Myoepithelial lesion: Rare benign or malignant neoplasm arising from dominant or pure proliferation of myoepithelial cells
Adenomyoepithelioma (AME): Most common, also contains glandular (epithelial) elements
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Torous VF et al: Benign breast lesions that mimic malignancy. Pathology. 49(2):181-196, 2017
Moritz AW et al: Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: A case series emphasizing histologic, radiologic, and clinical correlation. Breast. 29:132-9, 2016
Zhang L et al: The mammography and MRI manifestations of adenomyoepithelioma of the breast. Clin Radiol. 71(3):235-43, 2016
Leekha N et al: Pleomorphic adenoma of breast-a case report and review of literature. Indian J Surg Oncol. 5(2):152-4, 2014
Park YM et al: Imaging features of benign adenomyoepithelioma of the breast. J Clin Ultrasound. 41(4):218-23, 2013
Lakhani SR, Ellis IO, Schnitt SJ, et al. WHO classification of tumours of the breast. Lyon: IARC, 2012
Adejolu M et al: Adenomyoepithelial tumors of the breast: imaging findings with histopathologic correlation. AJR Am J Roentgenol. 197(1):W184-90, 2011
Lee JH et al: Ultrasonographic features of benign adenomyoepithelioma of the breast. Korean J Radiol. 11(5):522-7, 2010
Fan F et al: Myoepithelial carcinoma of the breast arising in an adenomyoepithelioma: mammographic, ultrasound and histologic features. Breast J. 13(2):203-4, 2007
Mercado CL et al: Fine-needle aspiration biopsy of benign adenomyoepithelioma of the breast: radiologic and pathologic correlation in four cases. Diagn Cytopathol. 35(11):690-4, 2007
Ruiz-Delgado ML et al: Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. Acta Radiol. 48(1):27-9, 2007
Nadelman CM et al: "Benign," metastasizing adenomyoepithelioma of the breast: a report of 2 cases. Arch Pathol Lab Med. 130(9):1349-53, 2006
Howlett DC et al: Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology. AJR Am J Roentgenol. 180(3):799-803, 2003
Doyle AJ et al: Myoepithelial lesions of the breast: imaging characteristics and diagnosis with large-core needle biopsy in two cases. Radiology. 193(3):787-8, 1994
Tavassoli FA: Myoepithelial lesions of the breast. Myoepitheliosis, adenomyoepithelioma, and myoepithelial carcinoma. Am J Surg Pathol. 15(6):554-68, 1991
Ballance WA et al: Pleomorphic adenoma (benign mixed tumor) of the breast. An immunohistochemical, flow cytometric, and ultrastructural study and review of the literature. Am J Clin Pathol. 93(6):795-801, 1990
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Myoepithelial lesion: Rare benign or malignant neoplasm arising from dominant or pure proliferation of myoepithelial cells
Adenomyoepithelioma (AME): Most common, also contains glandular (epithelial) elements
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Torous VF et al: Benign breast lesions that mimic malignancy. Pathology. 49(2):181-196, 2017
Moritz AW et al: Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: A case series emphasizing histologic, radiologic, and clinical correlation. Breast. 29:132-9, 2016
Zhang L et al: The mammography and MRI manifestations of adenomyoepithelioma of the breast. Clin Radiol. 71(3):235-43, 2016
Leekha N et al: Pleomorphic adenoma of breast-a case report and review of literature. Indian J Surg Oncol. 5(2):152-4, 2014
Park YM et al: Imaging features of benign adenomyoepithelioma of the breast. J Clin Ultrasound. 41(4):218-23, 2013
Lakhani SR, Ellis IO, Schnitt SJ, et al. WHO classification of tumours of the breast. Lyon: IARC, 2012
Adejolu M et al: Adenomyoepithelial tumors of the breast: imaging findings with histopathologic correlation. AJR Am J Roentgenol. 197(1):W184-90, 2011
Lee JH et al: Ultrasonographic features of benign adenomyoepithelioma of the breast. Korean J Radiol. 11(5):522-7, 2010
Fan F et al: Myoepithelial carcinoma of the breast arising in an adenomyoepithelioma: mammographic, ultrasound and histologic features. Breast J. 13(2):203-4, 2007
Mercado CL et al: Fine-needle aspiration biopsy of benign adenomyoepithelioma of the breast: radiologic and pathologic correlation in four cases. Diagn Cytopathol. 35(11):690-4, 2007
Ruiz-Delgado ML et al: Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. Acta Radiol. 48(1):27-9, 2007
Nadelman CM et al: "Benign," metastasizing adenomyoepithelioma of the breast: a report of 2 cases. Arch Pathol Lab Med. 130(9):1349-53, 2006
Howlett DC et al: Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology. AJR Am J Roentgenol. 180(3):799-803, 2003
Doyle AJ et al: Myoepithelial lesions of the breast: imaging characteristics and diagnosis with large-core needle biopsy in two cases. Radiology. 193(3):787-8, 1994
Tavassoli FA: Myoepithelial lesions of the breast. Myoepitheliosis, adenomyoepithelioma, and myoepithelial carcinoma. Am J Surg Pathol. 15(6):554-68, 1991
Ballance WA et al: Pleomorphic adenoma (benign mixed tumor) of the breast. An immunohistochemical, flow cytometric, and ultrastructural study and review of the literature. Am J Clin Pathol. 93(6):795-801, 1990
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