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Metastatic Melanoma
Siva P. Raman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Spectrum of metastatic lesions originating from known or occult malignant melanoma

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Fluoroscopic Findings

                        • Nuclear Medicine Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Baker JJ et al: Routine restaging PET/CT and detection of initial recurrence in sentinel lymph node positive stage III melanoma. Am J Surg. 207(4):549-54, 2014
                                                2. Choi WS et al: CT findings of gallbladder metastases: emphasis on differences according to primary tumors. Korean J Radiol. 15(3):334-45, 2014
                                                3. Trout AT et al: Melanoma metastases in the abdomen and pelvis: Frequency and patterns of spread. World J Radiol. 5(2):25-32, 2013
                                                4. Sofue K et al: MR imaging of hepatic metastasis in patients with malignant melanoma: evaluation of suspected lesions screened at contrast-enhanced CT. Eur J Radiol. 81(4):714-8, 2012
                                                5. Barretta ML et al: Gallbladder metastasis: spectrum of imaging findings. Abdom Imaging. 36(6):729-34, 2011
                                                6. Patnana M et al: Multimethod imaging, staging, and spectrum of manifestations of metastatic melanoma. Clin Radiol. 66(3):224-36, 2011
                                                7. Intenzo CM et al: Lymphoscintigraphy in cutaneous melanoma: an updated total body atlas of sentinel node mapping. Radiographics. 29(4):1125-35, 2009
                                                8. Martel JP et al: Melanoma of the gallbladder. Radiographics. 29(1):291-6, 2009
                                                9. Pleiss C et al: Role of FDG-PET in the assessment of survival prognosis in melanoma. Cancer Biother Radiopharm. 22(6):740-7, 2007
                                                10. Strobel K et al: High-risk melanoma: accuracy of FDG PET/CT with added CT morphologic information for detection of metastases. Radiology. 244(2):566-74, 2007
                                                11. King DM: Imaging of metastatic melanoma. Cancer Imaging. 6:204-8, 2006
                                                12. Vucetić B et al: The role of preoperative lymphoscintigraphy in surgery planning for sentinel lymph node biopsy in malignant melanoma. Wien Klin Wochenschr. 118(9-10):286-93, 2006
                                                13. Petro A et al: Current melanoma staging. Clin Dermatol. 22(3):223-7, 2004
                                                14. Hubalewska A et al: Use of Tc99m-nanocolloid for sentinel nodes identification in cervical cancer. Nucl Med Rev Cent East Eur. 6(2):127-30, 2003
                                                15. Sumner WE 3rd et al: Implications of lymphatic drainage to unusual sentinel lymph node sites in patients with primary cutaneous melanoma. Cancer. 95(2):354-60, 2002
                                                16. Blake SP et al: Liver metastases from melanoma: detection with multiphasic contrast-enhanced CT. Radiology. 213(1):92-6, 1999
                                                17. Kamel IR et al: Imaging of abdominal manifestations of melanoma. Crit Rev Diagn Imaging. 39(6):447-86, 1998
                                                18. Fishman EK et al: CT of malignant melanoma in the chest, abdomen, and musculoskeletal system. Radiographics. 10(4):603-20, 1990
                                                19. Stutte H et al: Ultrasonographic diagnosis of melanoma metastases in liver, gallbladder, and spleen. J Ultrasound Med. 8(10):541-7, 1989
                                                20. Daunt N et al: Metastatic melanoma in the biliary tree. Br J Radiol. 55(659):873-4, 1982
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Spectrum of metastatic lesions originating from known or occult malignant melanoma

                                                        IMAGING

                                                        • General Features

                                                          • Imaging Recommendations

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Ultrasonographic Findings

                                                                    • Fluoroscopic Findings

                                                                      • Nuclear Medicine Findings

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Staging, Grading, & Classification

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Baker JJ et al: Routine restaging PET/CT and detection of initial recurrence in sentinel lymph node positive stage III melanoma. Am J Surg. 207(4):549-54, 2014
                                                                                              2. Choi WS et al: CT findings of gallbladder metastases: emphasis on differences according to primary tumors. Korean J Radiol. 15(3):334-45, 2014
                                                                                              3. Trout AT et al: Melanoma metastases in the abdomen and pelvis: Frequency and patterns of spread. World J Radiol. 5(2):25-32, 2013
                                                                                              4. Sofue K et al: MR imaging of hepatic metastasis in patients with malignant melanoma: evaluation of suspected lesions screened at contrast-enhanced CT. Eur J Radiol. 81(4):714-8, 2012
                                                                                              5. Barretta ML et al: Gallbladder metastasis: spectrum of imaging findings. Abdom Imaging. 36(6):729-34, 2011
                                                                                              6. Patnana M et al: Multimethod imaging, staging, and spectrum of manifestations of metastatic melanoma. Clin Radiol. 66(3):224-36, 2011
                                                                                              7. Intenzo CM et al: Lymphoscintigraphy in cutaneous melanoma: an updated total body atlas of sentinel node mapping. Radiographics. 29(4):1125-35, 2009
                                                                                              8. Martel JP et al: Melanoma of the gallbladder. Radiographics. 29(1):291-6, 2009
                                                                                              9. Pleiss C et al: Role of FDG-PET in the assessment of survival prognosis in melanoma. Cancer Biother Radiopharm. 22(6):740-7, 2007
                                                                                              10. Strobel K et al: High-risk melanoma: accuracy of FDG PET/CT with added CT morphologic information for detection of metastases. Radiology. 244(2):566-74, 2007
                                                                                              11. King DM: Imaging of metastatic melanoma. Cancer Imaging. 6:204-8, 2006
                                                                                              12. Vucetić B et al: The role of preoperative lymphoscintigraphy in surgery planning for sentinel lymph node biopsy in malignant melanoma. Wien Klin Wochenschr. 118(9-10):286-93, 2006
                                                                                              13. Petro A et al: Current melanoma staging. Clin Dermatol. 22(3):223-7, 2004
                                                                                              14. Hubalewska A et al: Use of Tc99m-nanocolloid for sentinel nodes identification in cervical cancer. Nucl Med Rev Cent East Eur. 6(2):127-30, 2003
                                                                                              15. Sumner WE 3rd et al: Implications of lymphatic drainage to unusual sentinel lymph node sites in patients with primary cutaneous melanoma. Cancer. 95(2):354-60, 2002
                                                                                              16. Blake SP et al: Liver metastases from melanoma: detection with multiphasic contrast-enhanced CT. Radiology. 213(1):92-6, 1999
                                                                                              17. Kamel IR et al: Imaging of abdominal manifestations of melanoma. Crit Rev Diagn Imaging. 39(6):447-86, 1998
                                                                                              18. Fishman EK et al: CT of malignant melanoma in the chest, abdomen, and musculoskeletal system. Radiographics. 10(4):603-20, 1990
                                                                                              19. Stutte H et al: Ultrasonographic diagnosis of melanoma metastases in liver, gallbladder, and spleen. J Ultrasound Med. 8(10):541-7, 1989
                                                                                              20. Daunt N et al: Metastatic melanoma in the biliary tree. Br J Radiol. 55(659):873-4, 1982