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Male, Other Neoplasms
Wei Tse Yang, MBBS; Wendie A. Berg, MD, PhD
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KEY FACTS

  • Terminology

    • Top Differential Diagnoses

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Benign and malignant neoplasms
            • Mesenchymal (vascular, fibrous, dermal)
            • Hematopoietic (primary and secondary)
            • Excluding primary breast carcinoma or gynecomastia

        IMAGING

        • General Features

          • Mammographic Findings

            • Ultrasonographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            CLINICAL ISSUES

                            • Presentation

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Kim SH et al: Ultrasonographic and mammographic findings of male breast disease. J Ultrasound Med. ePub, 2018
                                    2. Lee EJ et al: Multimodality images of myofibroblastoma in the male breast: A case report and a review of the literature. Clin Imaging. 51:300-306, 2018
                                    3. Whorms DS et al: Mesenchymal lesions of the breast: What radiologists need to know. AJR Am J Roentgenol. 211(1):224-233, 2018
                                    4. Yuan WH et al: Clinical and ultrasonographic features of male breast tumors: A retrospective analysis. PLoS One. 13(3):e0194651, 2018
                                    5. El-Attrache B et al: A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review. Int J Surg Case Rep. 37:1-3, 2017
                                    6. Foo ET et al: Value of diagnostic imaging for the symptomatic male breast: Can we avoid unnecessary biopsies? Clin Imaging. 45:86-91, 2017
                                    7. Lattin GE Jr et al: From the radiologic pathology archives: diseases of the male breast: radiologic-pathologic correlation. Radiographics. 33(2):461-89, 2013
                                    8. Ameen R et al: Breast hemangioma: MR appearance with histopathological correlation. J Clin Imaging Sci. 2:53, 2012
                                    9. Surov A et al: Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. Br J Radiol. 85(1014):e195-205, 2012
                                    10. Tilve A et al: Breast hemangiomas: correlation between imaging and pathologic findings. J Clin Ultrasound. 40(8):512-7, 2012
                                    11. Iuanow E et al: Spectrum of disease in the male breast. AJR Am J Roentgenol. 196(3):W247-59, 2011
                                    12. Jesinger RA et al: Vascular abnormalities of the breast: arterial and venous disorders, vascular masses, and mimic lesions with radiologic-pathologic correlation. Radiographics. 31(7):E117-36, 2011
                                    13. Rathod J et al: A rare case of male primary breast lymphoma. J Breast Cancer. 14(4):333-6, 2011
                                    14. Surov A et al: Metastases to the breast from non-mammary malignancies: primary tumors, prevalence, clinical signs, and radiological features. Acad Radiol. 18(5):565-74, 2011
                                    15. Liu SZ et al: Imaging of dermatofibrosarcoma protuberans of breast. Breast J. 16(5):541-3, 2010
                                    16. Yoo EY et al: Myofibroblastoma of the female breast: mammographic, sonographic, and magnetic resonance imaging findings. J Ultrasound Med. 29(12):1833-6, 2010
                                    17. Chen CH et al: Primary basaloid carcinoma of the nipple with associated squamous cell carcinoma in situ. Breast J. 15(4):409-13, 2009
                                    18. Lee SJ et al: Dermatofibrosarcoma protuberans of the breast: imaging features and review of the literature. AJR Am J Roentgenol. 193(1):W64-9, 2009
                                    19. Mesurolle B et al: Sonographic and mammographic appearances of breast hemangioma. AJR Am J Roentgenol. 191(1):W17-22, 2008
                                    20. Chen L et al: Imaging characteristics of malignant lesions of the male breast. Radiographics. 26(4):993-1006, 2006
                                    21. Porter GJ et al: Unusual benign breast lesions. Clin Radiol. 61(7):562-9, 2006
                                    22. Vourtsi A et al: Male breast hemangioma--a rare entity: a case report and review of the literature. Breast J. 12(3):260-2, 2006
                                    23. Kinoshita S et al: Huge cavernous hemangioma arising in a male breast. Breast Cancer. 12(3):231-3, 2005
                                    24. Kwak JY et al: Imaging findings in a case of epidermal inclusion cyst arising within the breast parenchyma. J Clin Ultrasound. 32(3):141-3, 2004
                                    25. Cooper RA et al: Mammographic findings in basal cell carcinoma of the male nipple. AJR Am J Roentgenol. 175(4):1065-6, 2000
                                    26. Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Top Differential Diagnoses

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Definitions

                                            • Benign and malignant neoplasms
                                              • Mesenchymal (vascular, fibrous, dermal)
                                              • Hematopoietic (primary and secondary)
                                              • Excluding primary breast carcinoma or gynecomastia

                                          IMAGING

                                          • General Features

                                            • Mammographic Findings

                                              • Ultrasonographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Nuclear Medicine Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • Staging, Grading, & Classification

                                                            • Gross Pathologic & Surgical Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Kim SH et al: Ultrasonographic and mammographic findings of male breast disease. J Ultrasound Med. ePub, 2018
                                                                      2. Lee EJ et al: Multimodality images of myofibroblastoma in the male breast: A case report and a review of the literature. Clin Imaging. 51:300-306, 2018
                                                                      3. Whorms DS et al: Mesenchymal lesions of the breast: What radiologists need to know. AJR Am J Roentgenol. 211(1):224-233, 2018
                                                                      4. Yuan WH et al: Clinical and ultrasonographic features of male breast tumors: A retrospective analysis. PLoS One. 13(3):e0194651, 2018
                                                                      5. El-Attrache B et al: A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review. Int J Surg Case Rep. 37:1-3, 2017
                                                                      6. Foo ET et al: Value of diagnostic imaging for the symptomatic male breast: Can we avoid unnecessary biopsies? Clin Imaging. 45:86-91, 2017
                                                                      7. Lattin GE Jr et al: From the radiologic pathology archives: diseases of the male breast: radiologic-pathologic correlation. Radiographics. 33(2):461-89, 2013
                                                                      8. Ameen R et al: Breast hemangioma: MR appearance with histopathological correlation. J Clin Imaging Sci. 2:53, 2012
                                                                      9. Surov A et al: Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. Br J Radiol. 85(1014):e195-205, 2012
                                                                      10. Tilve A et al: Breast hemangiomas: correlation between imaging and pathologic findings. J Clin Ultrasound. 40(8):512-7, 2012
                                                                      11. Iuanow E et al: Spectrum of disease in the male breast. AJR Am J Roentgenol. 196(3):W247-59, 2011
                                                                      12. Jesinger RA et al: Vascular abnormalities of the breast: arterial and venous disorders, vascular masses, and mimic lesions with radiologic-pathologic correlation. Radiographics. 31(7):E117-36, 2011
                                                                      13. Rathod J et al: A rare case of male primary breast lymphoma. J Breast Cancer. 14(4):333-6, 2011
                                                                      14. Surov A et al: Metastases to the breast from non-mammary malignancies: primary tumors, prevalence, clinical signs, and radiological features. Acad Radiol. 18(5):565-74, 2011
                                                                      15. Liu SZ et al: Imaging of dermatofibrosarcoma protuberans of breast. Breast J. 16(5):541-3, 2010
                                                                      16. Yoo EY et al: Myofibroblastoma of the female breast: mammographic, sonographic, and magnetic resonance imaging findings. J Ultrasound Med. 29(12):1833-6, 2010
                                                                      17. Chen CH et al: Primary basaloid carcinoma of the nipple with associated squamous cell carcinoma in situ. Breast J. 15(4):409-13, 2009
                                                                      18. Lee SJ et al: Dermatofibrosarcoma protuberans of the breast: imaging features and review of the literature. AJR Am J Roentgenol. 193(1):W64-9, 2009
                                                                      19. Mesurolle B et al: Sonographic and mammographic appearances of breast hemangioma. AJR Am J Roentgenol. 191(1):W17-22, 2008
                                                                      20. Chen L et al: Imaging characteristics of malignant lesions of the male breast. Radiographics. 26(4):993-1006, 2006
                                                                      21. Porter GJ et al: Unusual benign breast lesions. Clin Radiol. 61(7):562-9, 2006
                                                                      22. Vourtsi A et al: Male breast hemangioma--a rare entity: a case report and review of the literature. Breast J. 12(3):260-2, 2006
                                                                      23. Kinoshita S et al: Huge cavernous hemangioma arising in a male breast. Breast Cancer. 12(3):231-3, 2005
                                                                      24. Kwak JY et al: Imaging findings in a case of epidermal inclusion cyst arising within the breast parenchyma. J Clin Ultrasound. 32(3):141-3, 2004
                                                                      25. Cooper RA et al: Mammographic findings in basal cell carcinoma of the male nipple. AJR Am J Roentgenol. 175(4):1065-6, 2000
                                                                      26. Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997