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Morton Neuroma
Stephanie A. Bernard, MDCatherine C. Roberts, MDEric Walker, MD, MHA, FACR, FACHE
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Plantar neuroma, localized interdigital neuritis, Morton toe, Morton node, interdigital neuralgia, Morton metatarsalgia
          • Definitions

            • Nonneoplastic, perineural fibrosis around plantar digital nerve

          IMAGING

          • General Features

            • Radiographic Findings

              • MR Findings

                • Imaging Recommendations

                  • CT Findings

                    • Ultrasonographic Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Treatment

                                    Selected References

                                    1. Galley J et al: The Vulcan salute sign: a non-sensitive but specific sign for Morton's neuroma on radiographs. Skeletal Radiol. 51(3):581-6, 2022
                                    2. Umans H et al: MRI of lesser metatarsophalangeal joint plantar plate tears and associated adjacent interspace lesions. Skeletal Radiol. 43(10):1361-8, 2014
                                    3. Yablon CM: Ultrasound-guided interventions of the foot and ankle. Semin Musculoskelet Radiol. 17(1):60-8, 2013
                                    4. Espinosa N et al: Morton neuroma: MR imaging after resection--postoperative MR and histologic findings in asymptomatic and symptomatic intermetatarsal spaces. Radiology. 255(3):850-6, 2010
                                    5. Weiss SW et al: Benign tumors of peripheral nerves In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 832-3, 2008
                                    6. Lee MJ et al: Morton neuroma: evaluated with ultrasonography and MR imaging. Korean J Radiol. 8(2):148-55, 2007
                                    7. Kransdorf MJ et al: Neurogenic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 331-4, 2006
                                    8. Zanetti M et al: MR imaging of the forefoot: Morton neuroma and differential diagnoses. Semin Musculoskelet Radiol. 9(3):175-86, 2005
                                    9. Weishaupt D et al: Morton neuroma: MR imaging in prone, supine, and upright weight-bearing body positions. Radiology. 226(3):849-56, 2003
                                    10. Ashman CJ et al: Forefoot pain involving the metatarsal region: differential diagnosis with MR imaging. Radiographics. 21(6):1425-40, 2001
                                    11. Murphey MD et al: From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 19(5):1253-80, 1999
                                    12. Zanetti M et al: Morton neuroma: effect of MR imaging findings on diagnostic thinking and therapeutic decisions. Radiology. 213(2):583-8, 1999
                                    13. Zanetti M et al: Morton neuroma and fluid in the intermetatarsal bursae on MR images of 70 asymptomatic volunteers. Radiology. 203(2):516-20, 1997
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Synonyms

                                              • Plantar neuroma, localized interdigital neuritis, Morton toe, Morton node, interdigital neuralgia, Morton metatarsalgia
                                            • Definitions

                                              • Nonneoplastic, perineural fibrosis around plantar digital nerve

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • MR Findings

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • Ultrasonographic Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Galley J et al: The Vulcan salute sign: a non-sensitive but specific sign for Morton's neuroma on radiographs. Skeletal Radiol. 51(3):581-6, 2022
                                                                      2. Umans H et al: MRI of lesser metatarsophalangeal joint plantar plate tears and associated adjacent interspace lesions. Skeletal Radiol. 43(10):1361-8, 2014
                                                                      3. Yablon CM: Ultrasound-guided interventions of the foot and ankle. Semin Musculoskelet Radiol. 17(1):60-8, 2013
                                                                      4. Espinosa N et al: Morton neuroma: MR imaging after resection--postoperative MR and histologic findings in asymptomatic and symptomatic intermetatarsal spaces. Radiology. 255(3):850-6, 2010
                                                                      5. Weiss SW et al: Benign tumors of peripheral nerves In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 832-3, 2008
                                                                      6. Lee MJ et al: Morton neuroma: evaluated with ultrasonography and MR imaging. Korean J Radiol. 8(2):148-55, 2007
                                                                      7. Kransdorf MJ et al: Neurogenic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 331-4, 2006
                                                                      8. Zanetti M et al: MR imaging of the forefoot: Morton neuroma and differential diagnoses. Semin Musculoskelet Radiol. 9(3):175-86, 2005
                                                                      9. Weishaupt D et al: Morton neuroma: MR imaging in prone, supine, and upright weight-bearing body positions. Radiology. 226(3):849-56, 2003
                                                                      10. Ashman CJ et al: Forefoot pain involving the metatarsal region: differential diagnosis with MR imaging. Radiographics. 21(6):1425-40, 2001
                                                                      11. Murphey MD et al: From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 19(5):1253-80, 1999
                                                                      12. Zanetti M et al: Morton neuroma: effect of MR imaging findings on diagnostic thinking and therapeutic decisions. Radiology. 213(2):583-8, 1999
                                                                      13. Zanetti M et al: Morton neuroma and fluid in the intermetatarsal bursae on MR images of 70 asymptomatic volunteers. Radiology. 203(2):516-20, 1997