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Mesoblastic Nephroma
Paula J. Woodward, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Congenital mesoblastic nephroma
              • Fetal renal hamartoma
              • Leiomyomatous hamartoma
              • Mesenchymal hamartoma
              • Bolande tumor
            • Definitions

              • Benign mesenchymal renal tumor composed predominately of spindle cells

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Do AY et al: Prenatal diagnosis of congenital mesoblastic nephroma. Obstet Gynecol Sci. 58(5):405-8, 2015
                                        2. Takahashi H et al: Congenital mesoblastic nephroma: Its diverse clinical features - A literature review with a case report. J Obstet Gynaecol. 1-5, 2015
                                        3. Wang ZP et al: Congenital mesoblastic nephroma: clinical analysis of eight cases and a review of the literature. Oncol Lett. 8(5):2007-2011, 2014
                                        4. Esmer AC et al: Prenatal sonographic diagnosis of multicystic congenital mesoblastic nephroma. J Clin Ultrasound. 41 Suppl 1:59-61, 2013
                                        5. Ko SM et al: Cellular mesoblastic nephroma with liver metastasis in a neonate: prenatal and postnatal diffusion-weighted MR imaging. Korean J Radiol. 14(2):361-5, 2013
                                        6. Sheth MM et al: AIRP best cases in radiologic-pathologic correlation: congenital mesoblastic nephroma. Radiographics. 32(1):99-103, 2012
                                        7. De Paepe ME et al: Intrauterine demise due to congenital mesoblastic nephroma in a fetus conceived by assisted reproductive technology. Fertil Steril. Epub ahead of print, 2010
                                        8. Kim CH et al: A case of fetal congenital mesoblastic nephroma with oligohydramnios. J Korean Med Sci. 22(2):357-61, 2007
                                        9. Yamamoto N et al: Mesoblastic nephroma: a case report of prenatal detection by MR imaging. Magn Reson Med Sci. 5(1):47-50, 2006
                                        10. Canning DA: Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. J Urol. 173(3):983, 2005
                                        11. Khashu M et al: Congenital mesoblastic nephroma presenting with neonatal hypertension. J Perinatol. 25(6):433-5, 2005
                                        12. Leclair MD et al: The outcome of prenatally diagnosed renal tumors. J Urol. 173(1):186-9, 2005
                                        13. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                        14. Chen WY et al: Prenatal diagnosis of congenital mesoblastic nephroma in mid-second trimester by sonography and magnetic resonance imaging. Prenat Diagn. 23(11):927-31, 2003
                                        15. Kelner M et al: The vascular "ring" sign in mesoblastic nephroma: report of two cases. Pediatr Radiol. 33(2):123-8, 2003
                                        16. Won HS et al: Prenatal detection of mesoblastic nephroma by sonography and magnetic resonance imaging. Ultrasound Obstet Gynecol. 19(2):197-9, 2002
                                        17. Irsutti M et al: Mesoblastic nephroma: prenatal ultrasonographic and MRI features. Pediatr Radiol. 30(3):147-50, 2000
                                        18. Liu YC et al: The presence of hydrops fetalis in a fetus with congenital mesoblastic nephroma. Prenat Diagn. 16(4):363-5, 1996
                                        19. Fung TY et al: Polyhydramnios and hypercalcemia associated with congenital mesoblastic nephroma: case report and a new appraisal. Obstet Gynecol. 85(5 Pt 2):815-7, 1995
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Congenital mesoblastic nephroma
                                                    • Fetal renal hamartoma
                                                    • Leiomyomatous hamartoma
                                                    • Mesenchymal hamartoma
                                                    • Bolande tumor
                                                  • Definitions

                                                    • Benign mesenchymal renal tumor composed predominately of spindle cells

                                                  IMAGING

                                                  • General Features

                                                    • Ultrasonographic Findings

                                                      • MR Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Do AY et al: Prenatal diagnosis of congenital mesoblastic nephroma. Obstet Gynecol Sci. 58(5):405-8, 2015
                                                                              2. Takahashi H et al: Congenital mesoblastic nephroma: Its diverse clinical features - A literature review with a case report. J Obstet Gynaecol. 1-5, 2015
                                                                              3. Wang ZP et al: Congenital mesoblastic nephroma: clinical analysis of eight cases and a review of the literature. Oncol Lett. 8(5):2007-2011, 2014
                                                                              4. Esmer AC et al: Prenatal sonographic diagnosis of multicystic congenital mesoblastic nephroma. J Clin Ultrasound. 41 Suppl 1:59-61, 2013
                                                                              5. Ko SM et al: Cellular mesoblastic nephroma with liver metastasis in a neonate: prenatal and postnatal diffusion-weighted MR imaging. Korean J Radiol. 14(2):361-5, 2013
                                                                              6. Sheth MM et al: AIRP best cases in radiologic-pathologic correlation: congenital mesoblastic nephroma. Radiographics. 32(1):99-103, 2012
                                                                              7. De Paepe ME et al: Intrauterine demise due to congenital mesoblastic nephroma in a fetus conceived by assisted reproductive technology. Fertil Steril. Epub ahead of print, 2010
                                                                              8. Kim CH et al: A case of fetal congenital mesoblastic nephroma with oligohydramnios. J Korean Med Sci. 22(2):357-61, 2007
                                                                              9. Yamamoto N et al: Mesoblastic nephroma: a case report of prenatal detection by MR imaging. Magn Reson Med Sci. 5(1):47-50, 2006
                                                                              10. Canning DA: Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. J Urol. 173(3):983, 2005
                                                                              11. Khashu M et al: Congenital mesoblastic nephroma presenting with neonatal hypertension. J Perinatol. 25(6):433-5, 2005
                                                                              12. Leclair MD et al: The outcome of prenatally diagnosed renal tumors. J Urol. 173(1):186-9, 2005
                                                                              13. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                                                              14. Chen WY et al: Prenatal diagnosis of congenital mesoblastic nephroma in mid-second trimester by sonography and magnetic resonance imaging. Prenat Diagn. 23(11):927-31, 2003
                                                                              15. Kelner M et al: The vascular "ring" sign in mesoblastic nephroma: report of two cases. Pediatr Radiol. 33(2):123-8, 2003
                                                                              16. Won HS et al: Prenatal detection of mesoblastic nephroma by sonography and magnetic resonance imaging. Ultrasound Obstet Gynecol. 19(2):197-9, 2002
                                                                              17. Irsutti M et al: Mesoblastic nephroma: prenatal ultrasonographic and MRI features. Pediatr Radiol. 30(3):147-50, 2000
                                                                              18. Liu YC et al: The presence of hydrops fetalis in a fetus with congenital mesoblastic nephroma. Prenat Diagn. 16(4):363-5, 1996
                                                                              19. Fung TY et al: Polyhydramnios and hypercalcemia associated with congenital mesoblastic nephroma: case report and a new appraisal. Obstet Gynecol. 85(5 Pt 2):815-7, 1995