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Maxillary Sinus Hypoplasia/Aplasia
Axel Ruprecht, DDS, MScD, FRCD(C)
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Frontal sinus hypoplasia/aplasia (FSH/FSA)
              • Maxillary sinus hypoplasia/aplasia (MSH/MSA)
            • Synonyms

              • Hypogenesis/agenesis of specific sinuses &/or nasal fossae (NF)
            • Definitions

              • Underdevelopment or lack of development of frontal sinus(es) (FS), ethmoid air cells [sinus(es)], sphenoid sinus(es), or maxillary sinus(es) (MS), &/or NF

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Martínez-Capoccioni G et al: Silent sinus syndrome an acquired condition and the essential role of otorhinolaryngologist consultation: a retrospective study. Eur Arch Otorhinolaryngol. 273(10):3183-8, 2016
                                          2. Angulo-Pérez G et al: [Prevalence, location and tomographic severity of chronic rhinosinusitis in adult patients with common variable immunodeficiency.] Rev Alerg Mex. 62(1):15-21, 2015
                                          3. Demir UL et al: Anatomical correlation between existence of concha bullosa and maxillary sinus volume. Surg Radiol Anat. 37(9):1093-8, 2015
                                          4. Göçmen G et al: Effect of septal deviation, concha bullosa and Haller's cell on maxillary sinus's inferior pneumatization; a retrospective study. Open Dent J. 9:282-6, 2015
                                          5. Selcuk OT et al: Do altitude and climate affect paranasal sinus volume? J Craniomaxillofac Surg. 43(7):1059-64, 2015
                                          6. Chrcanovic BR et al: Maxillary sinus aplasia. Oral Maxillofac Surg. 14(3):187-91, 2010
                                          7. Güven DG et al: Combined aplasia of sphenoid, frontal, and maxillary sinuses accompanied by ethmoid sinus hypoplasia. J Craniofac Surg. 21(5):1431-3, 2010
                                          8. Whyte MP et al: Dysosteosclerosis presents as an "osteoclast-poor" form of osteopetrosis: comprehensive investigation of a 3-year-old girl and literature review. J Bone Miner Res. 25(11):2527-39, 2010
                                          9. Nagasao T et al: A rare case of congenital unilateral hypoplasia of the nose. J Plast Reconstr Aesthet Surg. 62(9):e305-8, 2009
                                          10. Song SY et al: Volume and distances of the maxillary sinus in craniofacial deformities with midfacial hypoplasia. Otolaryngol Head Neck Surg. 141(5):614-20, 2009
                                          11. Garg RK et al: Clinical spectrum of cleidocranial dysplasia: a case report. Cases J. 1(1):377, 2008
                                          12. Lawson W et al: The development and pathologic processes that influence maxillary sinus pneumatization. Anat Rec (Hoboken). 291(11):1554-63, 2008
                                          13. Selcuk A et al: Variations of maxillary sinus and accompanying anatomical and pathological structures. J Craniofac Surg. 19(1):159-64, 2008
                                          14. Birkent H et al: Progressive maxillary sinus hypoplasia with open ostium. J Craniofac Surg. 18(3):706-8, 2007
                                          15. Pino Rivero V et al: [Maxillary sinus hypoplasia masquerading a chronic sinusitis.] An Otorrinolaringol Ibero Am. 34(4):323-8, 2007
                                          16. Price DL et al: Facial asymmetry in maxillary sinus hypoplasia. Int J Pediatr Otorhinolaryngol. 71(10):1627-30, 2007
                                          17. Tasar M et al: Bilateral maxillary sinus hypoplasia and aplasia: radiological and clinical findings. Dentomaxillofac Radiol. 36(7):412-5, 2007
                                          18. Woodworth BA et al: The delta F508 mutation in cystic fibrosis and impact on sinus development. Am J Rhinol. 21(1):122-7, 2007
                                          19. Hazza'a AM et al: Radiographic features of the jaws and teeth in thalassaemia major. Dentomaxillofac Radiol. 35(4):283-8, 2006
                                          20. Loehrl TA et al: The hypoplastic maxillary sinus and the orbital floor. Curr Opin Otolaryngol Head Neck Surg. 14(1):35-7, 2006
                                          21. Haktanir A et al: Combined sphenoid and frontal sinus aplasia accompanied by bilateral maxillary and ethmoid sinus hypoplasia. Br J Radiol. 78(935):1053-6, 2005
                                          22. Islam M et al: Clinical features of tricho-dento-osseous syndrome and presentation of three new cases: an addition to clinical heterogeneity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 100(6):736-42, 2005
                                          23. Aydinlioğlu A et al: Maxillary and sphenoid sinus aplasia in Turkish individuals: a retrospective review using computed tomography. Clin Anat. 17(8):618-22, 2004
                                          24. Verloes A et al: Fronto-otopalatodigital osteodysplasia: clinical evidence for a single entity encompassing Melnick-Needles syndrome, otopalatodigital syndrome types 1 and 2, and frontometaphyseal dysplasia. Am J Med Genet. 90(5):407-22, 2000
                                          25. Karabulut N et al: Obliteration of maxillary and sphenoid sinuses in Gaucher's disease. Br J Radiol. 70(833):533-5, 1997
                                          26. Khanobthamchai K et al: Ethmomaxillary sinus and hypoplasia of maxillary sinus. J Otolaryngol. 20(6):425-7, 1991
                                          27. Bolger WE et al: Maxillary sinus hypoplasia: classification and description of associated uncinate process hypoplasia. Otolaryngol Head Neck Surg. 103(5 ( Pt 1)):759-65, 1990
                                          28. Barone GW et al: Endothelial injury and vascular dysfunction associated with the Fogarty balloon catheter. J Vasc Surg. 9(3):422-5, 1989
                                          29. Karmody CS et al: Developmental anomalies of the maxillary sinus. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 84(4 Pt 1):ORL-723-8, 1977
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Frontal sinus hypoplasia/aplasia (FSH/FSA)
                                                      • Maxillary sinus hypoplasia/aplasia (MSH/MSA)
                                                    • Synonyms

                                                      • Hypogenesis/agenesis of specific sinuses &/or nasal fossae (NF)
                                                    • Definitions

                                                      • Underdevelopment or lack of development of frontal sinus(es) (FS), ethmoid air cells [sinus(es)], sphenoid sinus(es), or maxillary sinus(es) (MS), &/or NF

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              • Image Interpretation Pearls

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Martínez-Capoccioni G et al: Silent sinus syndrome an acquired condition and the essential role of otorhinolaryngologist consultation: a retrospective study. Eur Arch Otorhinolaryngol. 273(10):3183-8, 2016
                                                                                  2. Angulo-Pérez G et al: [Prevalence, location and tomographic severity of chronic rhinosinusitis in adult patients with common variable immunodeficiency.] Rev Alerg Mex. 62(1):15-21, 2015
                                                                                  3. Demir UL et al: Anatomical correlation between existence of concha bullosa and maxillary sinus volume. Surg Radiol Anat. 37(9):1093-8, 2015
                                                                                  4. Göçmen G et al: Effect of septal deviation, concha bullosa and Haller's cell on maxillary sinus's inferior pneumatization; a retrospective study. Open Dent J. 9:282-6, 2015
                                                                                  5. Selcuk OT et al: Do altitude and climate affect paranasal sinus volume? J Craniomaxillofac Surg. 43(7):1059-64, 2015
                                                                                  6. Chrcanovic BR et al: Maxillary sinus aplasia. Oral Maxillofac Surg. 14(3):187-91, 2010
                                                                                  7. Güven DG et al: Combined aplasia of sphenoid, frontal, and maxillary sinuses accompanied by ethmoid sinus hypoplasia. J Craniofac Surg. 21(5):1431-3, 2010
                                                                                  8. Whyte MP et al: Dysosteosclerosis presents as an "osteoclast-poor" form of osteopetrosis: comprehensive investigation of a 3-year-old girl and literature review. J Bone Miner Res. 25(11):2527-39, 2010
                                                                                  9. Nagasao T et al: A rare case of congenital unilateral hypoplasia of the nose. J Plast Reconstr Aesthet Surg. 62(9):e305-8, 2009
                                                                                  10. Song SY et al: Volume and distances of the maxillary sinus in craniofacial deformities with midfacial hypoplasia. Otolaryngol Head Neck Surg. 141(5):614-20, 2009
                                                                                  11. Garg RK et al: Clinical spectrum of cleidocranial dysplasia: a case report. Cases J. 1(1):377, 2008
                                                                                  12. Lawson W et al: The development and pathologic processes that influence maxillary sinus pneumatization. Anat Rec (Hoboken). 291(11):1554-63, 2008
                                                                                  13. Selcuk A et al: Variations of maxillary sinus and accompanying anatomical and pathological structures. J Craniofac Surg. 19(1):159-64, 2008
                                                                                  14. Birkent H et al: Progressive maxillary sinus hypoplasia with open ostium. J Craniofac Surg. 18(3):706-8, 2007
                                                                                  15. Pino Rivero V et al: [Maxillary sinus hypoplasia masquerading a chronic sinusitis.] An Otorrinolaringol Ibero Am. 34(4):323-8, 2007
                                                                                  16. Price DL et al: Facial asymmetry in maxillary sinus hypoplasia. Int J Pediatr Otorhinolaryngol. 71(10):1627-30, 2007
                                                                                  17. Tasar M et al: Bilateral maxillary sinus hypoplasia and aplasia: radiological and clinical findings. Dentomaxillofac Radiol. 36(7):412-5, 2007
                                                                                  18. Woodworth BA et al: The delta F508 mutation in cystic fibrosis and impact on sinus development. Am J Rhinol. 21(1):122-7, 2007
                                                                                  19. Hazza'a AM et al: Radiographic features of the jaws and teeth in thalassaemia major. Dentomaxillofac Radiol. 35(4):283-8, 2006
                                                                                  20. Loehrl TA et al: The hypoplastic maxillary sinus and the orbital floor. Curr Opin Otolaryngol Head Neck Surg. 14(1):35-7, 2006
                                                                                  21. Haktanir A et al: Combined sphenoid and frontal sinus aplasia accompanied by bilateral maxillary and ethmoid sinus hypoplasia. Br J Radiol. 78(935):1053-6, 2005
                                                                                  22. Islam M et al: Clinical features of tricho-dento-osseous syndrome and presentation of three new cases: an addition to clinical heterogeneity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 100(6):736-42, 2005
                                                                                  23. Aydinlioğlu A et al: Maxillary and sphenoid sinus aplasia in Turkish individuals: a retrospective review using computed tomography. Clin Anat. 17(8):618-22, 2004
                                                                                  24. Verloes A et al: Fronto-otopalatodigital osteodysplasia: clinical evidence for a single entity encompassing Melnick-Needles syndrome, otopalatodigital syndrome types 1 and 2, and frontometaphyseal dysplasia. Am J Med Genet. 90(5):407-22, 2000
                                                                                  25. Karabulut N et al: Obliteration of maxillary and sphenoid sinuses in Gaucher's disease. Br J Radiol. 70(833):533-5, 1997
                                                                                  26. Khanobthamchai K et al: Ethmomaxillary sinus and hypoplasia of maxillary sinus. J Otolaryngol. 20(6):425-7, 1991
                                                                                  27. Bolger WE et al: Maxillary sinus hypoplasia: classification and description of associated uncinate process hypoplasia. Otolaryngol Head Neck Surg. 103(5 ( Pt 1)):759-65, 1990
                                                                                  28. Barone GW et al: Endothelial injury and vascular dysfunction associated with the Fogarty balloon catheter. J Vasc Surg. 9(3):422-5, 1989
                                                                                  29. Karmody CS et al: Developmental anomalies of the maxillary sinus. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 84(4 Pt 1):ORL-723-8, 1977