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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Non-Hodgkin lymphoma (NHL)
Hodgkin lymphoma (HL)
Synonyms
Primary mediastinal lymphoma
Definitions
Lymphoma arising primarily within or secondarily involving mediastinum
Primary mediastinal lymphomas
Rare, comprise approximately 1% of all lymphomas; most common primary mediastinal malignancies
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Pfau D et al: Primary Mediastinal large B-cell lymphoma: a review for radiologists. AJR Am J Roentgenol. 213(5):W194-210, 2019
Ceriani L et al: Positron emission tomography/computed tomography assessment after immunochemotherapy and irradiation using the Lugano classification criteria in the IELSG-26 study of primary mediastinal B-cell lymphoma. Int J Radiat Oncol Biol Phys. 97(1):42-9, 2017
Kligerman SJ et al: Primary extranodal lymphoma of the thorax. Radiol Clin North Am. 54(4):673-87, 2016
Verma A et al: Mediastinal gray zone lymphoma: a wider category than we think? Int J Surg Pathol. 24(5):382-93, 2016
Zinzani PL et al: Optimizing outcomes in primary mediastinal B-cell lymphoma. Hematol Oncol Clin North Am. 30(6):1261-75, 2016
Carter BW et al: Multimodality imaging of cardiothoracic lymphoma. Eur J Radiol. 83(8):1470-82, 2014
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Non-Hodgkin lymphoma (NHL)
Hodgkin lymphoma (HL)
Synonyms
Primary mediastinal lymphoma
Definitions
Lymphoma arising primarily within or secondarily involving mediastinum
Primary mediastinal lymphomas
Rare, comprise approximately 1% of all lymphomas; most common primary mediastinal malignancies
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Pfau D et al: Primary Mediastinal large B-cell lymphoma: a review for radiologists. AJR Am J Roentgenol. 213(5):W194-210, 2019
Ceriani L et al: Positron emission tomography/computed tomography assessment after immunochemotherapy and irradiation using the Lugano classification criteria in the IELSG-26 study of primary mediastinal B-cell lymphoma. Int J Radiat Oncol Biol Phys. 97(1):42-9, 2017
Kligerman SJ et al: Primary extranodal lymphoma of the thorax. Radiol Clin North Am. 54(4):673-87, 2016
Verma A et al: Mediastinal gray zone lymphoma: a wider category than we think? Int J Surg Pathol. 24(5):382-93, 2016
Zinzani PL et al: Optimizing outcomes in primary mediastinal B-cell lymphoma. Hematol Oncol Clin North Am. 30(6):1261-75, 2016
Carter BW et al: Multimodality imaging of cardiothoracic lymphoma. Eur J Radiol. 83(8):1470-82, 2014
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