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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Middle lobe syndrome (MLS)
- Right middle lobe (RML)
Synonyms
- Right MLS
Definitions
- Chronic or recurrent nonobstructive middle lobe atelectasis or consolidation
- Identified on serial imaging
- RML prone to atelectasis and airspace disease
- Longer, narrower bronchus
- Acute take-off from bronchus intermedius
- RML bronchus surrounded by lymph nodes; convergence of upper and lower lobe lymphatics
- Minor fissure prevents collateral ventilation
- Chronic or recurrent nonobstructive middle lobe atelectasis or consolidation
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Diagnosis
Treatment
Selected References
- Rashid A et al: Infectious causes of right middle lobe syndrome. Cancer Control. 24(1):60-5, 2017
- Romagnoli V et al: Middle lobe syndrome in children today. Paediatr Respir Rev. 15(2):188-93, 2014
- Gudbjartsson T et al: Middle lobe syndrome: a review of clinicopathological features, diagnosis and treatment. Respiration. 84(1):80-6, 2012
- Gudmundsson G et al: Middle lobe syndrome. Am Fam Physician. 53(8):2547-50, 1996
- Kwon KY et al: Middle lobe syndrome: a clinicopathological study of 21 patients. Hum Pathol. 26(3):302-7, 1995
- Wagner RB et al: Middle lobe syndrome. Ann Thorac Surg. 35(6):679-86, 1983
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Middle lobe syndrome (MLS)
- Right middle lobe (RML)
Synonyms
- Right MLS
Definitions
- Chronic or recurrent nonobstructive middle lobe atelectasis or consolidation
- Identified on serial imaging
- RML prone to atelectasis and airspace disease
- Longer, narrower bronchus
- Acute take-off from bronchus intermedius
- RML bronchus surrounded by lymph nodes; convergence of upper and lower lobe lymphatics
- Minor fissure prevents collateral ventilation
- Chronic or recurrent nonobstructive middle lobe atelectasis or consolidation
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Diagnosis
Treatment
Selected References
- Rashid A et al: Infectious causes of right middle lobe syndrome. Cancer Control. 24(1):60-5, 2017
- Romagnoli V et al: Middle lobe syndrome in children today. Paediatr Respir Rev. 15(2):188-93, 2014
- Gudbjartsson T et al: Middle lobe syndrome: a review of clinicopathological features, diagnosis and treatment. Respiration. 84(1):80-6, 2012
- Gudmundsson G et al: Middle lobe syndrome. Am Fam Physician. 53(8):2547-50, 1996
- Kwon KY et al: Middle lobe syndrome: a clinicopathological study of 21 patients. Hum Pathol. 26(3):302-7, 1995
- Wagner RB et al: Middle lobe syndrome. Ann Thorac Surg. 35(6):679-86, 1983
