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Mandible-Maxilla Florid Osseous Dysplasia
C. Grace Petrikowski, DDS, MSc, FRCD(C)
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Florid osseous dysplasia (FOD)
            • Synonyms

              • Florid cementoosseous dysplasia, florid-ossifying dysplasia, gigantiform cementoma, familial multiple cementomas, multiple periapical osteofibromatosis, familial gigantiform cementoma, sclerotic cemental masses
            • Definitions

              • Extensive form of periapical osseous dysplasia (POD) affecting 3 or more quadrants or widespread involvement in 1 jaw
                • "Florid" indicates multiquadrant involvement
              • Nonneoplastic process confined to tooth-bearing areas of jaws
              • Normal trabecular bone replaced with dense acellular cemental and osseous tissue in fibrous tissue stroma

            IMAGING

            • General Features

              • Imaging Recommendations

                • Radiographic Findings

                  • CT Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Akbulut S et al: Maxillectomy for cementifying osseous dysplasia of the maxilla: a case report. Acta Medica (Hradec Kralove). 58(1):32-4, 2015
                                        2. Delai D et al: Florid cemento-osseous dysplasia: a case of misdiagnosis. J Endod. 41(11):1923-6, 2015
                                        3. Thorawat A et al: Familial florid cemento-osseous dysplasia - case report and review of literature. Clin Case Rep. 3(12):1034-7, 2015
                                        4. de Noronha Santos Netto J et al: Benign fibro-osseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol. 115(5):e56-65, 2013
                                        5. Kutluay Köklü H et al: Florid cemento-osseous dysplasia: Report of a case documented with clinical, radiographic, biochemical and histological findings. J Clin Exp Dent. 5(1):e58-61, 2013
                                        6. Kumar VV et al: Clinicopathologic conference: multiquadrant expansile fibro-osseous lesion in a juvenile. Oral Surg Oral Med Oral Pathol Oral Radiol. 113(3):286-92, 2012
                                        7. Singer SR et al: Florid cemento-osseous dysplasia and chronic diffuse osteomyelitis report of a simultaneous presentation and review of the literature. J Am Dent Assoc. 136(7):927-31, 2005
                                        8. MacDonald-Jankowski DS: Florid cemento-osseous dysplasia: a systematic review. Dentomaxillofac Radiol. 32(3):141-9, 2003
                                        9. Beylouni I et al: Florid cemento-osseous dysplasia: Report of a case documented with computed tomography and 3D imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 85(6):707-11, 1998
                                        10. Ariji Y et al: Florid cemento-osseous dysplasia. radiographic study with special emphasis on computed tomography. Oral Surg Oral Med Oral Pathol. 78(3):391-6, 1994
                                        11. Summerlin DJ et al: Focal cemento-osseous dysplasia: a clinicopathologic study of 221 cases. Oral Surg Oral Med Oral Pathol. 78(5):611-20, 1994
                                        12. Loh FC et al: Florid osseous dysplasia in Orientals. Oral Surg Oral Med Oral Pathol. 68(6):748-53, 1989
                                        13. Horner K et al: Atypical simple bone cysts of the jaws. II: A possible association with benign fibro-osseous (cemental) lesions of the jaws. Clin Radiol. 39(1):59-63, 1988
                                        14. Melrose RJ et al: Florid osseous dysplasia. A clinical-pathologic study of thirty-four cases. Oral Surg Oral Med Oral Pathol. 41(1):62-82, 1976
                                        15. Waldron CA et al: Sclerotic cemental masses of the jaws (so-called chronic sclerosing osteomyelitis, sclerosing osteitis, multiple enostosis, and gigantiform cementoma. Oral Surg Oral Med Oral Pathol. 39(4):590-604, 1975
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Florid osseous dysplasia (FOD)
                                                  • Synonyms

                                                    • Florid cementoosseous dysplasia, florid-ossifying dysplasia, gigantiform cementoma, familial multiple cementomas, multiple periapical osteofibromatosis, familial gigantiform cementoma, sclerotic cemental masses
                                                  • Definitions

                                                    • Extensive form of periapical osseous dysplasia (POD) affecting 3 or more quadrants or widespread involvement in 1 jaw
                                                      • "Florid" indicates multiquadrant involvement
                                                    • Nonneoplastic process confined to tooth-bearing areas of jaws
                                                    • Normal trabecular bone replaced with dense acellular cemental and osseous tissue in fibrous tissue stroma

                                                  IMAGING

                                                  • General Features

                                                    • Imaging Recommendations

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Staging, Grading, & Classification

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Akbulut S et al: Maxillectomy for cementifying osseous dysplasia of the maxilla: a case report. Acta Medica (Hradec Kralove). 58(1):32-4, 2015
                                                                              2. Delai D et al: Florid cemento-osseous dysplasia: a case of misdiagnosis. J Endod. 41(11):1923-6, 2015
                                                                              3. Thorawat A et al: Familial florid cemento-osseous dysplasia - case report and review of literature. Clin Case Rep. 3(12):1034-7, 2015
                                                                              4. de Noronha Santos Netto J et al: Benign fibro-osseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol. 115(5):e56-65, 2013
                                                                              5. Kutluay Köklü H et al: Florid cemento-osseous dysplasia: Report of a case documented with clinical, radiographic, biochemical and histological findings. J Clin Exp Dent. 5(1):e58-61, 2013
                                                                              6. Kumar VV et al: Clinicopathologic conference: multiquadrant expansile fibro-osseous lesion in a juvenile. Oral Surg Oral Med Oral Pathol Oral Radiol. 113(3):286-92, 2012
                                                                              7. Singer SR et al: Florid cemento-osseous dysplasia and chronic diffuse osteomyelitis report of a simultaneous presentation and review of the literature. J Am Dent Assoc. 136(7):927-31, 2005
                                                                              8. MacDonald-Jankowski DS: Florid cemento-osseous dysplasia: a systematic review. Dentomaxillofac Radiol. 32(3):141-9, 2003
                                                                              9. Beylouni I et al: Florid cemento-osseous dysplasia: Report of a case documented with computed tomography and 3D imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 85(6):707-11, 1998
                                                                              10. Ariji Y et al: Florid cemento-osseous dysplasia. radiographic study with special emphasis on computed tomography. Oral Surg Oral Med Oral Pathol. 78(3):391-6, 1994
                                                                              11. Summerlin DJ et al: Focal cemento-osseous dysplasia: a clinicopathologic study of 221 cases. Oral Surg Oral Med Oral Pathol. 78(5):611-20, 1994
                                                                              12. Loh FC et al: Florid osseous dysplasia in Orientals. Oral Surg Oral Med Oral Pathol. 68(6):748-53, 1989
                                                                              13. Horner K et al: Atypical simple bone cysts of the jaws. II: A possible association with benign fibro-osseous (cemental) lesions of the jaws. Clin Radiol. 39(1):59-63, 1988
                                                                              14. Melrose RJ et al: Florid osseous dysplasia. A clinical-pathologic study of thirty-four cases. Oral Surg Oral Med Oral Pathol. 41(1):62-82, 1976
                                                                              15. Waldron CA et al: Sclerotic cemental masses of the jaws (so-called chronic sclerosing osteomyelitis, sclerosing osteitis, multiple enostosis, and gigantiform cementoma. Oral Surg Oral Med Oral Pathol. 39(4):590-604, 1975