Masticator space (MS) CNV3 (mandibular branch, trigeminal nerve) schwannoma
Synonyms
Neuroma, neurilemmoma, neurinoma
Definitions
Encapsulated tumor of Schwann cell, which displaces rather than infiltrates fascicles of CNV3 in MS
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Surgical Classification by Location
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Hsu PY et al: Huge trigeminal ancient schwannoma involving both mandible and parapharyngeal space. Ear Nose Throat J. 100(6):NP313-5, 2021
Bhowmik B et al: Evaluation of cystic schwannoma of masticator space - a case report. J Family Med Prim Care. 8(1):285-8, 2019
Mortazavi H et al: Common conditions associated with mandibular canal widening: a literature review. Imaging Sci Dent. 49(2):87-95, 2019
Perkins D et al: Intraosseous schwannoma of the jaws: an updated review of the literature and report of 2 new cases affecting the mandible. J Oral Maxillofac Surg. 76(6):1226-47, 2018
Agrawal A et al: Trigeminal schwannoma. Natl J Maxillofac Surg. 8(2):149-52, 2017
Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
Chen LF et al: Operative management of trigeminal neuromas: an analysis of a surgical experience with 55 cases. Acta Neurochir (Wien). 156(6):1105-14, 2014
Buric N et al: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol. 38(3):178-81, 2009
Baranović M et al: Schwannoma with secondary erosion of mandible: case report with a review of the literature. Dentomaxillofac Radiol. 35(6):456-60, 2006
Kowatsch E et al: Extraosseous schwannoma of the mental nerve clinically simulating intraosseous. J Oral Pathol Med. 35(8):517-9, 2006
Yamazaki H et al: Schwannoma of the mental nerve: usefulness of preoperative imaging: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(1):122-6, 2004
Al-Mefty O et al: Trigeminal schwannomas: removal of dumbbell-shaped tumors through the expanded Meckel cave and outcomes of cranial nerve function. J Neurosurg. 96(3):453-63, 2002
Go JL et al: The trigeminal nerve. Semin Ultrasound CT MR. 22(6):502-20, 2001
Martinoli C et al: Ultrasonography of peripheral nerves. Semin Ultrasound CT MR. 21(3):205-13, 2000
Mostafapour SP et al: Tumors and tumorous masses presenting as temporomandibular joint syndrome. Otolaryngol Head Neck Surg. 123(4):459-64, 2000
Schisano G: Stereotactic radiosurgery for trigeminal schwannomas. Neurosurgery. 46(4):1025-6, 2000
Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
Majoie CB et al: Primary nerve-sheath tumours of the trigeminal nerve: clinical and MRI findings. Neuroradiology. 41(2):100-8, 1999
Sim RJ et al: Trigeminal neurinoma presenting with trismus. J Laryngol Otol. 113(12):1112-3, 1999
Torossian JM et al: Extracranial cephalic schwannomas: a series of 15 patients. J Craniofac Surg. 10(5):389-94, 1999
Krishnamurthy S et al: Schwannomas limited to the infratemporal fossa: report of two cases. J Neurooncol. 36(3):269-77, 1998
Konovalov AN et al: Trigeminal neurinomas. A series of 111 surgical cases from a single institution. Acta Neurochir (Wien). 138(9):1027-35, 1996
Nemzek WR: The trigeminal nerve. Top Magn Reson Imaging. 8(3):132-54, 1996
Aspestrand F et al: CT and MR imaging of primary tumors of the masticator space. Acta Radiol. 33(6):518-22, 1992
Marsot-Dupuch K et al: Mandibular nerve: MR versus CT about 10 proved unusual tumors. Neuroradiology. 32(6):492-6, 1990
Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
Pollack IF et al: Neurilemomas of the trigeminal nerve. J Neurosurg. 70(5):737-45, 1989
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Masticator space (MS) CNV3 (mandibular branch, trigeminal nerve) schwannoma
Synonyms
Neuroma, neurilemmoma, neurinoma
Definitions
Encapsulated tumor of Schwann cell, which displaces rather than infiltrates fascicles of CNV3 in MS
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Surgical Classification by Location
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Hsu PY et al: Huge trigeminal ancient schwannoma involving both mandible and parapharyngeal space. Ear Nose Throat J. 100(6):NP313-5, 2021
Bhowmik B et al: Evaluation of cystic schwannoma of masticator space - a case report. J Family Med Prim Care. 8(1):285-8, 2019
Mortazavi H et al: Common conditions associated with mandibular canal widening: a literature review. Imaging Sci Dent. 49(2):87-95, 2019
Perkins D et al: Intraosseous schwannoma of the jaws: an updated review of the literature and report of 2 new cases affecting the mandible. J Oral Maxillofac Surg. 76(6):1226-47, 2018
Agrawal A et al: Trigeminal schwannoma. Natl J Maxillofac Surg. 8(2):149-52, 2017
Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015
Chen LF et al: Operative management of trigeminal neuromas: an analysis of a surgical experience with 55 cases. Acta Neurochir (Wien). 156(6):1105-14, 2014
Buric N et al: Mandible schwannoma (neurilemmoma) presenting as periapical lesion. Dentomaxillofac Radiol. 38(3):178-81, 2009
Baranović M et al: Schwannoma with secondary erosion of mandible: case report with a review of the literature. Dentomaxillofac Radiol. 35(6):456-60, 2006
Kowatsch E et al: Extraosseous schwannoma of the mental nerve clinically simulating intraosseous. J Oral Pathol Med. 35(8):517-9, 2006
Yamazaki H et al: Schwannoma of the mental nerve: usefulness of preoperative imaging: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 97(1):122-6, 2004
Al-Mefty O et al: Trigeminal schwannomas: removal of dumbbell-shaped tumors through the expanded Meckel cave and outcomes of cranial nerve function. J Neurosurg. 96(3):453-63, 2002
Go JL et al: The trigeminal nerve. Semin Ultrasound CT MR. 22(6):502-20, 2001
Martinoli C et al: Ultrasonography of peripheral nerves. Semin Ultrasound CT MR. 21(3):205-13, 2000
Mostafapour SP et al: Tumors and tumorous masses presenting as temporomandibular joint syndrome. Otolaryngol Head Neck Surg. 123(4):459-64, 2000
Schisano G: Stereotactic radiosurgery for trigeminal schwannomas. Neurosurgery. 46(4):1025-6, 2000
Abdel Aziz KM et al: Primary lymphoma of Meckel's cave mimicking trigeminal schwannoma: case report. Neurosurgery. 44(4):859-62; discussion 862-3, 1999
Majoie CB et al: Primary nerve-sheath tumours of the trigeminal nerve: clinical and MRI findings. Neuroradiology. 41(2):100-8, 1999
Sim RJ et al: Trigeminal neurinoma presenting with trismus. J Laryngol Otol. 113(12):1112-3, 1999
Torossian JM et al: Extracranial cephalic schwannomas: a series of 15 patients. J Craniofac Surg. 10(5):389-94, 1999
Krishnamurthy S et al: Schwannomas limited to the infratemporal fossa: report of two cases. J Neurooncol. 36(3):269-77, 1998
Konovalov AN et al: Trigeminal neurinomas. A series of 111 surgical cases from a single institution. Acta Neurochir (Wien). 138(9):1027-35, 1996
Nemzek WR: The trigeminal nerve. Top Magn Reson Imaging. 8(3):132-54, 1996
Aspestrand F et al: CT and MR imaging of primary tumors of the masticator space. Acta Radiol. 33(6):518-22, 1992
Marsot-Dupuch K et al: Mandibular nerve: MR versus CT about 10 proved unusual tumors. Neuroradiology. 32(6):492-6, 1990
Tryhus MR et al: The normal and diseased masticator space. Semin Ultrasound CT MR. 11(6):476-85, 1990
Pollack IF et al: Neurilemomas of the trigeminal nerve. J Neurosurg. 70(5):737-45, 1989
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