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Middle Ear Cholesterol Granuloma
H. Ric Harnsberger, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Cholesterol granuloma (CG)
            • Synonyms

              • Cholesterol cyst, "chocolate" cyst, blue-dome cyst
            • Definitions

              • Recurrent hemorrhage into middle ear (ME) cavity causes inflammatory mass of granulation tissue

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Polo R et al: Mastoid cholesterol granuloma with posterior cranial fossa compression. Otol Neurotol. 34(7):e103-4, 2013
                                          2. Shih TY et al: Erosive cholesterol granuloma. Otol Neurotol. 34(4):e26-7, 2013
                                          3. Ursick JA et al: Cholesterol granuloma. Ear Nose Throat J. 91(10):E31, 2012
                                          4. Matsuda Y et al: Analysis of surgical treatment for middle-ear cholesterol granuloma. J Laryngol Otol Suppl. (31):90-6, 2009
                                          5. Martin TP et al: A large and uncharacteristically aggressive cholesterol granuloma of the middle ear. J Laryngol Otol. 119(12):1001-3, 2005
                                          6. Murugasu E et al: Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss. Otol Neurotol. 25(3):231-5, 2004
                                          7. Jackler RK et al: A new theory to explain the genesis of petrous apex cholesterol granuloma. Otol Neurotol. 24(1):96-106; discussion 106, 2003
                                          8. Maeta M et al: Surgical intervention in middle-ear cholesterol granuloma. J Laryngol Otol. 117(5):344-8, 2003
                                          9. Friedmann I et al: The ultrastructure of cholesterol granuloma of the middle ear: an electron microscope study. The Journal of Laryngology and Otology, 1979; Vol. 93, pp. 433-442. J Laryngol Otol. 116(11):877-81, 2002
                                          10. Kosling S et al: CT and MR imaging after middle ear surgery. Eur J Radiol. 40(2):113-8, 2001
                                          11. Campos A et al: Cholesterol granuloma of the middle ear: report of 5 cases. Acta Otorhinolaryngol Belg. 50(2):125-9, 1996
                                          12. Martin N et al: Cholesterol granulomas of the middle ear cavities: MR imaging. Radiology. 172(2):521-5, 1989
                                          13. Palva T et al: Large cholesterol granuloma cysts in the mastoid. Clinical and histopathologic findings. Arch Otolaryngol. 111(12):786-91, 1985
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Cholesterol granuloma (CG)
                                                    • Synonyms

                                                      • Cholesterol cyst, "chocolate" cyst, blue-dome cyst
                                                    • Definitions

                                                      • Recurrent hemorrhage into middle ear (ME) cavity causes inflammatory mass of granulation tissue

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              • Image Interpretation Pearls

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Polo R et al: Mastoid cholesterol granuloma with posterior cranial fossa compression. Otol Neurotol. 34(7):e103-4, 2013
                                                                                  2. Shih TY et al: Erosive cholesterol granuloma. Otol Neurotol. 34(4):e26-7, 2013
                                                                                  3. Ursick JA et al: Cholesterol granuloma. Ear Nose Throat J. 91(10):E31, 2012
                                                                                  4. Matsuda Y et al: Analysis of surgical treatment for middle-ear cholesterol granuloma. J Laryngol Otol Suppl. (31):90-6, 2009
                                                                                  5. Martin TP et al: A large and uncharacteristically aggressive cholesterol granuloma of the middle ear. J Laryngol Otol. 119(12):1001-3, 2005
                                                                                  6. Murugasu E et al: Invasive middle ear cholesterol granuloma involving the basal turn of the cochlea with profound sensorineural hearing loss. Otol Neurotol. 25(3):231-5, 2004
                                                                                  7. Jackler RK et al: A new theory to explain the genesis of petrous apex cholesterol granuloma. Otol Neurotol. 24(1):96-106; discussion 106, 2003
                                                                                  8. Maeta M et al: Surgical intervention in middle-ear cholesterol granuloma. J Laryngol Otol. 117(5):344-8, 2003
                                                                                  9. Friedmann I et al: The ultrastructure of cholesterol granuloma of the middle ear: an electron microscope study. The Journal of Laryngology and Otology, 1979; Vol. 93, pp. 433-442. J Laryngol Otol. 116(11):877-81, 2002
                                                                                  10. Kosling S et al: CT and MR imaging after middle ear surgery. Eur J Radiol. 40(2):113-8, 2001
                                                                                  11. Campos A et al: Cholesterol granuloma of the middle ear: report of 5 cases. Acta Otorhinolaryngol Belg. 50(2):125-9, 1996
                                                                                  12. Martin N et al: Cholesterol granulomas of the middle ear cavities: MR imaging. Radiology. 172(2):521-5, 1989
                                                                                  13. Palva T et al: Large cholesterol granuloma cysts in the mastoid. Clinical and histopathologic findings. Arch Otolaryngol. 111(12):786-91, 1985