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Mucinous Cystadenoma
Akram M. Shaaban, MBBCh; Winnie Hahn, MD; Deborah Levine, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Benign ovarian epithelial neoplasms with gastrointestinal or müllerian-type mucinous epithelium

        IMAGING

        • General Features

          • CT Findings

            • MR Findings

              • Ultrasonographic Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Marko J et al: Mucinous neoplasms of the ovary: radiologic-pathologic correlation. Radiographics. 39(4):982-97, 2019
                                      2. Timor-Tritsch IE et al: New sonographic marker of borderline ovarian tumor: microcystic pattern of papillae and solid components. Ultrasound Obstet Gynecol. 54(3):395-402, 2019
                                      3. Lee SS et al: The stained glass window appearance. Abdom Radiol (NY). 41(2):342-3, 2016
                                      4. Zhao SH et al: MRI in differentiating ovarian borderline from benign mucinous cystadenoma: pathological correlation. J Magn Reson Imaging. 39(1):162-6, 2014
                                      5. Hunter SM et al: Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations. Clin Cancer Res. 18(19):5267-77, 2012
                                      6. Thomas RL et al: Bilateral mucinous cystadenomas and massive edema of the ovaries in a virilized adolescent girl. Obstet Gynecol. 120(2 Pt 2):473-6, 2012
                                      7. Aragon L et al: Angiosarcoma of the ovary arising in a mucinous cystadenoma. J Clin Ultrasound. 39(6):351-5, 2011
                                      8. Okamoto Y et al: Malignant or borderline mucinous cystic neoplasms have a larger number of loculi than mucinous cystadenoma: a retrospective study with MR. J Magn Reson Imaging. 26(1):94-9, 2007
                                      9. Ylisaukko-oja SK et al: Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma. Eur J Hum Genet. 14(7):880-3, 2006
                                      10. Hart WR: Mucinous tumors of the ovary: a review. Int J Gynecol Pathol. 24(1):4-25, 2005
                                      11. Okada S et al: Calcifications in mucinous and serous cystic ovarian tumors. J Nippon Med Sch. 72(1):29-33, 2005
                                      12. Chao A et al: Abdominal compartment syndrome secondary to ovarian mucinous cystadenoma. Obstet Gynecol. 104(5 Pt 2):1180-2, 2004
                                      13. Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
                                      14. Hussain SM et al: MR imaging features of pelvic mucinous carcinomas. Eur Radiol. 10(6):885-91, 2000
                                      15. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                      16. Tanaka YO et al: Differential diagnosis of gynaecological "stained glass" tumours on MRI. Br J Radiol. 72(856):414-20, 1999
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Definitions

                                              • Benign ovarian epithelial neoplasms with gastrointestinal or müllerian-type mucinous epithelium

                                            IMAGING

                                            • General Features

                                              • CT Findings

                                                • MR Findings

                                                  • Ultrasonographic Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Marko J et al: Mucinous neoplasms of the ovary: radiologic-pathologic correlation. Radiographics. 39(4):982-97, 2019
                                                                          2. Timor-Tritsch IE et al: New sonographic marker of borderline ovarian tumor: microcystic pattern of papillae and solid components. Ultrasound Obstet Gynecol. 54(3):395-402, 2019
                                                                          3. Lee SS et al: The stained glass window appearance. Abdom Radiol (NY). 41(2):342-3, 2016
                                                                          4. Zhao SH et al: MRI in differentiating ovarian borderline from benign mucinous cystadenoma: pathological correlation. J Magn Reson Imaging. 39(1):162-6, 2014
                                                                          5. Hunter SM et al: Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations. Clin Cancer Res. 18(19):5267-77, 2012
                                                                          6. Thomas RL et al: Bilateral mucinous cystadenomas and massive edema of the ovaries in a virilized adolescent girl. Obstet Gynecol. 120(2 Pt 2):473-6, 2012
                                                                          7. Aragon L et al: Angiosarcoma of the ovary arising in a mucinous cystadenoma. J Clin Ultrasound. 39(6):351-5, 2011
                                                                          8. Okamoto Y et al: Malignant or borderline mucinous cystic neoplasms have a larger number of loculi than mucinous cystadenoma: a retrospective study with MR. J Magn Reson Imaging. 26(1):94-9, 2007
                                                                          9. Ylisaukko-oja SK et al: Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma. Eur J Hum Genet. 14(7):880-3, 2006
                                                                          10. Hart WR: Mucinous tumors of the ovary: a review. Int J Gynecol Pathol. 24(1):4-25, 2005
                                                                          11. Okada S et al: Calcifications in mucinous and serous cystic ovarian tumors. J Nippon Med Sch. 72(1):29-33, 2005
                                                                          12. Chao A et al: Abdominal compartment syndrome secondary to ovarian mucinous cystadenoma. Obstet Gynecol. 104(5 Pt 2):1180-2, 2004
                                                                          13. Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
                                                                          14. Hussain SM et al: MR imaging features of pelvic mucinous carcinomas. Eur Radiol. 10(6):885-91, 2000
                                                                          15. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                                                          16. Tanaka YO et al: Differential diagnosis of gynaecological "stained glass" tumours on MRI. Br J Radiol. 72(856):414-20, 1999