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Melanoma
Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Malignant melanoma
          • Definitions

            • Malignant tumor of melanocytes usually appearing as skin lesion that is asymmetric, with irregular border, uneven color, and diameter > 6 mm

          IMAGING

          • General Features

            • Imaging Recommendations

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Image-Guided Biopsy

                      • Nuclear Medicine Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. Gray MR et al: Metastatic melanoma: lactate dehydrogenase levels and CT imaging findings of tumor devascularization allow accurate prediction of survival in patients treated with bevacizumab. Radiology. 270(2):425-34, 2014
                                              2. Rahim S et al: Correlation of PUV and SUV in the extremities while using PEM as a high-resolution positron emission scanner. Skeletal Radiol. 43(4):453-8, 2014
                                              3. Catalano O et al: Locoregional spread of cutaneous melanoma: sonography findings. AJR Am J Roentgenol. 194(3):735-45, 2010
                                              4. Melanoma of the skin staging form. In AJCC Cancer Staging Manual. 7th ed. New York: Springer. 341-4, 2010
                                              5. The NCCN Melanoma Clinical Practice Guidelines in Oncology (Version 1.2010). © 2010 National Comprehensive Cancer Network, Inc. Available at: http://www.nccn.org/professionals/physician_gls/ f_guidelines.asp. Accessed March 9, 2010
                                              6. Krug B et al: Role of PET in the initial staging of cutaneous malignant melanoma: systematic review. Radiology. 249(3):836-44, 2008
                                              7. De vries E et al: Malignant melanoma: Introduction. In LeBoit PE et al: World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press. 52-65; 2006
                                              8. Yoshioka H et al: Intramuscular metastasis from malignant melanoma: MR findings. Skeletal Radiol. 28(12):714-6, 1999
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Malignant melanoma
                                                      • Definitions

                                                        • Malignant tumor of melanocytes usually appearing as skin lesion that is asymmetric, with irregular border, uneven color, and diameter > 6 mm

                                                      IMAGING

                                                      • General Features

                                                        • Imaging Recommendations

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Image-Guided Biopsy

                                                                  • Nuclear Medicine Findings

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. Gray MR et al: Metastatic melanoma: lactate dehydrogenase levels and CT imaging findings of tumor devascularization allow accurate prediction of survival in patients treated with bevacizumab. Radiology. 270(2):425-34, 2014
                                                                                          2. Rahim S et al: Correlation of PUV and SUV in the extremities while using PEM as a high-resolution positron emission scanner. Skeletal Radiol. 43(4):453-8, 2014
                                                                                          3. Catalano O et al: Locoregional spread of cutaneous melanoma: sonography findings. AJR Am J Roentgenol. 194(3):735-45, 2010
                                                                                          4. Melanoma of the skin staging form. In AJCC Cancer Staging Manual. 7th ed. New York: Springer. 341-4, 2010
                                                                                          5. The NCCN Melanoma Clinical Practice Guidelines in Oncology (Version 1.2010). © 2010 National Comprehensive Cancer Network, Inc. Available at: http://www.nccn.org/professionals/physician_gls/ f_guidelines.asp. Accessed March 9, 2010
                                                                                          6. Krug B et al: Role of PET in the initial staging of cutaneous malignant melanoma: systematic review. Radiology. 249(3):836-44, 2008
                                                                                          7. De vries E et al: Malignant melanoma: Introduction. In LeBoit PE et al: World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press. 52-65; 2006
                                                                                          8. Yoshioka H et al: Intramuscular metastasis from malignant melanoma: MR findings. Skeletal Radiol. 28(12):714-6, 1999