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Obstetrics
Diagnosis
Brain
Posterior Fossa Malformations
Mega Cisterna Magna
Mega Cisterna Magna
Karen Y. Oh, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Mega cisterna magna (MCM)

            • Definitions

              • Cisterna magna measuring > 10 mm

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              DIAGNOSTIC CHECKLIST

                              • Image Interpretation Pearls

                                Selected References

                                1. D'Antonio F et al: Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal ultrasound: nomenclature, diagnostic accuracy and associated anomalies. Ultrasound Obstet Gynecol. ePub, 2015
                                2. Ghali R et al: Perinatal and short-term neonatal outcomes of posterior fossa anomalies. Fetal Diagn Ther. 35(2):108-17, 2014
                                3. Gandolfi Colleoni G et al: Prenatal diagnosis and outcome of fetal posterior fossa fluid collections. Ultrasound Obstet Gynecol. 39(6):625-31, 2012
                                4. Patek KJ et al: Posterior fossa anomalies diagnosed with fetal MRI: associated anomalies and neurodevelopmental outcomes. Prenat Diagn. 32(1):75-82, 2012
                                5. Bolduc ME et al: Neurodevelopmental outcomes in children with cerebellar malformations: a systematic review. Dev Med Child Neurol. 51(4):256-67, 2009
                                6. Tao G et al: Sex-related differences in the anteroposterior diameter of the foetal cisterna magna. Clin Radiol. 63(9):1015-8, 2008
                                7. Koktener A et al: The cisterna magna size in normal second-trimester fetuses. J Perinat Med. 35(3):217-9, 2007
                                8. Robinson AJ et al: The cisterna magna septa: vestigial remnants of Blake's pouch and a potential new marker for normal development of the rhombencephalon. J Ultrasound Med. 26(1):83-95, 2007
                                9. Zimmer EZ et al: Clinical significance of isolated mega cisterna magna. Arch Gynecol Obstet. 276(5):487-90, 2007
                                10. Long A et al: Outcome of fetal cerebral posterior fossa anomalies. Prenat Diagn. 26(8):707-10, 2006
                                11. Serhatlioglu S et al: Sonographic measurement of the fetal cerebellum, cisterna magna, and cavum septum pellucidum in normal fetuses in the second and third trimesters of pregnancy. J Clin Ultrasound. 31(4):194-200, 2003
                                12. Haimovici JA et al: Clinical significance of isolated enlargement of the cisterna magna (> 10 mm) on prenatal sonography. J Ultrasound Med. 16(11):731-4; quiz 735-6, 1997
                                13. Nyberg DA et al: Prenatal sonographic findings of trisomy 18: review of 47 cases. J Ultrasound Med. 12(2):103-13, 1993
                                14. Nyberg DA et al: Enlarged cisterna magna and the Dandy-Walker malformation: factors associated with chromosome abnormalities. Obstet Gynecol. 77(3):436-42, 1991
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        • Diagnostic Checklist

                                          TERMINOLOGY

                                          • Abbreviations

                                            • Mega cisterna magna (MCM)

                                          • Definitions

                                            • Cisterna magna measuring > 10 mm

                                          IMAGING

                                          • General Features

                                            • Ultrasonographic Findings

                                              • MR Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            DIAGNOSTIC CHECKLIST

                                                            • Image Interpretation Pearls

                                                              Selected References

                                                              1. D'Antonio F et al: Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal ultrasound: nomenclature, diagnostic accuracy and associated anomalies. Ultrasound Obstet Gynecol. ePub, 2015
                                                              2. Ghali R et al: Perinatal and short-term neonatal outcomes of posterior fossa anomalies. Fetal Diagn Ther. 35(2):108-17, 2014
                                                              3. Gandolfi Colleoni G et al: Prenatal diagnosis and outcome of fetal posterior fossa fluid collections. Ultrasound Obstet Gynecol. 39(6):625-31, 2012
                                                              4. Patek KJ et al: Posterior fossa anomalies diagnosed with fetal MRI: associated anomalies and neurodevelopmental outcomes. Prenat Diagn. 32(1):75-82, 2012
                                                              5. Bolduc ME et al: Neurodevelopmental outcomes in children with cerebellar malformations: a systematic review. Dev Med Child Neurol. 51(4):256-67, 2009
                                                              6. Tao G et al: Sex-related differences in the anteroposterior diameter of the foetal cisterna magna. Clin Radiol. 63(9):1015-8, 2008
                                                              7. Koktener A et al: The cisterna magna size in normal second-trimester fetuses. J Perinat Med. 35(3):217-9, 2007
                                                              8. Robinson AJ et al: The cisterna magna septa: vestigial remnants of Blake's pouch and a potential new marker for normal development of the rhombencephalon. J Ultrasound Med. 26(1):83-95, 2007
                                                              9. Zimmer EZ et al: Clinical significance of isolated mega cisterna magna. Arch Gynecol Obstet. 276(5):487-90, 2007
                                                              10. Long A et al: Outcome of fetal cerebral posterior fossa anomalies. Prenat Diagn. 26(8):707-10, 2006
                                                              11. Serhatlioglu S et al: Sonographic measurement of the fetal cerebellum, cisterna magna, and cavum septum pellucidum in normal fetuses in the second and third trimesters of pregnancy. J Clin Ultrasound. 31(4):194-200, 2003
                                                              12. Haimovici JA et al: Clinical significance of isolated enlargement of the cisterna magna (> 10 mm) on prenatal sonography. J Ultrasound Med. 16(11):731-4; quiz 735-6, 1997
                                                              13. Nyberg DA et al: Prenatal sonographic findings of trisomy 18: review of 47 cases. J Ultrasound Med. 12(2):103-13, 1993
                                                              14. Nyberg DA et al: Enlarged cisterna magna and the Dandy-Walker malformation: factors associated with chromosome abnormalities. Obstet Gynecol. 77(3):436-42, 1991
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