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Mediastinal Teratoma
John P. Lichtenberger, III, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Germ cell neoplasm (GCN)
              • Definitions

                • Primary germ cell neoplasm containing tissues derived from at least 2 germinal layers

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Ultrasonographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Escalon JG et al: Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation. Clin Imaging. ePub, 2015
                                              2. Patel IJ et al: AIRP best cases in radiologic-pathologic correlation: mediastinal mature cystic teratoma. Radiographics. 33(3):797-801, 2013
                                              3. Takahashi K et al: Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging. 32(6):1325-39, 2010
                                              4. Athanasiou A et al: Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. Eur J Radiol. 69(2):230-5, 2009
                                              5. Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
                                              6. Strollo DC et al: Primary mediastinal malignant germ cell neoplasms: imaging features. Chest Surg Clin N Am. 12(4):645-58, 2002
                                              7. Afifi HY et al: Mediastinal growing teratoma syndrome. Ann Thorac Surg. 64(2):359-62, 1997
                                              8. Moeller KH et al: Mediastinal mature teratoma: imaging features. AJR Am J Roentgenol. 169(4):985-90, 1997
                                              9. Moran CA et al: Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer. 80(4):681-90, 1997
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Synonyms

                                                            • Germ cell neoplasm (GCN)
                                                          • Definitions

                                                            • Primary germ cell neoplasm containing tissues derived from at least 2 germinal layers

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Ultrasonographic Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Escalon JG et al: Ruptured anterior mediastinal teratoma with radiologic, pathologic, and bronchoscopic correlation. Clin Imaging. ePub, 2015
                                                                                          2. Patel IJ et al: AIRP best cases in radiologic-pathologic correlation: mediastinal mature cystic teratoma. Radiographics. 33(3):797-801, 2013
                                                                                          3. Takahashi K et al: Computed tomography and magnetic resonance imaging of mediastinal tumors. J Magn Reson Imaging. 32(6):1325-39, 2010
                                                                                          4. Athanasiou A et al: Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. Eur J Radiol. 69(2):230-5, 2009
                                                                                          5. Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
                                                                                          6. Strollo DC et al: Primary mediastinal malignant germ cell neoplasms: imaging features. Chest Surg Clin N Am. 12(4):645-58, 2002
                                                                                          7. Afifi HY et al: Mediastinal growing teratoma syndrome. Ann Thorac Surg. 64(2):359-62, 1997
                                                                                          8. Moeller KH et al: Mediastinal mature teratoma: imaging features. AJR Am J Roentgenol. 169(4):985-90, 1997
                                                                                          9. Moran CA et al: Primary germ cell tumors of the mediastinum: I. Analysis of 322 cases with special emphasis on teratomatous lesions and a proposal for histopathologic classification and clinical staging. Cancer. 80(4):681-90, 1997