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Multiple Myeloma
Chris Hanrahan, MD, PhD
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4

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Routes Spread

        • General Features

          • Gross Pathology

            • Microscopic Features

              IMAGING FINDINGS

              • Detection

                • Staging

                  CLINICAL ISSUES

                  • Presentation

                    • Cancer History

                      • Treatment Options

                        REPORTING CHECKLIST

                        • RSS

                          • CT

                            • WB MR vs. Spine/Pelvis MR

                              • FDG PET/CT

                                • Imaging After Treatment

                                  Selected References

                                  1. Filonzi G et al: A comparison of different staging systems for multiple myeloma: can the MRI pattern play a prognostic role? AJR Am J Roentgenol. 209(1):152-8, 2017
                                  2. Dimopoulos MA et al: Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement. J Clin Oncol. 33(6):657-64, 2015
                                  3. Palumbo A et al: Revised International Staging System for Multiple Myeloma: a report from International Myeloma Working Group. J Clin Oncol. 33(26):2863-9, 2015
                                  4. Hanrahan CJ et al: Current concepts in the evaluation of multiple myeloma with MR imaging and FDG PET/CT. Radiographics. 30(1):127-42, 2010
                                  5. Dimopoulos M et al: International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma. Leukemia. 23(9):1545-56, 2009
                                  6. Shortt CP et al: Whole-Body MRI versus PET in assessment of multiple myeloma disease activity. AJR Am J Roentgenol. 192(4):980-6, 2009
                                  7. Baur-Melnyk A et al: Whole-body MRI versus whole-body MDCT for staging of multiple myeloma. AJR Am J Roentgenol. 190(4):1097-104, 2008
                                  8. Kyle RA et al: Multiple myeloma. Blood. 111(6):2962-72, 2008
                                  9. Avet-Loiseau H et al: Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. Blood. 109(8):3489-95, 2007
                                  10. Breyer RJ 3rd et al: Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 35(9):632-40, 2006
                                  11. Durie BG: The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 42(11):1539-43, 2006
                                  12. Greipp PR et al: International staging system for multiple myeloma. J Clin Oncol. 2005 May 20;23(15):3412-20. Epub 2005 Apr 4. Erratum in: J Clin Oncol. 23(25):6281, 2005
                                  13. Angtuaco EJ et al: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 231(1):11-23, 2004
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  OVERVIEW

                                  • General Comments

                                    • Classification

                                      PATHOLOGY

                                      • Routes Spread

                                        • General Features

                                          • Gross Pathology

                                            • Microscopic Features

                                              IMAGING FINDINGS

                                              • Detection

                                                • Staging

                                                  CLINICAL ISSUES

                                                  • Presentation

                                                    • Cancer History

                                                      • Treatment Options

                                                        REPORTING CHECKLIST

                                                        • RSS

                                                          • CT

                                                            • WB MR vs. Spine/Pelvis MR

                                                              • FDG PET/CT

                                                                • Imaging After Treatment

                                                                  Selected References

                                                                  1. Filonzi G et al: A comparison of different staging systems for multiple myeloma: can the MRI pattern play a prognostic role? AJR Am J Roentgenol. 209(1):152-8, 2017
                                                                  2. Dimopoulos MA et al: Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement. J Clin Oncol. 33(6):657-64, 2015
                                                                  3. Palumbo A et al: Revised International Staging System for Multiple Myeloma: a report from International Myeloma Working Group. J Clin Oncol. 33(26):2863-9, 2015
                                                                  4. Hanrahan CJ et al: Current concepts in the evaluation of multiple myeloma with MR imaging and FDG PET/CT. Radiographics. 30(1):127-42, 2010
                                                                  5. Dimopoulos M et al: International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma. Leukemia. 23(9):1545-56, 2009
                                                                  6. Shortt CP et al: Whole-Body MRI versus PET in assessment of multiple myeloma disease activity. AJR Am J Roentgenol. 192(4):980-6, 2009
                                                                  7. Baur-Melnyk A et al: Whole-body MRI versus whole-body MDCT for staging of multiple myeloma. AJR Am J Roentgenol. 190(4):1097-104, 2008
                                                                  8. Kyle RA et al: Multiple myeloma. Blood. 111(6):2962-72, 2008
                                                                  9. Avet-Loiseau H et al: Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. Blood. 109(8):3489-95, 2007
                                                                  10. Breyer RJ 3rd et al: Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 35(9):632-40, 2006
                                                                  11. Durie BG: The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 42(11):1539-43, 2006
                                                                  12. Greipp PR et al: International staging system for multiple myeloma. J Clin Oncol. 2005 May 20;23(15):3412-20. Epub 2005 Apr 4. Erratum in: J Clin Oncol. 23(25):6281, 2005
                                                                  13. Angtuaco EJ et al: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 231(1):11-23, 2004