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KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Systemic mastocytosis (SM)
Synonyms
- Systemic mast cell disease
Definitions
- Rare disorder characterized by mast cell proliferation in skin, bones, lymph nodes, and abdominal viscera
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Hanafy AK et al: Hematologic malignancies of the gastrointestinal luminal tract. Abdom Radiol (NY). 45(10):3007-27, 2020
- Ozturk K et al: Non-hematologic diagnosis of systemic mastocytosis: collaboration of radiology and pathology. Blood Rev. 100693, 2020
- Bonadonna P et al: Mastocytosis and allergic diseases. J Investig Allergol Clin Immunol. 24(5):288-97; quiz 3 p preceding 297, 2014
- Ustun C et al: Hematopoietic stem-cell transplantation for advanced systemic mastocytosis. J Clin Oncol. 32(29):3264-74, 2014
- Doyle LA et al: A clinicopathologic study of 24 cases of systemic mastocytosis involving the gastrointestinal tract and assessment of mucosal mast cell density in irritable bowel syndrome and asymptomatic patients. Am J Surg Pathol. 38(6):832-43, 2014
- Black JS et al: Systemic mastocytosis as a rare cause of diffuse gastrointestinal hemorrhage. Am Surg. 75(5):429-30, 2009
- Butterfield JH: Survey of aspirin administration in systemic mastocytosis. Prostaglandins Other Lipid Mediat. 88(3-4):122-4, 2009
- Lim KH et al: Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood. 113(23):5727-36, 2009
- Vannucchi AM et al: Advances in understanding and management of myeloproliferative neoplasms. CA Cancer J Clin. 59(3):171-91, 2009
- Avila NA et al: Systemic mastocytosis: CT and US features of abdominal manifestations. Radiology. 202(2):367-72, 1997
- Metcalfe DD: The liver, spleen, and lymph nodes in mastocytosis. J Invest Dermatol. 96(3):45S-6S, 1991
- Johnson AC et al: Systemic mastocytosis and mastocytosis-like syndrome: radiologic features of gastrointestinal manifestations. South Med J. 81(6):729-33, 750, 1988
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Systemic mastocytosis (SM)
Synonyms
- Systemic mast cell disease
Definitions
- Rare disorder characterized by mast cell proliferation in skin, bones, lymph nodes, and abdominal viscera
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Hanafy AK et al: Hematologic malignancies of the gastrointestinal luminal tract. Abdom Radiol (NY). 45(10):3007-27, 2020
- Ozturk K et al: Non-hematologic diagnosis of systemic mastocytosis: collaboration of radiology and pathology. Blood Rev. 100693, 2020
- Bonadonna P et al: Mastocytosis and allergic diseases. J Investig Allergol Clin Immunol. 24(5):288-97; quiz 3 p preceding 297, 2014
- Ustun C et al: Hematopoietic stem-cell transplantation for advanced systemic mastocytosis. J Clin Oncol. 32(29):3264-74, 2014
- Doyle LA et al: A clinicopathologic study of 24 cases of systemic mastocytosis involving the gastrointestinal tract and assessment of mucosal mast cell density in irritable bowel syndrome and asymptomatic patients. Am J Surg Pathol. 38(6):832-43, 2014
- Black JS et al: Systemic mastocytosis as a rare cause of diffuse gastrointestinal hemorrhage. Am Surg. 75(5):429-30, 2009
- Butterfield JH: Survey of aspirin administration in systemic mastocytosis. Prostaglandins Other Lipid Mediat. 88(3-4):122-4, 2009
- Lim KH et al: Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors. Blood. 113(23):5727-36, 2009
- Vannucchi AM et al: Advances in understanding and management of myeloproliferative neoplasms. CA Cancer J Clin. 59(3):171-91, 2009
- Avila NA et al: Systemic mastocytosis: CT and US features of abdominal manifestations. Radiology. 202(2):367-72, 1997
- Metcalfe DD: The liver, spleen, and lymph nodes in mastocytosis. J Invest Dermatol. 96(3):45S-6S, 1991
- Johnson AC et al: Systemic mastocytosis and mastocytosis-like syndrome: radiologic features of gastrointestinal manifestations. South Med J. 81(6):729-33, 750, 1988
