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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Meconium aspiration syndrome (MAS)
Definitions
Respiratory distress in setting of aspiration of meconium-stained amniotic fluid
MAS causes ↓ lung compliance & hypoxia ± pulmonary hypertension & air leak syndrome
Severe MAS: Requires mechanical ventilation
IMAGING
General Features
Radiographic Findings
Ultrasonographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Hiersch L et al: Effect of meconium-stained amniotic fluid on perinatal complications in low-risk pregnancies at term. Am J Perinatol. 33(4):378-84, 2016
Natarajan CK et al: Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. J Perinatol. 36 Suppl 1:S49-54, 2016
Rodríguez-Fanjul J et al: Lung ultrasound as a predictor of mechanical ventilation in neonates older than 32 weeks. Neonatology. 110(3):198-203, 2016
Lindenskov PH et al: Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. Neonatology. 107(3):225-30, 2015
Duong HH et al: Pneumothorax in neonates: Trends, predictors and outcomes. J Neonatal Perinatal Med. 7(1):29-38, 2014
Hutton EK et al: Consequences of meconium stained amniotic fluid: what does the evidence tell us? Early Hum Dev. 90(7):333-9, 2014
Piastra M et al: Lung ultrasound findings in meconium aspiration syndrome. Early Hum Dev. 90 Suppl 2:S41-3, 2014
Reuter S et al: Respiratory distress in the newborn. Pediatr Rev. 35(10):417-28; quiz 429, 2014
Hofer N et al: Meconium aspiration syndrome--a 21-years' experience from a tertiary care center and analysis of risk factors for predicting disease severity. Klin Padiatr. 225(7):383-8, 2013
Mundhra R et al: Fetal outcome in meconium stained deliveries. J Clin Diagn Res. 7(12):2874-6, 2013
Fischer C et al: A population-based study of meconium aspiration syndrome in neonates born between 37 and 43 weeks of gestation. Int J Pediatr. 2012:321545, 2012
Szczapa T et al: Use of heliox in the management of neonates with meconium aspiration syndrome. Neonatology. 100(3):265-70, 2011
Vasireddy S et al: MRI and US findings of subcutaneous fat necrosis of the newborn. Pediatr Radiol. 39(1):73-6, 2009
Gelfand SL et al: Meconium stained fluid: approach to the mother and the baby. Pediatr Clin North Am. 51(3):655-67, ix, 2004
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Meconium aspiration syndrome (MAS)
Definitions
Respiratory distress in setting of aspiration of meconium-stained amniotic fluid
MAS causes ↓ lung compliance & hypoxia ± pulmonary hypertension & air leak syndrome
Severe MAS: Requires mechanical ventilation
IMAGING
General Features
Radiographic Findings
Ultrasonographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Hiersch L et al: Effect of meconium-stained amniotic fluid on perinatal complications in low-risk pregnancies at term. Am J Perinatol. 33(4):378-84, 2016
Natarajan CK et al: Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. J Perinatol. 36 Suppl 1:S49-54, 2016
Rodríguez-Fanjul J et al: Lung ultrasound as a predictor of mechanical ventilation in neonates older than 32 weeks. Neonatology. 110(3):198-203, 2016
Lindenskov PH et al: Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. Neonatology. 107(3):225-30, 2015
Duong HH et al: Pneumothorax in neonates: Trends, predictors and outcomes. J Neonatal Perinatal Med. 7(1):29-38, 2014
Hutton EK et al: Consequences of meconium stained amniotic fluid: what does the evidence tell us? Early Hum Dev. 90(7):333-9, 2014
Piastra M et al: Lung ultrasound findings in meconium aspiration syndrome. Early Hum Dev. 90 Suppl 2:S41-3, 2014
Reuter S et al: Respiratory distress in the newborn. Pediatr Rev. 35(10):417-28; quiz 429, 2014
Hofer N et al: Meconium aspiration syndrome--a 21-years' experience from a tertiary care center and analysis of risk factors for predicting disease severity. Klin Padiatr. 225(7):383-8, 2013
Mundhra R et al: Fetal outcome in meconium stained deliveries. J Clin Diagn Res. 7(12):2874-6, 2013
Fischer C et al: A population-based study of meconium aspiration syndrome in neonates born between 37 and 43 weeks of gestation. Int J Pediatr. 2012:321545, 2012
Szczapa T et al: Use of heliox in the management of neonates with meconium aspiration syndrome. Neonatology. 100(3):265-70, 2011
Vasireddy S et al: MRI and US findings of subcutaneous fat necrosis of the newborn. Pediatr Radiol. 39(1):73-6, 2009
Gelfand SL et al: Meconium stained fluid: approach to the mother and the baby. Pediatr Clin North Am. 51(3):655-67, ix, 2004
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