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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Melanotic neuroectodermal tumor of infancy (MNTI)
Synonyms
- Melanotic progonoma, melanin-containing primitive neuroectodermal tumor, retinal anlage tumor
Definitions
- Rare, locally aggressive pigmented tumor of infancy
- Do not confuse with neurocutaneous melanosis
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Jakchairoongruang K et al: New insights into neurocutaneous melanosis. Pediatr Radiol. 48(12):1786-96, 2018
- Moreau A et al: Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: a French multicenter study. J Craniomaxillofac Surg. 46(2):201-6, 2018
- Yoo IH et al: Melanotic neuroectodermal tumor of infancy disseminated by a ventriculoperitoneal shunt and diagnosed from the inguinal sac. J Pediatr Hematol Oncol. 36(1):e61-4, 2014
- Naidoo J et al: Melanotic neuroectodermal tumour of infancy, a rare cause for a bump on the head. Childs Nerv Syst. 29(1):167-72, 2013
- Furtado SV et al: Calvarial malignant melanotic neuroectodermal tumour of infancy presenting with widespread intracranial metastasis. J Craniomaxillofac Surg. 40(6):e170-3, 2012
- Haque S et al: Melanotic neuroectodermal tumour of infancy: CT and MR findings. Pediatr Radiol. 42(6):699-705, 2012
- Manojlović S et al: Melanotic neuroectodermal tumour of infancy: report of two cases and review of the literature. J Craniomaxillofac Surg. 40(4):e103-7, 2012
- Saleem S et al: Melanotic neuroectodermal tumor of the calvarium. Pediatr Radiol. 40 Suppl 1:S159, 2010
- Chaudhary A et al: Melanotic neuroectodermal tumor of infancy: 2 decades of clinical experience with 18 patients. J Oral Maxillofac Surg. 67(1):47-51, 2009
- Kantar M et al: Melanotic progonoma of the skull in infancy. Childs Nerv Syst. 24(11):1371-5, 2008
- Kumari TP et al: Effectiveness of chemotherapy in melanotic neurectodermal tumor of infancy. Pediatr Hematol Oncol. 22(3):199-206, 2005
- Rickert CH et al: Melanotic progonoma of the brain: a case report and review. Childs Nerv Syst. 14(8):389-93, 1998
- Williams AO: Melanotic ameloblastoma ("progonoma") of infancy showing osteogenesis. J Pathol Bacteriol. 93(2):545-8, 1967
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Melanotic neuroectodermal tumor of infancy (MNTI)
Synonyms
- Melanotic progonoma, melanin-containing primitive neuroectodermal tumor, retinal anlage tumor
Definitions
- Rare, locally aggressive pigmented tumor of infancy
- Do not confuse with neurocutaneous melanosis
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Jakchairoongruang K et al: New insights into neurocutaneous melanosis. Pediatr Radiol. 48(12):1786-96, 2018
- Moreau A et al: Melanotic neuroectodermal tumor of infancy (MNTI) of the head and neck: a French multicenter study. J Craniomaxillofac Surg. 46(2):201-6, 2018
- Yoo IH et al: Melanotic neuroectodermal tumor of infancy disseminated by a ventriculoperitoneal shunt and diagnosed from the inguinal sac. J Pediatr Hematol Oncol. 36(1):e61-4, 2014
- Naidoo J et al: Melanotic neuroectodermal tumour of infancy, a rare cause for a bump on the head. Childs Nerv Syst. 29(1):167-72, 2013
- Furtado SV et al: Calvarial malignant melanotic neuroectodermal tumour of infancy presenting with widespread intracranial metastasis. J Craniomaxillofac Surg. 40(6):e170-3, 2012
- Haque S et al: Melanotic neuroectodermal tumour of infancy: CT and MR findings. Pediatr Radiol. 42(6):699-705, 2012
- Manojlović S et al: Melanotic neuroectodermal tumour of infancy: report of two cases and review of the literature. J Craniomaxillofac Surg. 40(4):e103-7, 2012
- Saleem S et al: Melanotic neuroectodermal tumor of the calvarium. Pediatr Radiol. 40 Suppl 1:S159, 2010
- Chaudhary A et al: Melanotic neuroectodermal tumor of infancy: 2 decades of clinical experience with 18 patients. J Oral Maxillofac Surg. 67(1):47-51, 2009
- Kantar M et al: Melanotic progonoma of the skull in infancy. Childs Nerv Syst. 24(11):1371-5, 2008
- Kumari TP et al: Effectiveness of chemotherapy in melanotic neurectodermal tumor of infancy. Pediatr Hematol Oncol. 22(3):199-206, 2005
- Rickert CH et al: Melanotic progonoma of the brain: a case report and review. Childs Nerv Syst. 14(8):389-93, 1998
- Williams AO: Melanotic ameloblastoma ("progonoma") of infancy showing osteogenesis. J Pathol Bacteriol. 93(2):545-8, 1967
