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Malignant Ameloblastoma and Ameloblastic Carcinoma
Byron W. Benson, DDS, MS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Ameloblastic carcinoma exhibits histologic criteria of malignant neoplasm
            • Malignant ameloblastoma is histologically indistinguishable from ameloblastoma but is metastatic clinically
              • Terms are sometimes used interchangeably due to similarities between lesions, but they are indeed different entities

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                Selected References

                                1. Yunaev M et al: A rare case of ameloblastic carcinoma. Ear Nose Throat J. 93(9):E34-6, 2014
                                2. França DC et al: Ameloblastic carcinoma of the maxilla: A case report. Oncol Lett. 4(6):1297-1300, 2012
                                3. Lai H et al: Benign metastasizing ameloblastoma or malignant ameloblastoma? J Craniofac Surg. 22(3):995-7, 2011
                                4. Matsuzaki H et al: Ameloblastic carcinoma: a case report with radiological features of computed tomography and magnetic resonance imaging and positron emission tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 112(1):e40-7, 2011
                                5. Karakida K et al: Ameloblastic carcinoma, secondary type: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 110(6):e33-7, 2010
                                6. Lucca M et al: Ameloblastic carcinoma of the maxilla: a report of 2 cases. J Oral Maxillofac Surg. 68(10):2564-9, 2010
                                7. Van Dam SD et al: Metastasizing (malignant) ameloblastoma: review of a unique histopathologic entity and report of Mayo Clinic experience. J Oral Maxillofac Surg. 68(12):2962-74, 2010
                                8. Ciment LM et al: Malignant ameloblastoma metastatic to the lungs 29 years after primary resection: a case report. Chest. 121(4):1359-61, 2002
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Definitions

                                          • Ameloblastic carcinoma exhibits histologic criteria of malignant neoplasm
                                          • Malignant ameloblastoma is histologically indistinguishable from ameloblastoma but is metastatic clinically
                                            • Terms are sometimes used interchangeably due to similarities between lesions, but they are indeed different entities

                                        IMAGING

                                        • General Features

                                          • Radiographic Findings

                                            • CT Findings

                                              • MR Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • Microscopic Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            • Treatment

                                                              Selected References

                                                              1. Yunaev M et al: A rare case of ameloblastic carcinoma. Ear Nose Throat J. 93(9):E34-6, 2014
                                                              2. França DC et al: Ameloblastic carcinoma of the maxilla: A case report. Oncol Lett. 4(6):1297-1300, 2012
                                                              3. Lai H et al: Benign metastasizing ameloblastoma or malignant ameloblastoma? J Craniofac Surg. 22(3):995-7, 2011
                                                              4. Matsuzaki H et al: Ameloblastic carcinoma: a case report with radiological features of computed tomography and magnetic resonance imaging and positron emission tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 112(1):e40-7, 2011
                                                              5. Karakida K et al: Ameloblastic carcinoma, secondary type: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 110(6):e33-7, 2010
                                                              6. Lucca M et al: Ameloblastic carcinoma of the maxilla: a report of 2 cases. J Oral Maxillofac Surg. 68(10):2564-9, 2010
                                                              7. Van Dam SD et al: Metastasizing (malignant) ameloblastoma: review of a unique histopathologic entity and report of Mayo Clinic experience. J Oral Maxillofac Surg. 68(12):2962-74, 2010
                                                              8. Ciment LM et al: Malignant ameloblastoma metastatic to the lungs 29 years after primary resection: a case report. Chest. 121(4):1359-61, 2002