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Mucoepidermoid Carcinoma, Airways
Christopher M. Walker, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Mucoepidermoid carcinoma (MEC)
              • Definitions

                • Primary malignant neoplasm arising from bronchial glands in tracheobronchial tree and lungs
                • 0.1-0.2% of all primary pulmonary malignant neoplasms
                • Formerly grouped with adenoid cystic carcinoma, carcinoid, and mixed tumor under outdated term "bronchial adenoma"

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • Staging, Grading, & Classification

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Elnayal A et al: Primary salivary gland-type lung cancer: imaging and clinical predictors of outcome. AJR Am J Roentgenol. 201(1):W57-63, 2013
                                          2. Li X et al: Mucoepidermoid carcinoma of the lung: common findings and unusual appearances on CT. Clin Imaging. 36(1):8-13, 2012
                                          3. Xi JJ et al: Primary pulmonary mucoepidermoid carcinoma: an analysis of 21 cases. World J Surg Oncol. 10:232, 2012
                                          4. Kang DY et al: Primary salivary gland-type lung cancer: Surgical outcomes. Lung Cancer. 72(2):250-4, 2011
                                          5. Chin CH et al: Prognostic factors of tracheobronchial mucoepidermoid carcinoma--15 years experience. Respirology. 13(2):275-80, 2008
                                          6. Ishizumi T et al: Mucoepidermoid carcinoma of the lung: high-resolution CT and histopathologic findings in five cases. Lung Cancer. 60(1):125-31, 2008
                                          7. Molina JR et al: Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors. Cancer. 110(10):2253-9, 2007
                                          8. Gaissert HA et al: Uncommon primary tracheal tumors. Ann Thorac Surg. 82(1):268-72; discussion 272-3, 2006
                                          9. Kim TS et al: Sialadenoid tumors of the respiratory tract: radiologic-pathologic correlation. AJR Am J Roentgenol. 177(5):1145-50, 2001
                                          10. Yousem SA et al: Mucoepidermoid tumors of the lung. Cancer. 60(6):1346-52, 1987
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Mucoepidermoid carcinoma (MEC)
                                                      • Definitions

                                                        • Primary malignant neoplasm arising from bronchial glands in tracheobronchial tree and lungs
                                                        • 0.1-0.2% of all primary pulmonary malignant neoplasms
                                                        • Formerly grouped with adenoid cystic carcinoma, carcinoid, and mixed tumor under outdated term "bronchial adenoma"

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • Staging, Grading, & Classification

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Elnayal A et al: Primary salivary gland-type lung cancer: imaging and clinical predictors of outcome. AJR Am J Roentgenol. 201(1):W57-63, 2013
                                                                                  2. Li X et al: Mucoepidermoid carcinoma of the lung: common findings and unusual appearances on CT. Clin Imaging. 36(1):8-13, 2012
                                                                                  3. Xi JJ et al: Primary pulmonary mucoepidermoid carcinoma: an analysis of 21 cases. World J Surg Oncol. 10:232, 2012
                                                                                  4. Kang DY et al: Primary salivary gland-type lung cancer: Surgical outcomes. Lung Cancer. 72(2):250-4, 2011
                                                                                  5. Chin CH et al: Prognostic factors of tracheobronchial mucoepidermoid carcinoma--15 years experience. Respirology. 13(2):275-80, 2008
                                                                                  6. Ishizumi T et al: Mucoepidermoid carcinoma of the lung: high-resolution CT and histopathologic findings in five cases. Lung Cancer. 60(1):125-31, 2008
                                                                                  7. Molina JR et al: Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors. Cancer. 110(10):2253-9, 2007
                                                                                  8. Gaissert HA et al: Uncommon primary tracheal tumors. Ann Thorac Surg. 82(1):268-72; discussion 272-3, 2006
                                                                                  9. Kim TS et al: Sialadenoid tumors of the respiratory tract: radiologic-pathologic correlation. AJR Am J Roentgenol. 177(5):1145-50, 2001
                                                                                  10. Yousem SA et al: Mucoepidermoid tumors of the lung. Cancer. 60(6):1346-52, 1987