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Mature Cystic Teratoma (Dermoid Cyst)
Akram M. Shaaban, MBBCh
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Dermoid cyst
            • Mature cystic teratoma
          • Definitions

            • Mature teratoma: Tumor composed exclusively of mature tissues derived from 2 or 3 germ layers (ectoderm, mesoderm, &/or endoderm)
            • Classified as benign ovarian germ cell tumor

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging of Complications

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          • Complications

                            • Pathogenesis

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Srisajjakul S et al: Imaging features of unusual lesions and complications associated with ovarian mature cystic teratoma. Clin Imaging. 57:115-23, 2019
                                        2. Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
                                        3. Chaudhry S et al: Squamous cell carcinoma arising in mature cystic teratoma (dermoid cyst)--a rare presentation. J Pak Med Assoc. 63(4):521-3, 2013
                                        4. Momtahen A et al: Mature ovarian cystic teratoma (dermoid cyst). Ultrasound Q. 28(3):175-7, 2012
                                        5. Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
                                        6. Luk J et al: The superinfection of a dermoid cyst. Infect Dis Obstet Gynecol. 2007:41473, 2007
                                        7. Rim SY et al: Malignant transformation of ovarian mature cystic teratoma. Int J Gynecol Cancer. 16(1):140-4, 2006
                                        8. Yazici B et al: Floating ball appearance in ovarian cystic teratoma. Diagn Interv Radiol. 12(3):136-8, 2006
                                        9. Zagame L et al: Growing teratoma syndrome after ovarian germ cell tumors. Obstet Gynecol. 108(3 Pt 1):509-14, 2006
                                        10. Nakayama T et al: Diffusion-weighted echo-planar MR imaging and ADC mapping in the differential diagnosis of ovarian cystic masses: usefulness of detecting keratinoid substances in mature cystic teratomas. J Magn Reson Imaging. 22(2):271-8, 2005
                                        11. Pereira JM et al: CT and MR imaging of extrahepatic fatty masses of the abdomen and pelvis: techniques, diagnosis, differential diagnosis, and pitfalls. Radiographics. 25(1):69-85, 2005
                                        12. Wootton-Gorges SL et al: Giant cystic abdominal masses in children. Pediatr Radiol. 35(12):1277-88, 2005
                                        13. Kim KA et al: Benign ovarian tumors with solid and cystic components that mimic malignancy. AJR Am J Roentgenol. 182(5):1259-65, 2004
                                        14. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                        15. Kim HC et al: Fluid-fluid levels in ovarian teratomas. Abdom Imaging. 27(1):100-5, 2002
                                        16. Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
                                        17. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Dermoid cyst
                                                  • Mature cystic teratoma
                                                • Definitions

                                                  • Mature teratoma: Tumor composed exclusively of mature tissues derived from 2 or 3 germ layers (ectoderm, mesoderm, &/or endoderm)
                                                  • Classified as benign ovarian germ cell tumor

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        • Imaging of Complications

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                • Complications

                                                                  • Pathogenesis

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Srisajjakul S et al: Imaging features of unusual lesions and complications associated with ovarian mature cystic teratoma. Clin Imaging. 57:115-23, 2019
                                                                              2. Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
                                                                              3. Chaudhry S et al: Squamous cell carcinoma arising in mature cystic teratoma (dermoid cyst)--a rare presentation. J Pak Med Assoc. 63(4):521-3, 2013
                                                                              4. Momtahen A et al: Mature ovarian cystic teratoma (dermoid cyst). Ultrasound Q. 28(3):175-7, 2012
                                                                              5. Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
                                                                              6. Luk J et al: The superinfection of a dermoid cyst. Infect Dis Obstet Gynecol. 2007:41473, 2007
                                                                              7. Rim SY et al: Malignant transformation of ovarian mature cystic teratoma. Int J Gynecol Cancer. 16(1):140-4, 2006
                                                                              8. Yazici B et al: Floating ball appearance in ovarian cystic teratoma. Diagn Interv Radiol. 12(3):136-8, 2006
                                                                              9. Zagame L et al: Growing teratoma syndrome after ovarian germ cell tumors. Obstet Gynecol. 108(3 Pt 1):509-14, 2006
                                                                              10. Nakayama T et al: Diffusion-weighted echo-planar MR imaging and ADC mapping in the differential diagnosis of ovarian cystic masses: usefulness of detecting keratinoid substances in mature cystic teratomas. J Magn Reson Imaging. 22(2):271-8, 2005
                                                                              11. Pereira JM et al: CT and MR imaging of extrahepatic fatty masses of the abdomen and pelvis: techniques, diagnosis, differential diagnosis, and pitfalls. Radiographics. 25(1):69-85, 2005
                                                                              12. Wootton-Gorges SL et al: Giant cystic abdominal masses in children. Pediatr Radiol. 35(12):1277-88, 2005
                                                                              13. Kim KA et al: Benign ovarian tumors with solid and cystic components that mimic malignancy. AJR Am J Roentgenol. 182(5):1259-65, 2004
                                                                              14. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                                                              15. Kim HC et al: Fluid-fluid levels in ovarian teratomas. Abdom Imaging. 27(1):100-5, 2002
                                                                              16. Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
                                                                              17. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000