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Mycobacterial Avium Complex
Helen T. Winer-Muram, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Nontuberculous mycobacteria (NTM)
            • Nontuberculous mycobacterial infection (NTMBI)
            • Mycobacterium avium-intracellulare complex (MAC)
          • Definitions

            • NTMBI, most commonly caused by MAC
              • NTMBI also caused by M. kansasii, M. xenopi, M. fortuitum, M. chelonae, M. abscessus
            • 5 types of disease
              • Cavitary form (classic)
              • Bronchiectatic form (nonclassic)
              • Solitary or multiple pulmonary nodules
              • Pneumonia in immunosuppressed host
              • Hot tub lung: Hypersensitivity pneumonitis to NTM

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Diagnosis

                                • Natural History & Prognosis

                                  • Treatment

                                    Selected References

                                    1. Martinez S et al: The many faces of pulmonary nontuberculous mycobacterial infection. AJR Am J Roentgenol. 189(1):177-86, 2007
                                    2. Hanak V et al: Hot tub lung: presenting features and clinical course of 21 patients. Respir Med. 100(4):610-5, 2006
                                    3. Jeong YJ et al: Nontuberculous mycobacterial pulmonary infection in immunocompetent patients: comparison of thin-section CT and histopathologic findings. Radiology. 231(3):880-6, 2004
                                    4. Wittram C et al: Mycobacterium avium complex lung disease in immunocompetent patients: radiography-CT correlation. Br J Radiol. 75(892):340-4, 2002
                                    5. Erasmus JJ et al: Pulmonary nontuberculous mycobacterial infection: radiologic manifestations. Radiographics. 19(6):1487-505, 1999
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Nontuberculous mycobacteria (NTM)
                                              • Nontuberculous mycobacterial infection (NTMBI)
                                              • Mycobacterium avium-intracellulare complex (MAC)
                                            • Definitions

                                              • NTMBI, most commonly caused by MAC
                                                • NTMBI also caused by M. kansasii, M. xenopi, M. fortuitum, M. chelonae, M. abscessus
                                              • 5 types of disease
                                                • Cavitary form (classic)
                                                • Bronchiectatic form (nonclassic)
                                                • Solitary or multiple pulmonary nodules
                                                • Pneumonia in immunosuppressed host
                                                • Hot tub lung: Hypersensitivity pneumonitis to NTM

                                            IMAGING

                                            • General Features

                                              • Radiographic Findings

                                                • CT Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Gross Pathologic & Surgical Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Diagnosis

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Martinez S et al: The many faces of pulmonary nontuberculous mycobacterial infection. AJR Am J Roentgenol. 189(1):177-86, 2007
                                                                      2. Hanak V et al: Hot tub lung: presenting features and clinical course of 21 patients. Respir Med. 100(4):610-5, 2006
                                                                      3. Jeong YJ et al: Nontuberculous mycobacterial pulmonary infection in immunocompetent patients: comparison of thin-section CT and histopathologic findings. Radiology. 231(3):880-6, 2004
                                                                      4. Wittram C et al: Mycobacterium avium complex lung disease in immunocompetent patients: radiography-CT correlation. Br J Radiol. 75(892):340-4, 2002
                                                                      5. Erasmus JJ et al: Pulmonary nontuberculous mycobacterial infection: radiologic manifestations. Radiographics. 19(6):1487-505, 1999