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Mandible-Maxilla Central Giant Cell Granuloma
Sara Strauss, MDKristine M. Mosier, DMD, PhD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Central giant cell granuloma (CGCG)
              • Synonyms

                • Giant cell reparative granuloma
              • Definitions

                • Giant cell reparative lesion of mandible or maxilla

              IMAGING

              • General Features

                • Imaging Recommendations

                  • CT Findings

                    • MR Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Alsufyani NA et al: A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws. Acta Odontol Scand. 79(2):124-31, 2021
                                    2. Etoz M et al: Central giant cell granulomas of the jaws: retrospective radiographic analysis of 13 patients. Oral Radiol. 36(1):60-8, 2020
                                    3. Slootweg, P. Giant Cell Lesions. In: Pathology of the Maxillofacial Bones. 157-70. Springer, 2015
                                    4. Triantafillidou K et al: Central giant cell granuloma of the jaws: a clinical study of 17 cases and a review of the literature. Ann Otol Rhinol Laryngol. 120(3):167-74, 2011
                                    5. Nackos JS et al: CT and MR imaging of giant cell granuloma of the craniofacial bones. AJNR Am J Neuroradiol. 27(8):1651-3, 2006
                                    6. Murphey MD et al: From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. Radiographics. 21(5):1283-309, 2001
                                    7. Dos Santos LA et al: Effectiveness of computed tomography to evaluate central giant cell lesion. Dentomaxillofac Radiol. 36(8):522-5, 2007
                                    8. Morris JM et al: Giant cell reparative granuloma of the nasal cavity. AJNR Am J Neuroradiol. 25(7):1263-5, 2004
                                    9. Aralasmak A et al: Giant cell reparative granuloma of the sphenoid bone. AJNR Am J Neuroradiol. 27(8):1675-7, 2006
                                    10. Regezi JA: Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Mod Pathol. 15(3):331-41, 2002
                                    11. Etemadi J et al: Brown tumor of hyperparathyroidism masquerading as central giant cell granuloma in a renal transplant recipient: a case report. Transplant Proc. 41(7):2920-2, 2009
                                    12. Whitaker SB et al: Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study. Oral Surg Oral Med Oral Pathol. 75(2):199-208, 1993
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Central giant cell granuloma (CGCG)
                                                • Synonyms

                                                  • Giant cell reparative granuloma
                                                • Definitions

                                                  • Giant cell reparative lesion of mandible or maxilla

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Alsufyani NA et al: A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws. Acta Odontol Scand. 79(2):124-31, 2021
                                                                      2. Etoz M et al: Central giant cell granulomas of the jaws: retrospective radiographic analysis of 13 patients. Oral Radiol. 36(1):60-8, 2020
                                                                      3. Slootweg, P. Giant Cell Lesions. In: Pathology of the Maxillofacial Bones. 157-70. Springer, 2015
                                                                      4. Triantafillidou K et al: Central giant cell granuloma of the jaws: a clinical study of 17 cases and a review of the literature. Ann Otol Rhinol Laryngol. 120(3):167-74, 2011
                                                                      5. Nackos JS et al: CT and MR imaging of giant cell granuloma of the craniofacial bones. AJNR Am J Neuroradiol. 27(8):1651-3, 2006
                                                                      6. Murphey MD et al: From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. Radiographics. 21(5):1283-309, 2001
                                                                      7. Dos Santos LA et al: Effectiveness of computed tomography to evaluate central giant cell lesion. Dentomaxillofac Radiol. 36(8):522-5, 2007
                                                                      8. Morris JM et al: Giant cell reparative granuloma of the nasal cavity. AJNR Am J Neuroradiol. 25(7):1263-5, 2004
                                                                      9. Aralasmak A et al: Giant cell reparative granuloma of the sphenoid bone. AJNR Am J Neuroradiol. 27(8):1675-7, 2006
                                                                      10. Regezi JA: Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Mod Pathol. 15(3):331-41, 2002
                                                                      11. Etemadi J et al: Brown tumor of hyperparathyroidism masquerading as central giant cell granuloma in a renal transplant recipient: a case report. Transplant Proc. 41(7):2920-2, 2009
                                                                      12. Whitaker SB et al: Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study. Oral Surg Oral Med Oral Pathol. 75(2):199-208, 1993