Clonal B-lymphocyte neoplasm of terminally differentiated plasma cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Other Modality Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Oka S et al: Successful treatment with pomalidomide and intrathecal injections for central nervous system plasmacytoma in a patient under haemodialysis. J Clin Pharm Ther. 45(1):221-5, 2020
Elhassadi E et al: Durable treatment response of relapsing CNS plasmacytoma using intrathecal chemotherapy, radiotherapy, and Daratumumab. Clin Case Rep. 6(4):723-8, 2018
Shpilberg KA et al: Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement. Clin Imaging. 39(2):213-9, 2015
Abdallah AO et al: Patterns of central nervous system involvement in relapsed and refractory multiple myeloma. Clin Lymphoma Myeloma Leuk. 14(3):211-4, 2014
Wu W et al: Extraosseous plasmacytoma with an aggressive course occurring solely in the CNS. Neuropathology. 33(3):320-3, 2013
Baur-Melnyk A et al: Multiple myeloma. Semin Musculoskelet Radiol. 13(2):111-9, 2009
Delorme S et al: Imaging in multiple myeloma. Eur J Radiol. 70(3):401-8, 2009
Cerase A et al: Intracranial involvement in plasmacytomas and multiple myeloma: a pictorial essay. Neuroradiology. 50(8):665-74, 2008
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
Solitary = plasmacytoma (PC)
Solitary PC of bone
Extramedullary PC (includes brain/CNS)
Multifocal = multiple myeloma (MM)
Definitions
Clonal B-lymphocyte neoplasm of terminally differentiated plasma cells
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Other Modality Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Oka S et al: Successful treatment with pomalidomide and intrathecal injections for central nervous system plasmacytoma in a patient under haemodialysis. J Clin Pharm Ther. 45(1):221-5, 2020
Elhassadi E et al: Durable treatment response of relapsing CNS plasmacytoma using intrathecal chemotherapy, radiotherapy, and Daratumumab. Clin Case Rep. 6(4):723-8, 2018
Shpilberg KA et al: Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement. Clin Imaging. 39(2):213-9, 2015
Abdallah AO et al: Patterns of central nervous system involvement in relapsed and refractory multiple myeloma. Clin Lymphoma Myeloma Leuk. 14(3):211-4, 2014
Wu W et al: Extraosseous plasmacytoma with an aggressive course occurring solely in the CNS. Neuropathology. 33(3):320-3, 2013
Baur-Melnyk A et al: Multiple myeloma. Semin Musculoskelet Radiol. 13(2):111-9, 2009
Delorme S et al: Imaging in multiple myeloma. Eur J Radiol. 70(3):401-8, 2009
Cerase A et al: Intracranial involvement in plasmacytomas and multiple myeloma: a pictorial essay. Neuroradiology. 50(8):665-74, 2008
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