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Mediastinal Lymphangioma
Aletta Ann Frazier, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Lymphatic malformation
              • Definitions

                • Rare, benign tumor of lymphatic channels

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  • Immunohistochemistry

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Garrana SH et al: Imaging of the anterior/prevascular mediastinum. Radiol Clin North Am. 59(2):155-68, 2021
                                            2. Salehi F et al: Case report of a rare cystic mediastinal lymphangioma mimicking recurrent pleural effusion. Case Rep Radiol. 2019:1301845, 2019
                                            3. Zhong R et al: Application of endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal lymphangioma. Ann Transl Med. 7(18):450, 2019
                                            4. Burke AP et al: Miscellaneous mediastinal tumors. In Practical Thoracic Pathology: Diseases of the Lung, Heart and Thymus. Wolters Kluwer. 566-7, 2017
                                            5. Carter BW et al: ITMIG classification of mediastinal compartments and multidisciplinary approach to mediastinal masses. Radiographics. 37(2):413-36, 2017
                                            6. Carter BW et al: MR imaging of mediastinal masses. Top Magn Reson Imaging. 26(4):153-65, 2017
                                            7. Zhou H et al: Thoracoscopic resection of a huge mediastinal cystic lymphangioma. J Thorac Dis. 9(10):E887-9, 2017
                                            8. Itkin M et al: Nonmalignant adult thoracic lymphatic disorders. Clin Chest Med. 37(3):409-20, 2016
                                            9. Merrow AC et al: 2014 Revised classification of vascular lesions from the International Society for the Study of Vascular Anomalies: radiologic-pathologic update. Radiographics. 36(5):1494-516, 2016
                                            10. Swarnakar RN et al: A 36-year-old female with recurrent left sided pleural effusion: a rare case of mediastinal lymphangioma. Am J Case Rep. 17:799-804, 2016
                                            11. Raman SP et al: Imaging of thoracic lymphatic diseases. AJR Am J Roentgenol. 193(6):1504-13, 2009
                                            12. Agarwal PP et al: Case 130: mediastinal hemangioma. Radiology. 246(2):634-7, 2008
                                            13. Duwe BV et al: Tumors of the mediastinum. Chest. 128(4):2893-909, 2005
                                            14. Jeung MY et al: Imaging of cystic masses of the mediastinum. Radiographics. 22 Spec No:S79-93, 2002
                                            15. Faul JL et al: Thoracic lymphangiomas, lymphangiectasis, lymphangiomatosis, and lymphatic dysplasia syndrome. Am J Respir Crit Care Med. 161(3 Pt 1):1037-46, 2000
                                            16. Shaffer K et al: Thoracic lymphangioma in adults: CT and MR imaging features. AJR Am J Roentgenol. 162(2):283-9, 1994
                                            17. Zadvinskis DP et al: Congenital malformations of the cervicothoracic lymphatic system: embryology and pathogenesis. Radiographics. 12(6):1175-89, 1992
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Synonyms

                                                          • Lymphatic malformation
                                                        • Definitions

                                                          • Rare, benign tumor of lymphatic channels

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            • Immunohistochemistry

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Garrana SH et al: Imaging of the anterior/prevascular mediastinum. Radiol Clin North Am. 59(2):155-68, 2021
                                                                                      2. Salehi F et al: Case report of a rare cystic mediastinal lymphangioma mimicking recurrent pleural effusion. Case Rep Radiol. 2019:1301845, 2019
                                                                                      3. Zhong R et al: Application of endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal lymphangioma. Ann Transl Med. 7(18):450, 2019
                                                                                      4. Burke AP et al: Miscellaneous mediastinal tumors. In Practical Thoracic Pathology: Diseases of the Lung, Heart and Thymus. Wolters Kluwer. 566-7, 2017
                                                                                      5. Carter BW et al: ITMIG classification of mediastinal compartments and multidisciplinary approach to mediastinal masses. Radiographics. 37(2):413-36, 2017
                                                                                      6. Carter BW et al: MR imaging of mediastinal masses. Top Magn Reson Imaging. 26(4):153-65, 2017
                                                                                      7. Zhou H et al: Thoracoscopic resection of a huge mediastinal cystic lymphangioma. J Thorac Dis. 9(10):E887-9, 2017
                                                                                      8. Itkin M et al: Nonmalignant adult thoracic lymphatic disorders. Clin Chest Med. 37(3):409-20, 2016
                                                                                      9. Merrow AC et al: 2014 Revised classification of vascular lesions from the International Society for the Study of Vascular Anomalies: radiologic-pathologic update. Radiographics. 36(5):1494-516, 2016
                                                                                      10. Swarnakar RN et al: A 36-year-old female with recurrent left sided pleural effusion: a rare case of mediastinal lymphangioma. Am J Case Rep. 17:799-804, 2016
                                                                                      11. Raman SP et al: Imaging of thoracic lymphatic diseases. AJR Am J Roentgenol. 193(6):1504-13, 2009
                                                                                      12. Agarwal PP et al: Case 130: mediastinal hemangioma. Radiology. 246(2):634-7, 2008
                                                                                      13. Duwe BV et al: Tumors of the mediastinum. Chest. 128(4):2893-909, 2005
                                                                                      14. Jeung MY et al: Imaging of cystic masses of the mediastinum. Radiographics. 22 Spec No:S79-93, 2002
                                                                                      15. Faul JL et al: Thoracic lymphangiomas, lymphangiectasis, lymphangiomatosis, and lymphatic dysplasia syndrome. Am J Respir Crit Care Med. 161(3 Pt 1):1037-46, 2000
                                                                                      16. Shaffer K et al: Thoracic lymphangioma in adults: CT and MR imaging features. AJR Am J Roentgenol. 162(2):283-9, 1994
                                                                                      17. Zadvinskis DP et al: Congenital malformations of the cervicothoracic lymphatic system: embryology and pathogenesis. Radiographics. 12(6):1175-89, 1992