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Multilocular Cystic Nephroma
Alexander J. Towbin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Multilocular cystic nephroma (MLCN); cystic partially differentiated nephroblastoma (CPDN)
            • Definitions

              • Benign mixed mesenchymal & epithelial renal neoplasm

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Faure A et al: DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know. J Pediatr Urol. 12(1):5-10, 2016
                                              2. Wu MK et al: Evolution of renal cysts to anaplastic sarcoma of kidney in a child with DICER1 syndrome. Pediatr Blood Cancer. 63(7):1272-5, 2016
                                              3. Granja MF et al: Multilocular cystic nephroma: a systematic literature review of the radiologic and clinical rindings. AJR Am J Roentgenol. 205(6):1188-93, 2015
                                              4. Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
                                              5. Silver IM et al: Best cases from the AFIP: Multilocular cystic renal tumor: cystic nephroma. Radiographics. 28(4):1221-5; discussion 1225-6, 2008
                                              6. Hopkins JK et al: Best cases from the AFIP: cystic nephroma. Radiographics. 24(2):589-93, 2004
                                              7. Agrons GA et al: Multilocular cystic renal tumor in children: radiologic-pathologic correlation. Radiographics. 15(3):653-69, 1995
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Multilocular cystic nephroma (MLCN); cystic partially differentiated nephroblastoma (CPDN)
                                                        • Definitions

                                                          • Benign mixed mesenchymal & epithelial renal neoplasm

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Ultrasonographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Faure A et al: DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know. J Pediatr Urol. 12(1):5-10, 2016
                                                                                          2. Wu MK et al: Evolution of renal cysts to anaplastic sarcoma of kidney in a child with DICER1 syndrome. Pediatr Blood Cancer. 63(7):1272-5, 2016
                                                                                          3. Granja MF et al: Multilocular cystic nephroma: a systematic literature review of the radiologic and clinical rindings. AJR Am J Roentgenol. 205(6):1188-93, 2015
                                                                                          4. Doros LA et al: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol. 27(9):1267-80, 2014
                                                                                          5. Silver IM et al: Best cases from the AFIP: Multilocular cystic renal tumor: cystic nephroma. Radiographics. 28(4):1221-5; discussion 1225-6, 2008
                                                                                          6. Hopkins JK et al: Best cases from the AFIP: cystic nephroma. Radiographics. 24(2):589-93, 2004
                                                                                          7. Agrons GA et al: Multilocular cystic renal tumor in children: radiologic-pathologic correlation. Radiographics. 15(3):653-69, 1995