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Miscellaneous Benign Mesenchymal Tumors
Miral D. Jhaveri, MD, MBA; Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Benign mesenchymal tumors (BMTs)
                  • Includes chondroma (CD), osteochondroma (OCD), osteoma (OST), and many others
              • Synonyms

                • Benign nonmeningothelial tumors
              • Definitions

                • Nonmenigotheliomatous mesenchymal benign neoplasm
                  • Typically dura, skull, &/or scalp lesion

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              Selected References

                                              1. Pons Escoda A et al: Imaging of skull vault tumors in adults. Insights Imaging. 11(1):23, 2020
                                              2. Seo DH et al: Protruding meningioma of the forehead with extensive hyperostosis mimicking skull osteoma. J Craniofac Surg. ePub, 2020
                                              3. Elhakeem AAS et al: Chondroma of the falx cerebri: a case report and review of literature. Neuropathology. 39(6):461-6, 2019
                                              4. Oushy S et al: Skull base enchondroma and chondrosarcoma in Ollier disease and Maffucci syndrome. World Neurosurg. 130:e356-61, 2019
                                              5. Sullivan JC et al: Intracranial dural parafalcine chondroma: case report and systematic review of the literature. World Neurosurg. 122:1-7, 2019
                                              6. da Costa ED et al: Clinical implications, diagnosis, and treatment of a giant frontoethmoid osteoma. Gen Dent. 66(5):e1-4, 2018
                                              7. Zanotti MC et al: A multidisciplinary approach for the treatment of young patients with suprasellar osteochondroma. Childs Nerv Syst. 34(3):559-63, 2018
                                              8. Yudoyono F et al: Surgical management of giant skull osteomas. Asian J Neurosurg. 12(3):408-11, 2017
                                              9. Lee DH et al: Characteristics of paranasal sinus osteoma and treatment outcomes. Acta Otolaryngol. 1-6, 2015
                                              10. Atalay FO et al: Intracranial extra-axial chondroma: a case report. J Nippon Med Sch. 81(1):35-9, 2014
                                              11. Sanal HT et al: Bumps over cheeks. Skeletal Radiol. 43(2):233, 267-8, 2014
                                              12. Wen G et al: Solitary fibrous tumor of the central nervous system: report of 2 cases and review of literature. Int J Clin Exp Pathol. 7(6):3444-8, 2014
                                              13. Fountas KN et al: Intracranial falx chondroma: literature review and a case report. Clin Neurol Neurosurg. 110(1):8-13, 2008
                                              14. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Benign mesenchymal tumors (BMTs)
                                                              • Includes chondroma (CD), osteochondroma (OCD), osteoma (OST), and many others
                                                          • Synonyms

                                                            • Benign nonmeningothelial tumors
                                                          • Definitions

                                                            • Nonmenigotheliomatous mesenchymal benign neoplasm
                                                              • Typically dura, skull, &/or scalp lesion

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          Selected References

                                                                                          1. Pons Escoda A et al: Imaging of skull vault tumors in adults. Insights Imaging. 11(1):23, 2020
                                                                                          2. Seo DH et al: Protruding meningioma of the forehead with extensive hyperostosis mimicking skull osteoma. J Craniofac Surg. ePub, 2020
                                                                                          3. Elhakeem AAS et al: Chondroma of the falx cerebri: a case report and review of literature. Neuropathology. 39(6):461-6, 2019
                                                                                          4. Oushy S et al: Skull base enchondroma and chondrosarcoma in Ollier disease and Maffucci syndrome. World Neurosurg. 130:e356-61, 2019
                                                                                          5. Sullivan JC et al: Intracranial dural parafalcine chondroma: case report and systematic review of the literature. World Neurosurg. 122:1-7, 2019
                                                                                          6. da Costa ED et al: Clinical implications, diagnosis, and treatment of a giant frontoethmoid osteoma. Gen Dent. 66(5):e1-4, 2018
                                                                                          7. Zanotti MC et al: A multidisciplinary approach for the treatment of young patients with suprasellar osteochondroma. Childs Nerv Syst. 34(3):559-63, 2018
                                                                                          8. Yudoyono F et al: Surgical management of giant skull osteomas. Asian J Neurosurg. 12(3):408-11, 2017
                                                                                          9. Lee DH et al: Characteristics of paranasal sinus osteoma and treatment outcomes. Acta Otolaryngol. 1-6, 2015
                                                                                          10. Atalay FO et al: Intracranial extra-axial chondroma: a case report. J Nippon Med Sch. 81(1):35-9, 2014
                                                                                          11. Sanal HT et al: Bumps over cheeks. Skeletal Radiol. 43(2):233, 267-8, 2014
                                                                                          12. Wen G et al: Solitary fibrous tumor of the central nervous system: report of 2 cases and review of literature. Int J Clin Exp Pathol. 7(6):3444-8, 2014
                                                                                          13. Fountas KN et al: Intracranial falx chondroma: literature review and a case report. Clin Neurol Neurosurg. 110(1):8-13, 2008
                                                                                          14. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007