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Mandible-Maxilla Osteoblastoma
Lisa J. Koenig, BChD, DDS, MS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Giant osteoid osteoma, giant osteogenic fibroma
              • Definitions

                • Benign tumor of bone arising from osteoblasts and accounting for ~ 1% of all bone tumors

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Emanuelsson J et al: Osteoblastoma of the temporal articular tubercle misdiagnosed as a temporomandibular joint disorder. Int J Oral Maxillofac Surg. ePub, 2016
                                        2. Rana V et al: Epithelioid osteoblastoma of maxilla: A rare and aggressive variant of a benign neoplasm at an uncommon site. J Oral Maxillofac Pathol. 20(2):332, 2016
                                        3. Mardaleishvili K et al: Benign osteoblastoma of the mandible in a 12-year-old female: A case report. Oncol Lett. 8(6):2691-2694, 2014
                                        4. Pontual ML et al: Aggressive multilocular osteoblastoma in the mandible: a rare and difficult case to diagnose. Braz Dent J. 25(5):451-6, 2014
                                        5. Mahajan A et al: Osteoblastoma in the retromolar region - Report of an unusual case and Review of literature. J Maxillofac Oral Surg. 12(3):338-40, 2013
                                        6. Strobel K et al: Osteoblastoma of the mandible mimicking osteosarcoma in FDG PET/CT imaging. Clin Nucl Med. 38(2):143-4, 2013
                                        7. Bokhari K et al: Benign osteoblastoma involving maxilla: a case report and review of the literature. Case Rep Dent. 2012:351241, 2012
                                        8. Kaur H et al: Aggressive osteoblastoma of the mandible: A diagnostic dilemma. Dent Res J (Isfahan). 9(3):334-7, 2012
                                        9. Harrington C et al: Aggressive osteoblastoma of the maxilla: a case report and review of the literature. Head Neck Pathol. 5(2):165-70, 2011
                                        10. Manjunatha BS et al: Osteoblastoma of the jaws: report of a case and review of literature. Clin Pract. 1(4):e118, 2011
                                        11. Woźniak AW et al: Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol. 267(6):845-9, 2010
                                        12. Lypka MA et al: Aggressive osteoblastoma of the mandible. Int J Oral Maxillofac Surg. 37(7):675-8, 2008
                                        13. Jones AC et al: Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 102(5):639-50, 2006
                                        14. Rawal YB et al: Gnathic osteoblastoma: clinicopathologic review of seven cases with long-term follow-up. Oral Oncol. 42(2):123-30, 2006
                                        15. Alvares Capelozza AL et al: Osteoblastoma of the mandible: systematic review of the literature and report of a case. Dentomaxillofac Radiol. 34(1):1-8, 2005
                                        16. Capodiferro S et al: Osteoblastoma of the mandible: clinicopathologic study of four cases and literature review. Head Neck. 27(7):616-21, 2005
                                        17. Bilkay U et al: A rare location of benign osteoblastoma: review of the literature and report of a case. J Craniofac Surg. 15(2):222-5, 2004
                                        18. Bsoul SA et al: Osteoblastoma. Quintessence Int. 35(2):164-5, 2004
                                        19. Oztürk M et al: Osteoblastoma of the mandible with root resorption: a case report. Quintessence Int. 34(2):135-8, 2003
                                        20. Matsuzaka K et al: Lesions related to the formation of bone, cartilage or cementum arising in the oral area: a statistical study and review of the literature. Bull Tokyo Dent Coll. 43(3):173-80, 2002
                                        21. Gordon SC et al: A review of osteoblastoma and case report of metachronous osteoblastoma and unicystic ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91(5):570-5, 2001
                                        22. Svensson B et al: Benign osteoblastoma associated with an aneurysmal bone cyst of the mandibular ramus and condyle. Oral Surg Oral Med Oral Pathol. 76(4):433-6, 1993
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Giant osteoid osteoma, giant osteogenic fibroma
                                                    • Definitions

                                                      • Benign tumor of bone arising from osteoblasts and accounting for ~ 1% of all bone tumors

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Staging, Grading, & Classification

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Emanuelsson J et al: Osteoblastoma of the temporal articular tubercle misdiagnosed as a temporomandibular joint disorder. Int J Oral Maxillofac Surg. ePub, 2016
                                                                              2. Rana V et al: Epithelioid osteoblastoma of maxilla: A rare and aggressive variant of a benign neoplasm at an uncommon site. J Oral Maxillofac Pathol. 20(2):332, 2016
                                                                              3. Mardaleishvili K et al: Benign osteoblastoma of the mandible in a 12-year-old female: A case report. Oncol Lett. 8(6):2691-2694, 2014
                                                                              4. Pontual ML et al: Aggressive multilocular osteoblastoma in the mandible: a rare and difficult case to diagnose. Braz Dent J. 25(5):451-6, 2014
                                                                              5. Mahajan A et al: Osteoblastoma in the retromolar region - Report of an unusual case and Review of literature. J Maxillofac Oral Surg. 12(3):338-40, 2013
                                                                              6. Strobel K et al: Osteoblastoma of the mandible mimicking osteosarcoma in FDG PET/CT imaging. Clin Nucl Med. 38(2):143-4, 2013
                                                                              7. Bokhari K et al: Benign osteoblastoma involving maxilla: a case report and review of the literature. Case Rep Dent. 2012:351241, 2012
                                                                              8. Kaur H et al: Aggressive osteoblastoma of the mandible: A diagnostic dilemma. Dent Res J (Isfahan). 9(3):334-7, 2012
                                                                              9. Harrington C et al: Aggressive osteoblastoma of the maxilla: a case report and review of the literature. Head Neck Pathol. 5(2):165-70, 2011
                                                                              10. Manjunatha BS et al: Osteoblastoma of the jaws: report of a case and review of literature. Clin Pract. 1(4):e118, 2011
                                                                              11. Woźniak AW et al: Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol. 267(6):845-9, 2010
                                                                              12. Lypka MA et al: Aggressive osteoblastoma of the mandible. Int J Oral Maxillofac Surg. 37(7):675-8, 2008
                                                                              13. Jones AC et al: Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 102(5):639-50, 2006
                                                                              14. Rawal YB et al: Gnathic osteoblastoma: clinicopathologic review of seven cases with long-term follow-up. Oral Oncol. 42(2):123-30, 2006
                                                                              15. Alvares Capelozza AL et al: Osteoblastoma of the mandible: systematic review of the literature and report of a case. Dentomaxillofac Radiol. 34(1):1-8, 2005
                                                                              16. Capodiferro S et al: Osteoblastoma of the mandible: clinicopathologic study of four cases and literature review. Head Neck. 27(7):616-21, 2005
                                                                              17. Bilkay U et al: A rare location of benign osteoblastoma: review of the literature and report of a case. J Craniofac Surg. 15(2):222-5, 2004
                                                                              18. Bsoul SA et al: Osteoblastoma. Quintessence Int. 35(2):164-5, 2004
                                                                              19. Oztürk M et al: Osteoblastoma of the mandible with root resorption: a case report. Quintessence Int. 34(2):135-8, 2003
                                                                              20. Matsuzaka K et al: Lesions related to the formation of bone, cartilage or cementum arising in the oral area: a statistical study and review of the literature. Bull Tokyo Dent Coll. 43(3):173-80, 2002
                                                                              21. Gordon SC et al: A review of osteoblastoma and case report of metachronous osteoblastoma and unicystic ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91(5):570-5, 2001
                                                                              22. Svensson B et al: Benign osteoblastoma associated with an aneurysmal bone cyst of the mandibular ramus and condyle. Oral Surg Oral Med Oral Pathol. 76(4):433-6, 1993