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Genitourinary
Diagnosis
Kidney and Renal Pelvis
Malignant Neoplasms
Medullary Carcinoma
Medullary Carcinoma
Kevin Kalisz, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
7th sickle cell nephropathy
Definitions
Rare, aggressive tumor arising from renal papilla or calyceal epithelium of renal medulla
Associated Syndromes
Sickle cell trait (not sickle cell disease)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Sweet DE et al: Infiltrative renal malignancies: imaging features, prognostic implications, and mimics. Radiographics. 41(2):487-508, 2021
Alvarez O et al: Renal medullary carcinoma and sickle cell trait: a systematic review. Pediatr Blood Cancer. 62(10):1694-9, 2015
Shetty A et al: Renal medullary carcinoma: a case report and brief review of the literature. Ochsner J. 14(2):270-5, 2014
Alappan N et al: Renal medullary cancer in a patient with sickle cell trait. Case Rep Oncol Med. 2013:129813, 2013
Blitman NM et al: Renal medullary carcinoma: CT and MRI features. AJR Am J Roentgenol. 185(1):268-72, 2005
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
7th sickle cell nephropathy
Definitions
Rare, aggressive tumor arising from renal papilla or calyceal epithelium of renal medulla
Associated Syndromes
Sickle cell trait (not sickle cell disease)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Sweet DE et al: Infiltrative renal malignancies: imaging features, prognostic implications, and mimics. Radiographics. 41(2):487-508, 2021
Alvarez O et al: Renal medullary carcinoma and sickle cell trait: a systematic review. Pediatr Blood Cancer. 62(10):1694-9, 2015
Shetty A et al: Renal medullary carcinoma: a case report and brief review of the literature. Ochsner J. 14(2):270-5, 2014
Alappan N et al: Renal medullary cancer in a patient with sickle cell trait. Case Rep Oncol Med. 2013:129813, 2013
Blitman NM et al: Renal medullary carcinoma: CT and MRI features. AJR Am J Roentgenol. 185(1):268-72, 2005
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