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Mastocytosis
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Heterogeneous neoplastic disorder that results from clonal mast cell proliferation in various organs

        IMAGING

        • General Features

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  CLINICAL ISSUES

                  • Presentation

                    • Demographics

                      • Natural History & Prognosis

                        • Treatment

                          Selected References

                          1. Alpay Kanıtez N et al: Osteoporosis and osteopathy markers in patients with mastocytosis. Turk J Haematol. 32(1):43-50, 2015
                          2. Arock M et al: Current treatment options in patients with mastocytosis: status in 2015 and future perspectives. Eur J Haematol. ePub, 2015
                          3. Gasljevic G et al: Hodgkin's lymphoma is a rare form of clonal haematological non-mast cell disease in systemic mastocytosis. Diagn Pathol. 10(1):5, 2015
                          4. Pardanani A: Systemic mastocytosis in adults: 2015 update on diagnosis, risk stratification, and management. Am J Hematol. 90(3):250-62, 2015
                          5. Fritz J et al: Advanced imaging of skeletal manifestations of systemic mastocytosis. Skeletal Radiol. 41(8):887-97, 2012
                          6. Bains SN et al: Current approaches to the diagnosis and treatment of systemic mastocytosis. Ann Allergy Asthma Immunol. 104(1):1-10; quiz 10-2, 41, 2010
                          7. Pardanani A et al: Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature. Curr Opin Hematol. 17(2):125-32, 2010
                          8. Krüger A et al: Multimodal therapy for vertebral involvement of systemic mastocytosis. Spine (Phila Pa 1976). 34(17):E626-8, 2009
                          9. Lim KH et al: Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood. 113(23):5727-36, 2009
                          10. Mathew R et al: Systemic mastocytosis presenting as osteoporosis--a case report. Clin Rheumatol. 28(7):865-6, 2009
                          11. Nguyen BD: CT and scintigraphy of aggressive lymphadenopathic mastocytosis. AJR Am J Roentgenol. 178(3):769-70, 2002
                          12. Zettinig G et al: FDG positron emission tomography in patients with systemic mastocytosis. AJR Am J Roentgenol. 179(5):1235-7, 2002
                          13. Avila NA et al: Systemic mastocytosis: CT and US features of abdominal manifestations. Radiology. 202(2):367-72, 1997
                          Related Anatomy
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                          Related Differential Diagnoses
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Terminology

                            • Imaging

                              • Clinical Issues

                                TERMINOLOGY

                                • Definitions

                                  • Heterogeneous neoplastic disorder that results from clonal mast cell proliferation in various organs

                                IMAGING

                                • General Features

                                  • Radiographic Findings

                                    • CT Findings

                                      • MR Findings

                                        • Nuclear Medicine Findings

                                          CLINICAL ISSUES

                                          • Presentation

                                            • Demographics

                                              • Natural History & Prognosis

                                                • Treatment

                                                  Selected References

                                                  1. Alpay Kanıtez N et al: Osteoporosis and osteopathy markers in patients with mastocytosis. Turk J Haematol. 32(1):43-50, 2015
                                                  2. Arock M et al: Current treatment options in patients with mastocytosis: status in 2015 and future perspectives. Eur J Haematol. ePub, 2015
                                                  3. Gasljevic G et al: Hodgkin's lymphoma is a rare form of clonal haematological non-mast cell disease in systemic mastocytosis. Diagn Pathol. 10(1):5, 2015
                                                  4. Pardanani A: Systemic mastocytosis in adults: 2015 update on diagnosis, risk stratification, and management. Am J Hematol. 90(3):250-62, 2015
                                                  5. Fritz J et al: Advanced imaging of skeletal manifestations of systemic mastocytosis. Skeletal Radiol. 41(8):887-97, 2012
                                                  6. Bains SN et al: Current approaches to the diagnosis and treatment of systemic mastocytosis. Ann Allergy Asthma Immunol. 104(1):1-10; quiz 10-2, 41, 2010
                                                  7. Pardanani A et al: Systemic mastocytosis in adults: a review on prognosis and treatment based on 342 Mayo Clinic patients and current literature. Curr Opin Hematol. 17(2):125-32, 2010
                                                  8. Krüger A et al: Multimodal therapy for vertebral involvement of systemic mastocytosis. Spine (Phila Pa 1976). 34(17):E626-8, 2009
                                                  9. Lim KH et al: Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood. 113(23):5727-36, 2009
                                                  10. Mathew R et al: Systemic mastocytosis presenting as osteoporosis--a case report. Clin Rheumatol. 28(7):865-6, 2009
                                                  11. Nguyen BD: CT and scintigraphy of aggressive lymphadenopathic mastocytosis. AJR Am J Roentgenol. 178(3):769-70, 2002
                                                  12. Zettinig G et al: FDG positron emission tomography in patients with systemic mastocytosis. AJR Am J Roentgenol. 179(5):1235-7, 2002
                                                  13. Avila NA et al: Systemic mastocytosis: CT and US features of abdominal manifestations. Radiology. 202(2):367-72, 1997