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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Germ cell neoplasm (GCN)
Definitions
Primary GCN containing tissues derived from at least 2 germinal layers
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Park JW et al: Pictorial review of mediastinal masses with an emphasis on magnetic resonance imaging. Korean J Radiol. 22(1):139-54, 2021
Prosch H et al: The role of radiological imaging for masses in the prevascular mediastinum in clinical practice. J Thorac Dis. 12(12):7591-7, 2020
Al-Khalifa M et al: A giant primary mediastinal teratocarcinoma in a male adult. Case Rep Surg. 2019:7123241, 2019
Escalon JG et al: Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation. Clin Imaging. 39(4):689-91, 2015
Patel IJ et al: AIRP best cases in radiologic-pathologic correlation: mediastinal mature cystic teratoma. Radiographics. 33(3):797-801, 2013
Takahashi K et al: Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging. 32(6):1325-39, 2010
Athanasiou A et al: Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. Eur J Radiol. 69(2):230-5, 2009
Singhal M et al: Primary mediastinal giant teratocarcinoma. Indian J Cancer. 45(2):73-4, 2008
Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
Strollo DC et al: Primary mediastinal malignant germ cell neoplasms: imaging features. Chest Surg Clin N Am. 12(4):645-58, 2002
Choi SJ et al: Mediastinal teratoma: CT differentiation of ruptured and unruptured tumors. AJR Am J Roentgenol. 171(3):591-4, 1998
Afifi HY et al: Mediastinal growing teratoma syndrome. Ann Thorac Surg. 64(2):359-62, 1997
Moeller KH et al: Mediastinal mature teratoma: imaging features. AJR Am J Roentgenol. 169(4):985-90, 1997
Moran CA et al: Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer. 80(4):681-90, 1997
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Germ cell neoplasm (GCN)
Definitions
Primary GCN containing tissues derived from at least 2 germinal layers
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Park JW et al: Pictorial review of mediastinal masses with an emphasis on magnetic resonance imaging. Korean J Radiol. 22(1):139-54, 2021
Prosch H et al: The role of radiological imaging for masses in the prevascular mediastinum in clinical practice. J Thorac Dis. 12(12):7591-7, 2020
Al-Khalifa M et al: A giant primary mediastinal teratocarcinoma in a male adult. Case Rep Surg. 2019:7123241, 2019
Escalon JG et al: Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation. Clin Imaging. 39(4):689-91, 2015
Patel IJ et al: AIRP best cases in radiologic-pathologic correlation: mediastinal mature cystic teratoma. Radiographics. 33(3):797-801, 2013
Takahashi K et al: Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging. 32(6):1325-39, 2010
Athanasiou A et al: Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. Eur J Radiol. 69(2):230-5, 2009
Singhal M et al: Primary mediastinal giant teratocarcinoma. Indian J Cancer. 45(2):73-4, 2008
Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
Strollo DC et al: Primary mediastinal malignant germ cell neoplasms: imaging features. Chest Surg Clin N Am. 12(4):645-58, 2002
Choi SJ et al: Mediastinal teratoma: CT differentiation of ruptured and unruptured tumors. AJR Am J Roentgenol. 171(3):591-4, 1998
Afifi HY et al: Mediastinal growing teratoma syndrome. Ann Thorac Surg. 64(2):359-62, 1997
Moeller KH et al: Mediastinal mature teratoma: imaging features. AJR Am J Roentgenol. 169(4):985-90, 1997
Moran CA et al: Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer. 80(4):681-90, 1997
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