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Masticator Space CNV3 Schwannoma
Bronwyn E. Hamilton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Masticator space (MS) CNV3 (mandibular branch, trigeminal nerve) schwannoma
            • Synonyms

              • Neuroma, neurilemmoma, neurinoma
            • Definitions

              • Encapsulated tumor of Schwann cell, which displaces rather than infiltrates fascicles of CNV3 in MS

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Angiographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          • Surgical classification by location

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
                                                2. Lyra TG et al: Gasserian ganglion neurosarcoidosis mimicking trigeminal schwannoma. Arq Neuropsiquiatr. 73(2):173-4, 2015
                                                3. Chen LF et al: Operative management of trigeminal neuromas: an analysis of a surgical experience with 55 cases. Acta Neurochir (Wien). 156(6):1105-14, 2014
                                                4. Buric N et al: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol. 38(3):178-81, 2009
                                                5. Baranović M et al: Schwannoma with secondary erosion of mandible: case report with a review of the literature. Dentomaxillofac Radiol. 35(6):456-60, 2006
                                                6. Kowatsch E et al: Extraosseous schwannoma of the mental nerve clinically simulating intraosseous. J Oral Pathol Med. 35(8):517-9, 2006
                                                7. Yamazaki H et al: Schwannoma of the mental nerve: usefulness of preoperative imaging: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(1):122-6, 2004
                                                8. Al-Mefty O et al: Trigeminal schwannomas: removal of dumbbell-shaped tumors through the expanded Meckel cave and outcomes of cranial nerve function. J Neurosurg. 96(3):453-63, 2002
                                                9. Go JL et al: The trigeminal nerve. Semin Ultrasound CT MR. 22(6):502-20, 2001
                                                10. Martinoli C et al: Ultrasonography of peripheral nerves. Semin Ultrasound CT MR. 21(3):205-13, 2000
                                                11. Mostafapour SP et al: Tumors and tumorous masses presenting as temporomandibular joint syndrome. Otolaryngol Head Neck Surg. 123(4):459-64, 2000
                                                12. Schisano G: Stereotactic radiosurgery for trigeminal schwannomas. Neurosurgery. 46(4):1025-6, 2000
                                                13. Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
                                                14. Majoie CB et al: Primary nerve-sheath tumours of the trigeminal nerve: clinical and MRI findings. Neuroradiology. 41(2):100-8, 1999
                                                15. Sim RJ et al: Trigeminal neurinoma presenting with trismus. J Laryngol Otol. 113(12):1112-3, 1999
                                                16. Torossian JM et al: Extracranial cephalic schwannomas: a series of 15 patients. J Craniofac Surg. 10(5):389-94, 1999
                                                17. Krishnamurthy S et al: Schwannomas limited to the infratemporal fossa: report of two cases. J Neurooncol. 36(3):269-77, 1998
                                                18. Konovalov AN et al: Trigeminal neurinomas. A series of 111 surgical cases from a single institution. Acta Neurochir (Wien). 138(9):1027-35, 1996
                                                19. Nemzek WR: The trigeminal nerve. Top Magn Reson Imaging. 8(3):132-54, 1996
                                                20. Aspestrand F et al: CT and MR imaging of primary tumors of the masticator space. Acta Radiol. 33(6):518-22, 1992
                                                21. Marsot-Dupuch K et al: Mandibular nerve: MR versus CT about 10 proved unusual tumors. Neuroradiology. 32(6):492-6, 1990
                                                22. Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
                                                23. Pollack IF et al: Neurilemomas of the trigeminal nerve. J Neurosurg. 70(5):737-45, 1989
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Masticator space (MS) CNV3 (mandibular branch, trigeminal nerve) schwannoma
                                                          • Synonyms

                                                            • Neuroma, neurilemmoma, neurinoma
                                                          • Definitions

                                                            • Encapsulated tumor of Schwann cell, which displaces rather than infiltrates fascicles of CNV3 in MS

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Ultrasonographic Findings

                                                                    • Angiographic Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        • Surgical classification by location

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
                                                                                              2. Lyra TG et al: Gasserian ganglion neurosarcoidosis mimicking trigeminal schwannoma. Arq Neuropsiquiatr. 73(2):173-4, 2015
                                                                                              3. Chen LF et al: Operative management of trigeminal neuromas: an analysis of a surgical experience with 55 cases. Acta Neurochir (Wien). 156(6):1105-14, 2014
                                                                                              4. Buric N et al: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol. 38(3):178-81, 2009
                                                                                              5. Baranović M et al: Schwannoma with secondary erosion of mandible: case report with a review of the literature. Dentomaxillofac Radiol. 35(6):456-60, 2006
                                                                                              6. Kowatsch E et al: Extraosseous schwannoma of the mental nerve clinically simulating intraosseous. J Oral Pathol Med. 35(8):517-9, 2006
                                                                                              7. Yamazaki H et al: Schwannoma of the mental nerve: usefulness of preoperative imaging: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(1):122-6, 2004
                                                                                              8. Al-Mefty O et al: Trigeminal schwannomas: removal of dumbbell-shaped tumors through the expanded Meckel cave and outcomes of cranial nerve function. J Neurosurg. 96(3):453-63, 2002
                                                                                              9. Go JL et al: The trigeminal nerve. Semin Ultrasound CT MR. 22(6):502-20, 2001
                                                                                              10. Martinoli C et al: Ultrasonography of peripheral nerves. Semin Ultrasound CT MR. 21(3):205-13, 2000
                                                                                              11. Mostafapour SP et al: Tumors and tumorous masses presenting as temporomandibular joint syndrome. Otolaryngol Head Neck Surg. 123(4):459-64, 2000
                                                                                              12. Schisano G: Stereotactic radiosurgery for trigeminal schwannomas. Neurosurgery. 46(4):1025-6, 2000
                                                                                              13. Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
                                                                                              14. Majoie CB et al: Primary nerve-sheath tumours of the trigeminal nerve: clinical and MRI findings. Neuroradiology. 41(2):100-8, 1999
                                                                                              15. Sim RJ et al: Trigeminal neurinoma presenting with trismus. J Laryngol Otol. 113(12):1112-3, 1999
                                                                                              16. Torossian JM et al: Extracranial cephalic schwannomas: a series of 15 patients. J Craniofac Surg. 10(5):389-94, 1999
                                                                                              17. Krishnamurthy S et al: Schwannomas limited to the infratemporal fossa: report of two cases. J Neurooncol. 36(3):269-77, 1998
                                                                                              18. Konovalov AN et al: Trigeminal neurinomas. A series of 111 surgical cases from a single institution. Acta Neurochir (Wien). 138(9):1027-35, 1996
                                                                                              19. Nemzek WR: The trigeminal nerve. Top Magn Reson Imaging. 8(3):132-54, 1996
                                                                                              20. Aspestrand F et al: CT and MR imaging of primary tumors of the masticator space. Acta Radiol. 33(6):518-22, 1992
                                                                                              21. Marsot-Dupuch K et al: Mandibular nerve: MR versus CT about 10 proved unusual tumors. Neuroradiology. 32(6):492-6, 1990
                                                                                              22. Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
                                                                                              23. Pollack IF et al: Neurilemomas of the trigeminal nerve. J Neurosurg. 70(5):737-45, 1989