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Merkel Cell Tumor
Christine O. Menias, MD; Oguz Akin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Trabecular carcinoma, endocrine carcinoma, primary cutaneous neuroendocrine carcinoma
          • Definitions

            • Rare neuroendocrine carcinoma with aggressive behavior arising from Merkel cells in basal layer of epidermis

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • Gross Pathologic & Surgical Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                Selected References

                                1. Jońska-Gmyrek J et al: [Merkel cell carcinoma of the vulva - case report and the literature review.] Ginekol Pol. 84(5):385-9, 2013
                                2. Iavazzo C et al: Vulvar merkel carcinoma: a case report. Case Rep Med. 2011:546972, 2011
                                3. Albores-Saavedra J et al: Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study. J Cutan Pathol. 37(1):20-7, 2010
                                4. Sheikh ZA et al: Neuroendocrine tumor of vulva: a case report and review of literature. J Cancer Res Ther. 6(3):365-6, 2010
                                5. Mohit M et al: Merkel cell carcinoma of the vulva. Saudi Med J. 30(5):717-8, 2009
                                6. Zucchi S: Merkel cell carcinoma: case report and literature review, from a remote region of France. Rural Remote Health. 9(1):1072, 2009
                                7. Khoury-Collado F et al: Merkel cell carcinoma of the Bartholin's gland. Gynecol Oncol. 97(3):928-31, 2005
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Pathology

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Synonyms

                                          • Trabecular carcinoma, endocrine carcinoma, primary cutaneous neuroendocrine carcinoma
                                        • Definitions

                                          • Rare neuroendocrine carcinoma with aggressive behavior arising from Merkel cells in basal layer of epidermis

                                        IMAGING

                                        • General Features

                                          • CT Findings

                                            • MR Findings

                                              • Imaging Recommendations

                                                DIFFERENTIAL DIAGNOSIS

                                                  PATHOLOGY

                                                  • Gross Pathologic & Surgical Features

                                                    • Microscopic Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            • Treatment

                                                              Selected References

                                                              1. Jońska-Gmyrek J et al: [Merkel cell carcinoma of the vulva - case report and the literature review.] Ginekol Pol. 84(5):385-9, 2013
                                                              2. Iavazzo C et al: Vulvar merkel carcinoma: a case report. Case Rep Med. 2011:546972, 2011
                                                              3. Albores-Saavedra J et al: Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study. J Cutan Pathol. 37(1):20-7, 2010
                                                              4. Sheikh ZA et al: Neuroendocrine tumor of vulva: a case report and review of literature. J Cancer Res Ther. 6(3):365-6, 2010
                                                              5. Mohit M et al: Merkel cell carcinoma of the vulva. Saudi Med J. 30(5):717-8, 2009
                                                              6. Zucchi S: Merkel cell carcinoma: case report and literature review, from a remote region of France. Rural Remote Health. 9(1):1072, 2009
                                                              7. Khoury-Collado F et al: Merkel cell carcinoma of the Bartholin's gland. Gynecol Oncol. 97(3):928-31, 2005