):466-71, 2006
            4. Groeschel S et al: Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces. Pediatr Neurol. 34(1):35-40, 2006
            5. D'Ambrosio AL et al: Villous hypertrophy versus choroid plexus papilloma: a case report demonstrating a diagnostic role for the proliferation index. Pediatr Neurosurg. 39(2):91-6, 2003
            6. Medina LS et al: Children with macrocrania: clinical and imaging predictors of disorders requiring surgery. AJNR Am J Neuroradiol. 22(3):564-70, 2001
            7. Wilms G et al: CT and MR in infants with pericerebral collections and macrocephaly: benign enlargement of the subarachnoid spaces versus subdural collections. AJNR Am J Neuroradiol. 14(4):855-60, 1993
            Related Anatomy
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            Related Differential Diagnoses
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            References
            Tables

            Tables

            DIFFERENTIAL DIAGNOSIS

              ESSENTIAL INFORMATION

              • Key Differential Diagnosis Issues

                • Helpful Clues for Common Diagnoses

                  • Helpful Clues for Less Common Diagnoses

                    • Helpful Clues for Rare Diagnoses

                      Selected References

                      1. Libero LE et al: Persistence of megalencephaly in a subgroup of young boys with autism spectrum disorder. Autism Res. 9(11):1169-1182, 2016
                      2. Radoš M et al: Volumetric analysis of cerebrospinal fluid and brain parenchyma in a patient with hydranencephaly and macrocephaly--case report. Croat Med J. 55(4):388-93, 2014
                      3. Colombani M et al: A new case of megalencephaly and perisylvian polymicrogyria with post-axial polydactyly and hydrocephalus: MPPH syndrome. Eur J Med Genet. 49(6):466-71, 2006
                      4. Groeschel S et al: Magnetic resonance imaging and proton magnetic resonance spectroscopy of megalencephaly and dilated Virchow-Robin spaces. Pediatr Neurol. 34(1):35-40, 2006
                      5. D'Ambrosio AL et al: Villous hypertrophy versus choroid plexus papilloma: a case report demonstrating a diagnostic role for the proliferation index. Pediatr Neurosurg. 39(2):91-6, 2003
                      6. Medina LS et al: Children with macrocrania: clinical and imaging predictors of disorders requiring surgery. AJNR Am J Neuroradiol. 22(3):564-70, 2001
                      7. Wilms G et al: CT and MR in infants with pericerebral collections and macrocephaly: benign enlargement of the subarachnoid spaces versus subdural collections. AJNR Am J Neuroradiol. 14(4):855-60, 1993
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