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Meningioma
Jeffrey S. Ross, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Slow-growing, benign tumor originating from dura mater

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Angiographic Findings

                    • Nonvascular Interventions

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Smith MJ et al: Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas. Nat Genet. 45(3):295-8, 2013
                                              2. Nakamura M et al: Long-term surgical outcomes of spinal meningiomas. Spine (Phila Pa 1976). 37(10):E617-23, 2012
                                              3. Wang XQ et al: Spinal meningioma in childhood: clinical features and treatment. Childs Nerv Syst. 28(1):129-36, 2012
                                              4. Liu WC et al: Radiological findings of spinal schwannomas and meningiomas: focus on discrimination of two disease entities. Eur Radiol. 19(11):2707-15, 2009
                                              5. Gerszten PC et al: Radiosurgery for benign intradural spinal tumors. Neurosurgery. 62(4):887-95; discussion 895-6, 2008
                                              6. Sandalcioglu IE et al: Spinal meningiomas: critical review of 131 surgically treated patients. Eur Spine J. 17(8):1035-41, 2008
                                              7. Cohen-Gadol AA et al: Spinal meningiomas in patients younger than 50 years of age: a 21-year experience. J Neurosurg. 98(3 Suppl):258-63, 2003
                                              8. Covert S et al: Magnetic resonance imaging of intramedullary meningioma of the spinal cord: case report and review of the literature. Can Assoc Radiol J. 54(3):177-80, 2003
                                              9. Lucey BP et al: Spinal meningioma causing diffuse leptomeningeal enhancement. Neurology. 60(2):350-1, 2003
                                              10. Doita M et al: Recurrent calcified spinal meningioma detected by plain radiograph. Spine. 26(11):E249-52, 2001
                                              11. Eastwood JD et al: Diffusion-weighted MR imaging in a patient with spinal meningioma. AJR Am J Roentgenol. 177(6):1479-81, 2001
                                              12. Louis DN et al: Meningiomas. In Kleihues P, Cavanee WK. Tumours of the Nervous System. Lyon: IARC Press. 176-84, 2000
                                              13. Naderi S: Spinal meningiomas. Surg Neurol. 54(1):95, 2000
                                              14. Klekamp J et al: Surgical results for spinal meningiomas. Surg Neurol. 52(6):552-62, 1999
                                              15. Yoshiura T et al: Cervical spinal meningioma with unusual MR contrast enhancement. AJNR Am J Neuroradiol. 19(6):1040-2, 1998
                                              16. Sato N et al: Extradural spinal meningioma: MRI. Neuroradiology. 39(6):450-2, 1997
                                              17. Borden NM: Aggressive angioblastic meningioma with multiple sites in the neural axis. AJNR Am J Neuroradiol. 16(4):793-4, 1995
                                              18. Akeson P et al: Radiological investigation of neurofibromatosis type 2. Neuroradiology. 36(2):107-10, 1994
                                              19. Souweidane MM et al: Spinal cord meningiomas. Neurosurg Clin N Am. 5(2):283-91, 1994
                                              20. Kabus D et al: Metastatic meningioma. Hemangiopericytoma or angioblastic meningioma? Am J Surg Pathol. 17(11):1144-50, 1993
                                              21. Kannuki S et al: Coexistence of intracranial and spinal meningiomas--report of two cases. Neurol Med Chir (Tokyo). 31(11):720-4, 1991
                                              22. Solero CL et al: Spinal meningiomas: review of 174 operated cases. Neurosurgery. 25(2):153-60, 1989
                                              23. Levy WJ Jr et al: Spinal cord meningioma. J Neurosurg. 57(6):804-12, 1982
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Definitions

                                                        • Slow-growing, benign tumor originating from dura mater

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Angiographic Findings

                                                                • Nonvascular Interventions

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Smith MJ et al: Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas. Nat Genet. 45(3):295-8, 2013
                                                                                          2. Nakamura M et al: Long-term surgical outcomes of spinal meningiomas. Spine (Phila Pa 1976). 37(10):E617-23, 2012
                                                                                          3. Wang XQ et al: Spinal meningioma in childhood: clinical features and treatment. Childs Nerv Syst. 28(1):129-36, 2012
                                                                                          4. Liu WC et al: Radiological findings of spinal schwannomas and meningiomas: focus on discrimination of two disease entities. Eur Radiol. 19(11):2707-15, 2009
                                                                                          5. Gerszten PC et al: Radiosurgery for benign intradural spinal tumors. Neurosurgery. 62(4):887-95; discussion 895-6, 2008
                                                                                          6. Sandalcioglu IE et al: Spinal meningiomas: critical review of 131 surgically treated patients. Eur Spine J. 17(8):1035-41, 2008
                                                                                          7. Cohen-Gadol AA et al: Spinal meningiomas in patients younger than 50 years of age: a 21-year experience. J Neurosurg. 98(3 Suppl):258-63, 2003
                                                                                          8. Covert S et al: Magnetic resonance imaging of intramedullary meningioma of the spinal cord: case report and review of the literature. Can Assoc Radiol J. 54(3):177-80, 2003
                                                                                          9. Lucey BP et al: Spinal meningioma causing diffuse leptomeningeal enhancement. Neurology. 60(2):350-1, 2003
                                                                                          10. Doita M et al: Recurrent calcified spinal meningioma detected by plain radiograph. Spine. 26(11):E249-52, 2001
                                                                                          11. Eastwood JD et al: Diffusion-weighted MR imaging in a patient with spinal meningioma. AJR Am J Roentgenol. 177(6):1479-81, 2001
                                                                                          12. Louis DN et al: Meningiomas. In Kleihues P, Cavanee WK. Tumours of the Nervous System. Lyon: IARC Press. 176-84, 2000
                                                                                          13. Naderi S: Spinal meningiomas. Surg Neurol. 54(1):95, 2000
                                                                                          14. Klekamp J et al: Surgical results for spinal meningiomas. Surg Neurol. 52(6):552-62, 1999
                                                                                          15. Yoshiura T et al: Cervical spinal meningioma with unusual MR contrast enhancement. AJNR Am J Neuroradiol. 19(6):1040-2, 1998
                                                                                          16. Sato N et al: Extradural spinal meningioma: MRI. Neuroradiology. 39(6):450-2, 1997
                                                                                          17. Borden NM: Aggressive angioblastic meningioma with multiple sites in the neural axis. AJNR Am J Neuroradiol. 16(4):793-4, 1995
                                                                                          18. Akeson P et al: Radiological investigation of neurofibromatosis type 2. Neuroradiology. 36(2):107-10, 1994
                                                                                          19. Souweidane MM et al: Spinal cord meningiomas. Neurosurg Clin N Am. 5(2):283-91, 1994
                                                                                          20. Kabus D et al: Metastatic meningioma. Hemangiopericytoma or angioblastic meningioma? Am J Surg Pathol. 17(11):1144-50, 1993
                                                                                          21. Kannuki S et al: Coexistence of intracranial and spinal meningiomas--report of two cases. Neurol Med Chir (Tokyo). 31(11):720-4, 1991
                                                                                          22. Solero CL et al: Spinal meningiomas: review of 174 operated cases. Neurosurgery. 25(2):153-60, 1989
                                                                                          23. Levy WJ Jr et al: Spinal cord meningioma. J Neurosurg. 57(6):804-12, 1982