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Mesoblastic Nephroma
Paula J. Woodward, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Congenital mesoblastic nephroma
              • Fetal renal hamartoma
              • Leiomyomatous hamartoma
              • Bolande tumor
            • Definitions

              • Benign mesenchymal renal tumor composed predominately of spindle cells

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Pachl M et al: Congenital mesoblastic nephroma: a single-centre series. Ann R Coll Surg Engl. 102(1):67-70, 2020
                                        2. Schild RL et al: Diagnosis of a fetal mesoblastic nephroma by 3D-ultrasound. Ultrasound Obstet Gynecol. 15(6):533-6, 2000
                                        3. Rampersad F et al: The clinical presentation, imaging features and differential diagnoses of congenital Wilms tumour. BMJ Case Rep. 12(5), 2019
                                        4. Mata RP et al: Prenatal diagnosis of congenital mesoblastic nephroma: a case with poor prognosis. BMJ Case Rep. 12(8), 2019
                                        5. Daniel J et al: Management of mixed type congenital mesoblastic nephroma: case series and review of the literature. J Neonatal Perinatal Med. 10(1):113-8, 2017
                                        6. Berger M et al: Current management of fetal and neonatal renal tumors. Curr Pediatr Rev. 11(3):188-94, 2015
                                        7. Do AY et al: Prenatal diagnosis of congenital mesoblastic nephroma. Obstet Gynecol Sci. 58(5):405-8, 2015
                                        8. Takahashi H et al: Congenital mesoblastic nephroma: Its diverse clinical features - a literature review with a case report. J Obstet Gynaecol. 1-5, 2015
                                        9. Wang ZP et al: Congenital mesoblastic nephroma: clinical analysis of eight cases and a review of the literature. Oncol Lett. 8(5):2007-11, 2014
                                        10. Esmer AC et al: Prenatal sonographic diagnosis of multicystic congenital mesoblastic nephroma. J Clin Ultrasound. 41 Suppl 1:59-61, 2013
                                        11. Ko SM et al: Cellular mesoblastic nephroma with liver metastasis in a neonate: prenatal and postnatal diffusion-weighted MR imaging. Korean J Radiol. 14(2):361-5, 2013
                                        12. Sheth MM et al: AIRP best cases in radiologic-pathologic correlation: congenital mesoblastic nephroma. Radiographics. 32(1):99-103, 2012
                                        13. Canning DA: Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. J Urol. 173(3):983, 2005
                                        14. Khashu M et al: Congenital mesoblastic nephroma presenting with neonatal hypertension. J Perinatol. 25(6):433-5, 2005
                                        15. Leclair MD et al: The outcome of prenatally diagnosed renal tumors. J Urol. 173(1):186-9, 2005
                                        16. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                        17. Chen WY et al: Prenatal diagnosis of congenital mesoblastic nephroma in mid-second trimester by sonography and magnetic resonance imaging. Prenat Diagn. 23(11):927-31, 2003
                                        18. Kelner M et al: The vascular "ring" sign in mesoblastic nephroma: report of two cases. Pediatr Radiol. 33(2):123-8, 2003
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Congenital mesoblastic nephroma
                                                    • Fetal renal hamartoma
                                                    • Leiomyomatous hamartoma
                                                    • Bolande tumor
                                                  • Definitions

                                                    • Benign mesenchymal renal tumor composed predominately of spindle cells

                                                  IMAGING

                                                  • General Features

                                                    • Ultrasonographic Findings

                                                      • MR Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Pachl M et al: Congenital mesoblastic nephroma: a single-centre series. Ann R Coll Surg Engl. 102(1):67-70, 2020
                                                                              2. Schild RL et al: Diagnosis of a fetal mesoblastic nephroma by 3D-ultrasound. Ultrasound Obstet Gynecol. 15(6):533-6, 2000
                                                                              3. Rampersad F et al: The clinical presentation, imaging features and differential diagnoses of congenital Wilms tumour. BMJ Case Rep. 12(5), 2019
                                                                              4. Mata RP et al: Prenatal diagnosis of congenital mesoblastic nephroma: a case with poor prognosis. BMJ Case Rep. 12(8), 2019
                                                                              5. Daniel J et al: Management of mixed type congenital mesoblastic nephroma: case series and review of the literature. J Neonatal Perinatal Med. 10(1):113-8, 2017
                                                                              6. Berger M et al: Current management of fetal and neonatal renal tumors. Curr Pediatr Rev. 11(3):188-94, 2015
                                                                              7. Do AY et al: Prenatal diagnosis of congenital mesoblastic nephroma. Obstet Gynecol Sci. 58(5):405-8, 2015
                                                                              8. Takahashi H et al: Congenital mesoblastic nephroma: Its diverse clinical features - a literature review with a case report. J Obstet Gynaecol. 1-5, 2015
                                                                              9. Wang ZP et al: Congenital mesoblastic nephroma: clinical analysis of eight cases and a review of the literature. Oncol Lett. 8(5):2007-11, 2014
                                                                              10. Esmer AC et al: Prenatal sonographic diagnosis of multicystic congenital mesoblastic nephroma. J Clin Ultrasound. 41 Suppl 1:59-61, 2013
                                                                              11. Ko SM et al: Cellular mesoblastic nephroma with liver metastasis in a neonate: prenatal and postnatal diffusion-weighted MR imaging. Korean J Radiol. 14(2):361-5, 2013
                                                                              12. Sheth MM et al: AIRP best cases in radiologic-pathologic correlation: congenital mesoblastic nephroma. Radiographics. 32(1):99-103, 2012
                                                                              13. Canning DA: Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. J Urol. 173(3):983, 2005
                                                                              14. Khashu M et al: Congenital mesoblastic nephroma presenting with neonatal hypertension. J Perinatol. 25(6):433-5, 2005
                                                                              15. Leclair MD et al: The outcome of prenatally diagnosed renal tumors. J Urol. 173(1):186-9, 2005
                                                                              16. Woodward PJ et al: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics. 25(1):215-42, 2005
                                                                              17. Chen WY et al: Prenatal diagnosis of congenital mesoblastic nephroma in mid-second trimester by sonography and magnetic resonance imaging. Prenat Diagn. 23(11):927-31, 2003
                                                                              18. Kelner M et al: The vascular "ring" sign in mesoblastic nephroma: report of two cases. Pediatr Radiol. 33(2):123-8, 2003