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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Large for gestational age (LGA)
Definitions
- Birth weight (BW) > 4,000 g or 4,500 g (or 10 lb); American College of Obstetrics and Gynecology (ACOG) supports > 4,500 g as morbidity sharply ↑ beyond this weight
- LGA: Estimated fetal weight (EFW) or BW > 90th percentile
- No international standard established
- Country-specific population percentiles would be best
IMAGING
General Features
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
- Duncan JR et al: Prediction of large for gestational age neonates by different growth standards. J Ultrasound Med. 40(5):963-70, 2021
- Bicocca MJ et al: Identification of newborns with birthweight ≥ 4,500g: ultrasound within one- vs. two weeks of delivery. Eur J Obstet Gynecol Reprod Biol. 249:47-53, 2020
- Committee on Practice Bulletins—Obstetrics.: Macrosomia: ACOG practice bulletin, number 216. Obstet Gynecol. 135(1):e18-35, 2020
- Robinson R et al: The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review. Eur J Obstet Gynecol Reprod Biol. 246:79-85, 2020
- Salihu HM et al: Trends in the incidence of fetal macrosomia and its phenotypes in the United States, 1971-2017. Arch Gynecol Obstet. 301(2):415-26, 2020
- Beta J et al: Maternal and neonatal complications of fetal macrosomia: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 54(3):308-18, 2019
- Fang F et al: Risk factors for recurrent macrosomia and child outcomes. World J Pediatr. 15(3):289-96, 2019
- Khan N et al: Prediction of large-for-gestational-age neonate by routine third-trimester ultrasound. Ultrasound Obstet Gynecol. 54(3):326-33, 2019
- Wastlund D et al: The cost-effectiveness of universal late-pregnancy screening for macrosomia in nulliparous women: a decision analysis. BJOG. 126(10):1243-50, 2019
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Large for gestational age (LGA)
Definitions
- Birth weight (BW) > 4,000 g or 4,500 g (or 10 lb); American College of Obstetrics and Gynecology (ACOG) supports > 4,500 g as morbidity sharply ↑ beyond this weight
- LGA: Estimated fetal weight (EFW) or BW > 90th percentile
- No international standard established
- Country-specific population percentiles would be best
IMAGING
General Features
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
- Duncan JR et al: Prediction of large for gestational age neonates by different growth standards. J Ultrasound Med. 40(5):963-70, 2021
- Bicocca MJ et al: Identification of newborns with birthweight ≥ 4,500g: ultrasound within one- vs. two weeks of delivery. Eur J Obstet Gynecol Reprod Biol. 249:47-53, 2020
- Committee on Practice Bulletins—Obstetrics.: Macrosomia: ACOG practice bulletin, number 216. Obstet Gynecol. 135(1):e18-35, 2020
- Robinson R et al: The test accuracy of antenatal ultrasound definitions of fetal macrosomia to predict birth injury: a systematic review. Eur J Obstet Gynecol Reprod Biol. 246:79-85, 2020
- Salihu HM et al: Trends in the incidence of fetal macrosomia and its phenotypes in the United States, 1971-2017. Arch Gynecol Obstet. 301(2):415-26, 2020
- Beta J et al: Maternal and neonatal complications of fetal macrosomia: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 54(3):308-18, 2019
- Fang F et al: Risk factors for recurrent macrosomia and child outcomes. World J Pediatr. 15(3):289-96, 2019
- Khan N et al: Prediction of large-for-gestational-age neonate by routine third-trimester ultrasound. Ultrasound Obstet Gynecol. 54(3):326-33, 2019
- Wastlund D et al: The cost-effectiveness of universal late-pregnancy screening for macrosomia in nulliparous women: a decision analysis. BJOG. 126(10):1243-50, 2019
