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Mucoepidermoid Carcinoma
Sonia L. Betancourt-Cuellar, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Mucoepidermoid carcinoma (MEC)
              • Definitions

                • Primary pulmonary salivary gland-type tumors: MEC and adenoid cystic carcinoma
                  • Origin in large airway bronchial glands: Functionally equivalent to oropharyngeal salivary glands
                  • Represent < 1% of all lung cancers
                  • MEC and adenoid cystic carcinoma are most common salivary gland-type tumors

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Ding CY et al: [(18)F-fluorodeoxy glucose positron emission tomography/computed tomography manifestation and clinical characteristics of primary salivary gland-type lung cancer.] Zhonghua Zhong Liu Za Zhi. 41(4):288-93, 2019
                                          2. Garg PK et al: Primary salivary gland-type tumors of the lung: a systematic review and pooled analysis. Lung India. 36(2):118-22, 2019
                                          3. Han X et al: Radiological and clinical features and outcomes of patients with primary pulmonary salivary gland-type tumors. Can Respir J. 2019:1475024, 2019
                                          4. Kalhor N et al: Pulmonary mucoepidermoid carcinoma: diagnosis and treatment. Expert Rev Respir Med. 12(3):249-55, 2018
                                          5. Park B et al: Prediction of pathologic grade and prognosis in mucoepidermoid carcinoma of the lung using ¹⁸F-FDG PET/CT. Korean J Radiol. 16(4):929-35, 2015
                                          6. Li X et al: Mucoepidermoid carcinoma of the lung: common findings and unusual appearances on CT. Clin Imaging. 36(1):8-13, 2012
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Mucoepidermoid carcinoma (MEC)
                                                      • Definitions

                                                        • Primary pulmonary salivary gland-type tumors: MEC and adenoid cystic carcinoma
                                                          • Origin in large airway bronchial glands: Functionally equivalent to oropharyngeal salivary glands
                                                          • Represent < 1% of all lung cancers
                                                          • MEC and adenoid cystic carcinoma are most common salivary gland-type tumors

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Ding CY et al: [(18)F-fluorodeoxy glucose positron emission tomography/computed tomography manifestation and clinical characteristics of primary salivary gland-type lung cancer.] Zhonghua Zhong Liu Za Zhi. 41(4):288-93, 2019
                                                                                  2. Garg PK et al: Primary salivary gland-type tumors of the lung: a systematic review and pooled analysis. Lung India. 36(2):118-22, 2019
                                                                                  3. Han X et al: Radiological and clinical features and outcomes of patients with primary pulmonary salivary gland-type tumors. Can Respir J. 2019:1475024, 2019
                                                                                  4. Kalhor N et al: Pulmonary mucoepidermoid carcinoma: diagnosis and treatment. Expert Rev Respir Med. 12(3):249-55, 2018
                                                                                  5. Park B et al: Prediction of pathologic grade and prognosis in mucoepidermoid carcinoma of the lung using ¹⁸F-FDG PET/CT. Korean J Radiol. 16(4):929-35, 2015
                                                                                  6. Li X et al: Mucoepidermoid carcinoma of the lung: common findings and unusual appearances on CT. Clin Imaging. 36(1):8-13, 2012