Small vessel calcification leading to end-organ ischemia
May result in rapidly fatal noncardiogenic edema
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Fehrmann A et al: Metastatic pulmonary calcification: first report of pulmonary calcium suppression using dual-energy CT. Radiol Case Rep. 15(7):900-3, 2020
Lakshmana Perumal N et al: An unusual cause of pulmonary calcification. BMJ Case Rep. 12(6), 2019
Taniwaki M et al: Severe metastatic pulmonary calcification. Am J Med. 132(10):e733-4, 2019
Belém LC et al: Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases. Radiol Bras. 50(4):231-6, 2017
Arrestier R et al: Successful treatment of lung calciphylaxis with sodium thiosulfate in a patient with sickle cell disease: a case report. Medicine (Baltimore). 95(6):e2768, 2016
Belém LC et al: Metastatic pulmonary calcification: state-of-the-art review focused on imaging findings. Respir Med. 108(5):668-76, 2014
Yasuo M et al: Progressive pulmonary calcification after successful renal transplantation. Intern Med. 47(3):161-4, 2008
Li YJ et al: Fulminant pulmonary calciphylaxis and metastatic calcification causing acute respiratory failure in a uremic patient. Am J Kidney Dis. 47(4):e47-53, 2006
Chung MJ et al: Metabolic lung disease: imaging and histopathologic findings. Eur J Radiol. 54(2):233-45, 2005
Hartman TE et al: Metastatic pulmonary calcification in patients with hypercalcemia: findings on chest radiographs and CT scans. AJR Am J Roentgenol. 162(4):799-802, 1994
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Metastatic pulmonary calcification (MPC)
Synonyms
Pulmonary calcinosis
Definitions
Pulmonary calcification
Dystrophic calcification
Calcium deposition in injured pulmonary parenchyma
Small vessel calcification leading to end-organ ischemia
May result in rapidly fatal noncardiogenic edema
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Fehrmann A et al: Metastatic pulmonary calcification: first report of pulmonary calcium suppression using dual-energy CT. Radiol Case Rep. 15(7):900-3, 2020
Lakshmana Perumal N et al: An unusual cause of pulmonary calcification. BMJ Case Rep. 12(6), 2019
Taniwaki M et al: Severe metastatic pulmonary calcification. Am J Med. 132(10):e733-4, 2019
Belém LC et al: Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases. Radiol Bras. 50(4):231-6, 2017
Arrestier R et al: Successful treatment of lung calciphylaxis with sodium thiosulfate in a patient with sickle cell disease: a case report. Medicine (Baltimore). 95(6):e2768, 2016
Belém LC et al: Metastatic pulmonary calcification: state-of-the-art review focused on imaging findings. Respir Med. 108(5):668-76, 2014
Yasuo M et al: Progressive pulmonary calcification after successful renal transplantation. Intern Med. 47(3):161-4, 2008
Li YJ et al: Fulminant pulmonary calciphylaxis and metastatic calcification causing acute respiratory failure in a uremic patient. Am J Kidney Dis. 47(4):e47-53, 2006
Chung MJ et al: Metabolic lung disease: imaging and histopathologic findings. Eur J Radiol. 54(2):233-45, 2005
Hartman TE et al: Metastatic pulmonary calcification in patients with hypercalcemia: findings on chest radiographs and CT scans. AJR Am J Roentgenol. 162(4):799-802, 1994
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