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Mediastinal Non-Hodgkin Lymphoma
Santiago Martínez-Jiménez, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Non-Hodgkin lymphoma (NHL)
            • Definitions

              • Any lymphatic malignancy other than Hodgkin lymphoma (HL)
              • Frequently involves thorax as part of diffuse disease or primary mediastinal lymphoma

            IMAGING

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Barrington SF et al: Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol. 32(27):3048-58, 2014
                                  2. Cheson BD et al: Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 32(27):3059-68, 2014
                                  3. Santos FP et al: Small lymphocytic lymphoma and chronic lymphocytic leukemia: are they the same disease? Cancer J. 18(5):396-403, 2012
                                  4. Cronin CG et al: Clinical utility of PET/CT in lymphoma. AJR Am J Roentgenol. 194(1):W91-W103, 2010
                                  5. Johnson PW et al: Primary mediastinal B-cell lymphoma. Hematology Am Soc Hematol Educ Program. 2008:349-58, 2008
                                  6. Juweid ME et al: Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma. J Clin Oncol. 25(5):571-8, 2007
                                  7. Tateishi U et al: Primary mediastinal lymphoma: characteristic features of the various histological subtypes on CT. J Comput Assist Tomogr. 28(6):782-9, 2004
                                  8. Castellino RA et al: Non-Hodgkin lymphoma: contribution of chest CT in the initial staging evaluation. Radiology. 199(1):129-32, 1996
                                  9. Castellino RA: The non-Hodgkin lymphomas: practical concepts for the diagnostic radiologist. Radiology. 178(2):315-21, 1991
                                  10. Rehn SM et al: Non-Hodgkin lymphoma: predicting prognostic grade with MR imaging. Radiology. 176(1):249-53, 1990
                                  11. Blank N et al: The mediastinum in Hodgkin's and non-Hodgkin's lymphomas. J Thorac Imaging. 2(1):66-71, 1987
                                  12. Bragg DG et al: New concepts in the non-Hodgkin lymphomas: radiologic implications. Radiology. 159(2):291-304, 1986
                                  13. Khoury MB et al: Role of chest CT in non-Hodgkin lymphoma. Radiology. 158(3):659-62, 1986
                                  14. Press GA et al: Thoracic wall involvement by Hodgkin disease and non-Hodgkin lymphoma: CT evaluation. Radiology. 157(1):195-8, 1985
                                  15. Filly R et al: Radiographic distribution of intrathoracic disease in previously untreated patients with Hodgkin's disease and non-Hodgkin's lymphoma. Radiology. 120(2):277-81, 1976
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Non-Hodgkin lymphoma (NHL)
                                            • Definitions

                                              • Any lymphatic malignancy other than Hodgkin lymphoma (HL)
                                              • Frequently involves thorax as part of diffuse disease or primary mediastinal lymphoma

                                            IMAGING

                                            • Radiographic Findings

                                              • CT Findings

                                                • MR Findings

                                                  • Nuclear Medicine Findings

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Staging, Grading, & Classification

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Barrington SF et al: Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol. 32(27):3048-58, 2014
                                                                  2. Cheson BD et al: Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 32(27):3059-68, 2014
                                                                  3. Santos FP et al: Small lymphocytic lymphoma and chronic lymphocytic leukemia: are they the same disease? Cancer J. 18(5):396-403, 2012
                                                                  4. Cronin CG et al: Clinical utility of PET/CT in lymphoma. AJR Am J Roentgenol. 194(1):W91-W103, 2010
                                                                  5. Johnson PW et al: Primary mediastinal B-cell lymphoma. Hematology Am Soc Hematol Educ Program. 2008:349-58, 2008
                                                                  6. Juweid ME et al: Use of positron emission tomography for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project in Lymphoma. J Clin Oncol. 25(5):571-8, 2007
                                                                  7. Tateishi U et al: Primary mediastinal lymphoma: characteristic features of the various histological subtypes on CT. J Comput Assist Tomogr. 28(6):782-9, 2004
                                                                  8. Castellino RA et al: Non-Hodgkin lymphoma: contribution of chest CT in the initial staging evaluation. Radiology. 199(1):129-32, 1996
                                                                  9. Castellino RA: The non-Hodgkin lymphomas: practical concepts for the diagnostic radiologist. Radiology. 178(2):315-21, 1991
                                                                  10. Rehn SM et al: Non-Hodgkin lymphoma: predicting prognostic grade with MR imaging. Radiology. 176(1):249-53, 1990
                                                                  11. Blank N et al: The mediastinum in Hodgkin's and non-Hodgkin's lymphomas. J Thorac Imaging. 2(1):66-71, 1987
                                                                  12. Bragg DG et al: New concepts in the non-Hodgkin lymphomas: radiologic implications. Radiology. 159(2):291-304, 1986
                                                                  13. Khoury MB et al: Role of chest CT in non-Hodgkin lymphoma. Radiology. 158(3):659-62, 1986
                                                                  14. Press GA et al: Thoracic wall involvement by Hodgkin disease and non-Hodgkin lymphoma: CT evaluation. Radiology. 157(1):195-8, 1985
                                                                  15. Filly R et al: Radiographic distribution of intrathoracic disease in previously untreated patients with Hodgkin's disease and non-Hodgkin's lymphoma. Radiology. 120(2):277-81, 1976