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Breast
Histopathologic Diagnoses
Locally Aggressive Lesions
Myofibroblastoma
Myofibroblastoma
Nicole S. Winkler, MD; Wendie A. Berg, MD, PhD, FACR, FSBI
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Benign spindle cell tumor with myofibroblastic differentiation

            • Definitions

              • Benign mesenchymal breast tumor composed of fibroblasts and myofibroblasts

            IMAGING

            • General Features

              • Mammographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          Selected References

                                          1. Lee EJ et al: Multimodality images of myofibroblastoma in the male breast: A case report and a review of the literature. Clin Imaging. 51:300-306, 2018
                                          2. Yilmaz R et al: Myofibroblastoma of the breast: Ultrasonography, mammography, and magnetic resonance imaging features with pathologic correlation. Ultrasound Q. 34(2):99-102, 2018
                                          3. Comer JD et al: Myofibroblastoma of the male breast: a rare entity with radiologic-pathologic correlation. Clin Imaging. 42:109-112, 2017
                                          4. El Amine O et al: Myofibroblastoma of the breast: Report of an exceptional case occurring in a young girl. Tunis Med. 94(4):336-337, 2016
                                          5. Metry M et al: Myofibroblastoma of the breast: Literature review and case report. Case Rep Oncol Med. 2016:1714382, 2016
                                          6. Salemis NS et al: Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: management and review of the literature. Breast Dis. 34(1):29-34, 2012
                                          7. Lakhani SR et al. WHO classification of tumours of the breast. Lyon: IARC, 2012
                                          8. Santamaria G et al: Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 30:533-48, 2010
                                          9. Magro G: Mammary myofibroblastoma. Arch Pathol Lab Med 2008;132(11):1813-1820.
                                          10. Vourtsis A et al: Male breast myofibroblastoma and MR findings. J Comput Assist Tomogr. 23(3):414-6, 1999
                                          11. Greenberg JS et al: Myofibroblastoma of the breast in women: imaging appearances. AJR Am J Roentgenol. 171(1):71-2, 1998
                                          12. Miller JA et al: Imaging characteristics of giant myofibroblastoma of the breast diagnosed by ultrasound-guided core biopsy. J Clin Ultrasound. 25(7):395-7, 1997
                                          13. Kobayashi N et al: Myofibroblastoma of the breast: report of a case. Surg Today. 26(9):727-9, 1996
                                          14. Wargotz ES et al Myofibroblastoma of the breast. Sixteen cases of a benign mesenchymal tumor.Am J Surg Pathol 1987;11(7):493-502.
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Benign spindle cell tumor with myofibroblastic differentiation

                                                    • Definitions

                                                      • Benign mesenchymal breast tumor composed of fibroblasts and myofibroblasts

                                                    IMAGING

                                                    • General Features

                                                      • Mammographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  Selected References

                                                                                  1. Lee EJ et al: Multimodality images of myofibroblastoma in the male breast: A case report and a review of the literature. Clin Imaging. 51:300-306, 2018
                                                                                  2. Yilmaz R et al: Myofibroblastoma of the breast: Ultrasonography, mammography, and magnetic resonance imaging features with pathologic correlation. Ultrasound Q. 34(2):99-102, 2018
                                                                                  3. Comer JD et al: Myofibroblastoma of the male breast: a rare entity with radiologic-pathologic correlation. Clin Imaging. 42:109-112, 2017
                                                                                  4. El Amine O et al: Myofibroblastoma of the breast: Report of an exceptional case occurring in a young girl. Tunis Med. 94(4):336-337, 2016
                                                                                  5. Metry M et al: Myofibroblastoma of the breast: Literature review and case report. Case Rep Oncol Med. 2016:1714382, 2016
                                                                                  6. Salemis NS et al: Rapidly growing myofibroblastoma of the breast diagnosed in a premenopausal woman: management and review of the literature. Breast Dis. 34(1):29-34, 2012
                                                                                  7. Lakhani SR et al. WHO classification of tumours of the breast. Lyon: IARC, 2012
                                                                                  8. Santamaria G et al: Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 30:533-48, 2010
                                                                                  9. Magro G: Mammary myofibroblastoma. Arch Pathol Lab Med 2008;132(11):1813-1820.
                                                                                  10. Vourtsis A et al: Male breast myofibroblastoma and MR findings. J Comput Assist Tomogr. 23(3):414-6, 1999
                                                                                  11. Greenberg JS et al: Myofibroblastoma of the breast in women: imaging appearances. AJR Am J Roentgenol. 171(1):71-2, 1998
                                                                                  12. Miller JA et al: Imaging characteristics of giant myofibroblastoma of the breast diagnosed by ultrasound-guided core biopsy. J Clin Ultrasound. 25(7):395-7, 1997
                                                                                  13. Kobayashi N et al: Myofibroblastoma of the breast: report of a case. Surg Today. 26(9):727-9, 1996
                                                                                  14. Wargotz ES et al Myofibroblastoma of the breast. Sixteen cases of a benign mesenchymal tumor.Am J Surg Pathol 1987;11(7):493-502.