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Head and Neck
Diagnosis
Masticator Space
Malignant Tumors
Masticator Space Chondrosarcoma
Masticator Space Chondrosarcoma
Bronwyn E. Hamilton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Chondrosarcoma (CSa)

          • Definitions

            • CSa-masticator space (MS): Malignant tumor of cartilage that originates in MS

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Stanbouly D et al: Mesenchymal chondrosarcoma in the maxilla: a case report and literature review. J Oral Maxillofac Surg. 79(8):1706-11, 2021
                                          2. Almansoori AA et al: Chondrosarcoma of the jaw: a retrospective series. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(2):106-11, 2019
                                          3. de Souza LL et al: Chondrosarcoma of the jaw bones: a review of 224 cases reported to date and an analysis of prognostic factors. Int J Oral Maxillofac Surg. 48(4):452-60, 2019
                                          4. Romañach MJ et al: Extraskeletal myxoid chondrosarcoma of the masticator space in a pediatric patient. J Clin Exp Dent. 9(6):e825-31, 2017
                                          5. Nomura T et al: A case of chondrosarcoma arising in the temporomandibular joint. Case Rep Otolaryngol. 2015:832532, 2015
                                          6. De Coninck T et al: Dynamic contrast-enhanced MR imaging for differentiation between enchondroma and chondrosarcoma. Eur Radiol. 23(11):3140-52, 2013
                                          7. Yoshimura Y et al: Preoperative radiographic and histopathologic evaluation of central chondrosarcoma. Arch Orthop Trauma Surg. 133(9):1225-31, 2013
                                          8. Meltzer DE et al: Masticator space: imaging anatomy for diagnosis. Otolaryngol Clin North Am. 45(6):1233-51, 2012
                                          9. Pontes HA et al: Clinicopathological analysis of head and neck chondrosarcoma: three case reports and literature review. Int J Oral Maxillofac Surg. 41(2):203-10, 2012
                                          10. Oliveira RC et al: Chondrosarcoma of the temporomandibular joint: a case report in a child. J Orofac Pain. 23(3):275-81, 2009
                                          11. Acar GO et al: Chondrosarcoma of the mandible extending to the infratemporal fossa: report of two cases. Oral Maxillofac Surg. 12(3):173-6, 2008
                                          12. Sammartino G et al: Chondrosarcoma of the jaw: a closer look at its management. J Oral Maxillofac Surg. 66(11):2349-55, 2008
                                          13. Angiero F et al: Mesenchymal chondrosarcoma of the left coronoid process: report of a unique case with clinical, histopathologic, and immunohistochemical findings, and a review of the literature. Quintessence Int. 38(4):349-55, 2007
                                          14. Saini R et al: Chondrosarcoma of the mandible: a case report. J Can Dent Assoc. 73(2):175-8, 2007
                                          15. Van Damme PA et al: Juxtacortical chondrosarcoma of the mandible: report of a unique case and review of the literature. Int J Oral Maxillofac Surg. 34(1):94-8, 2005
                                          16. Atanasov DT et al: Sarcomas of the mandible. Literature review and case reports. Folia Med (Plovdiv). 46(2):31-5, 2004
                                          17. Bernasconi G et al: Parosteal chondrosarcoma, a very rare condition of the mandibular condyle. Clin Imaging. 28(1):64-8, 2004
                                          18. Antonio SM et al: Mesenchymal chondrosarcoma presenting as an external auditory canal mass. Otol Neurotol. 24(2):344-5, 2003
                                          19. Murphey MD et al. Imaging of primary chondrosarcoma: radiologic-pathologic correlation. RadioGraphics 23:1245-1278. 2003
                                          20. Gorsky M et al: Craniofacial osseous and chondromatous sarcomas in British Columbia--a review of 34 cases. Oral Oncol. 36(1):27-31, 2000
                                          21. Koch BB et al: National cancer database report on chondrosarcoma of the head and neck. Head Neck. 22(4):408-25, 2000
                                          22. Lomoschitz F et al: Quiz case: CPPD crystal deposition disease. Eur J Radiol. 35(1):78-80, 2000
                                          23. Batra PS et al: Chondrosarcoma of the temporomandibular joint. Otolaryngol Head Neck Surg. 120(6):951-4, 1999
                                          24. Sesenna E et al: Chondrosarcoma of the temporomandibular joint: a case report and review of the literature. J Oral Maxillofac Surg. 55(11):1348-52, 1997
                                          25. Anract P et al: [Synovial chondromatosis and chondrosarcoma. A study of the relationship between these two diseases.] Rev Chir Orthop Reparatrice Appar Mot. 82(3):216-24, 1996
                                          26. Saito K et al: Chondrosarcoma of the jaw and facial bones. Cancer. 76(9):1550-8, 1995
                                          27. Ormiston IW et al: Chondrosarcoma of the mandible presenting as periodontal lesions: report of 2 cases. J Craniomaxillofac Surg. 22(4):231-5, 1994
                                          28. Takahashi K et al: Mesenchymal chondrosarcoma of the jaw--report of a case and review of 41 cases in the literature. Head Neck. 15(5):459-64, 1993
                                          29. Wanebo HJ et al: Head and neck sarcoma: report of the Head and Neck Sarcoma Registry. Society of Head and Neck Surgeons Committee on Research. Head Neck. 14(1):1-7, 1992
                                          30. Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
                                          31. Garrington GE et al: Chondrosarcoma. II. Chondrosarcoma of the jaws: analysis of 37 cases. J Oral Pathol. 17(1):12-20, 1988
                                          32. Hardin CW et al: Infection and tumor of the masticator space: CT evaluation. Radiology. 157(2):413-7, 1985
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Chondrosarcoma (CSa)

                                                  • Definitions

                                                    • CSa-masticator space (MS): Malignant tumor of cartilage that originates in MS

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Stanbouly D et al: Mesenchymal chondrosarcoma in the maxilla: a case report and literature review. J Oral Maxillofac Surg. 79(8):1706-11, 2021
                                                                                  2. Almansoori AA et al: Chondrosarcoma of the jaw: a retrospective series. Oral Surg Oral Med Oral Pathol Oral Radiol. 128(2):106-11, 2019
                                                                                  3. de Souza LL et al: Chondrosarcoma of the jaw bones: a review of 224 cases reported to date and an analysis of prognostic factors. Int J Oral Maxillofac Surg. 48(4):452-60, 2019
                                                                                  4. Romañach MJ et al: Extraskeletal myxoid chondrosarcoma of the masticator space in a pediatric patient. J Clin Exp Dent. 9(6):e825-31, 2017
                                                                                  5. Nomura T et al: A case of chondrosarcoma arising in the temporomandibular joint. Case Rep Otolaryngol. 2015:832532, 2015
                                                                                  6. De Coninck T et al: Dynamic contrast-enhanced MR imaging for differentiation between enchondroma and chondrosarcoma. Eur Radiol. 23(11):3140-52, 2013
                                                                                  7. Yoshimura Y et al: Preoperative radiographic and histopathologic evaluation of central chondrosarcoma. Arch Orthop Trauma Surg. 133(9):1225-31, 2013
                                                                                  8. Meltzer DE et al: Masticator space: imaging anatomy for diagnosis. Otolaryngol Clin North Am. 45(6):1233-51, 2012
                                                                                  9. Pontes HA et al: Clinicopathological analysis of head and neck chondrosarcoma: three case reports and literature review. Int J Oral Maxillofac Surg. 41(2):203-10, 2012
                                                                                  10. Oliveira RC et al: Chondrosarcoma of the temporomandibular joint: a case report in a child. J Orofac Pain. 23(3):275-81, 2009
                                                                                  11. Acar GO et al: Chondrosarcoma of the mandible extending to the infratemporal fossa: report of two cases. Oral Maxillofac Surg. 12(3):173-6, 2008
                                                                                  12. Sammartino G et al: Chondrosarcoma of the jaw: a closer look at its management. J Oral Maxillofac Surg. 66(11):2349-55, 2008
                                                                                  13. Angiero F et al: Mesenchymal chondrosarcoma of the left coronoid process: report of a unique case with clinical, histopathologic, and immunohistochemical findings, and a review of the literature. Quintessence Int. 38(4):349-55, 2007
                                                                                  14. Saini R et al: Chondrosarcoma of the mandible: a case report. J Can Dent Assoc. 73(2):175-8, 2007
                                                                                  15. Van Damme PA et al: Juxtacortical chondrosarcoma of the mandible: report of a unique case and review of the literature. Int J Oral Maxillofac Surg. 34(1):94-8, 2005
                                                                                  16. Atanasov DT et al: Sarcomas of the mandible. Literature review and case reports. Folia Med (Plovdiv). 46(2):31-5, 2004
                                                                                  17. Bernasconi G et al: Parosteal chondrosarcoma, a very rare condition of the mandibular condyle. Clin Imaging. 28(1):64-8, 2004
                                                                                  18. Antonio SM et al: Mesenchymal chondrosarcoma presenting as an external auditory canal mass. Otol Neurotol. 24(2):344-5, 2003
                                                                                  19. Murphey MD et al. Imaging of primary chondrosarcoma: radiologic-pathologic correlation. RadioGraphics 23:1245-1278. 2003
                                                                                  20. Gorsky M et al: Craniofacial osseous and chondromatous sarcomas in British Columbia--a review of 34 cases. Oral Oncol. 36(1):27-31, 2000
                                                                                  21. Koch BB et al: National cancer database report on chondrosarcoma of the head and neck. Head Neck. 22(4):408-25, 2000
                                                                                  22. Lomoschitz F et al: Quiz case: CPPD crystal deposition disease. Eur J Radiol. 35(1):78-80, 2000
                                                                                  23. Batra PS et al: Chondrosarcoma of the temporomandibular joint. Otolaryngol Head Neck Surg. 120(6):951-4, 1999
                                                                                  24. Sesenna E et al: Chondrosarcoma of the temporomandibular joint: a case report and review of the literature. J Oral Maxillofac Surg. 55(11):1348-52, 1997
                                                                                  25. Anract P et al: [Synovial chondromatosis and chondrosarcoma. A study of the relationship between these two diseases.] Rev Chir Orthop Reparatrice Appar Mot. 82(3):216-24, 1996
                                                                                  26. Saito K et al: Chondrosarcoma of the jaw and facial bones. Cancer. 76(9):1550-8, 1995
                                                                                  27. Ormiston IW et al: Chondrosarcoma of the mandible presenting as periodontal lesions: report of 2 cases. J Craniomaxillofac Surg. 22(4):231-5, 1994
                                                                                  28. Takahashi K et al: Mesenchymal chondrosarcoma of the jaw--report of a case and review of 41 cases in the literature. Head Neck. 15(5):459-64, 1993
                                                                                  29. Wanebo HJ et al: Head and neck sarcoma: report of the Head and Neck Sarcoma Registry. Society of Head and Neck Surgeons Committee on Research. Head Neck. 14(1):1-7, 1992
                                                                                  30. Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
                                                                                  31. Garrington GE et al: Chondrosarcoma. II. Chondrosarcoma of the jaws: analysis of 37 cases. J Oral Pathol. 17(1):12-20, 1988
                                                                                  32. Hardin CW et al: Infection and tumor of the masticator space: CT evaluation. Radiology. 157(2):413-7, 1985