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Malignant Pleural Mesothelioma
Leif Jensen, MD
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7

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Routes of Spread

        • General Features

          • Gross Pathology & Surgical Features

            • Microscopic Features

              IMAGING FINDINGS

              • Detection

                • Staging

                  • Restaging

                    CLINICAL ISSUES

                    • Presentation

                      • Cancer Natural History & Prognosis

                        • Treatment Options

                          REPORTING CHECKLIST

                          • Potentially Resectable Disease

                            • Technically Nonresectable Disease

                              Selected References

                              1. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                              2. Katzman D et al: Updates in the diagnosis and treatment of malignant pleural mesothelioma. Curr Opin Pulm Med. 24(4):319-26, 2018
                              3. Nickell LT Jr et al: Multimodality imaging for characterization, classification, and staging of malignant pleural mesothelioma. Radiographics. 34(6):1692-706, 2014
                              4. Koegelenberg CF et al: Image-guided pleural biopsy. Curr Opin Pulm Med. 19(4):368-73, 2013
                              5. Gill RR et al: Epithelial malignant pleural mesothelioma after extrapleural pneumonectomy: stratification of survival with CT-derived tumor volume. AJR Am J Roentgenol. 198(2):359-63, 2012
                              6. Nowak AK et al: Imaging in pleural mesothelioma: a review of imaging research presented at the 9th International Meeting of the International Mesothelioma Interest Group. Lung Cancer. 70(1):1-6, 2010
                              7. Scherpereel A et al: Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for the management of malignant pleural mesothelioma. Eur Respir J. 35(3):479-95, 2010
                              8. Tan C et al: Role of integrated 18-fluorodeoxyglucose position emission tomography-computed tomography in patients surveillance after multimodality therapy of malignant pleural mesothelioma. J Thorac Oncol. 5(3):385-8, 2010
                              9. Tanzi S et al: Localized malignant pleural mesothelioma: report of two cases. J Thorac Oncol. 4(8):1038-40, 2009
                              10. Weiner SJ et al: Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors. J Cancer Res Clin Oncol. 135(1):15-27, 2009
                              11. Di Salvo M et al: Prevention of malignant seeding at drain sites after invasive procedures (surgery and/or thoracoscopy) by hypofractionated radiotherapy in patients with pleural mesothelioma. Acta Oncol. 47(6):1094-8, 2008
                              12. Plathow C et al: Computed tomography, positron emission tomography, positron emission tomography/computed tomography, and magnetic resonance imaging for staging of limited pleural mesothelioma: initial results. Invest Radiol. 43(10):737-44, 2008
                              13. O'Rourke N et al: A randomised controlled trial of intervention site radiotherapy in malignant pleural mesothelioma. Radiother Oncol. 84(1):18-22, 2007
                              14. Duysinx B et al: Evaluation of pleural disease with 18-fluorodeoxyglucose positron emission tomography imaging. Chest. 125(2):489-93, 2004
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              OVERVIEW

                              • General Comments

                                • Classification

                                  PATHOLOGY

                                  • Routes of Spread

                                    • General Features

                                      • Gross Pathology & Surgical Features

                                        • Microscopic Features

                                          IMAGING FINDINGS

                                          • Detection

                                            • Staging

                                              • Restaging

                                                CLINICAL ISSUES

                                                • Presentation

                                                  • Cancer Natural History & Prognosis

                                                    • Treatment Options

                                                      REPORTING CHECKLIST

                                                      • Potentially Resectable Disease

                                                        • Technically Nonresectable Disease

                                                          Selected References

                                                          1. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                          2. Katzman D et al: Updates in the diagnosis and treatment of malignant pleural mesothelioma. Curr Opin Pulm Med. 24(4):319-26, 2018
                                                          3. Nickell LT Jr et al: Multimodality imaging for characterization, classification, and staging of malignant pleural mesothelioma. Radiographics. 34(6):1692-706, 2014
                                                          4. Koegelenberg CF et al: Image-guided pleural biopsy. Curr Opin Pulm Med. 19(4):368-73, 2013
                                                          5. Gill RR et al: Epithelial malignant pleural mesothelioma after extrapleural pneumonectomy: stratification of survival with CT-derived tumor volume. AJR Am J Roentgenol. 198(2):359-63, 2012
                                                          6. Nowak AK et al: Imaging in pleural mesothelioma: a review of imaging research presented at the 9th International Meeting of the International Mesothelioma Interest Group. Lung Cancer. 70(1):1-6, 2010
                                                          7. Scherpereel A et al: Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for the management of malignant pleural mesothelioma. Eur Respir J. 35(3):479-95, 2010
                                                          8. Tan C et al: Role of integrated 18-fluorodeoxyglucose position emission tomography-computed tomography in patients surveillance after multimodality therapy of malignant pleural mesothelioma. J Thorac Oncol. 5(3):385-8, 2010
                                                          9. Tanzi S et al: Localized malignant pleural mesothelioma: report of two cases. J Thorac Oncol. 4(8):1038-40, 2009
                                                          10. Weiner SJ et al: Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors. J Cancer Res Clin Oncol. 135(1):15-27, 2009
                                                          11. Di Salvo M et al: Prevention of malignant seeding at drain sites after invasive procedures (surgery and/or thoracoscopy) by hypofractionated radiotherapy in patients with pleural mesothelioma. Acta Oncol. 47(6):1094-8, 2008
                                                          12. Plathow C et al: Computed tomography, positron emission tomography, positron emission tomography/computed tomography, and magnetic resonance imaging for staging of limited pleural mesothelioma: initial results. Invest Radiol. 43(10):737-44, 2008
                                                          13. O'Rourke N et al: A randomised controlled trial of intervention site radiotherapy in malignant pleural mesothelioma. Radiother Oncol. 84(1):18-22, 2007
                                                          14. Duysinx B et al: Evaluation of pleural disease with 18-fluorodeoxyglucose positron emission tomography imaging. Chest. 125(2):489-93, 2004