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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Round cell liposarcoma
Definitions
- Malignant tumor composed of uniform, round to oval cells with variable numbers of small lipoblasts, set in myxoid stroma with branching capillary vasculature
- Also includes more cellular, high-grade tumors formerly known as round cell liposarcoma
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Lansu J et al: A moderate dose of preoperative radiotherapy may improve resectability in myxoid liposarcoma. Eur J Surg Oncol. 47(10):2633-9, 2021
- Saifuddin A et al: Magnetic resonance imaging of trunk and extremity myxoid liposarcoma: diagnosis, staging, and response to treatment. Skeletal Radiol. 50(10):1963-80, 2021
- Thway K et al: Myxoid liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 42-4, 2020
- Wortman JR et al: Neoadjuvant radiation in primary extremity liposarcoma: correlation of MRI features with histopathology. Eur Radiol. 26(5):1226-34, 2015
- Mankin HJ et al: Liposarcoma: a soft tissue tumor with many presentations. Musculoskelet Surg. 98(3):171-7, 2014
- Petscavage-Thomas JM et al: Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 34(4):964-80, 2014
- Kransdorf MJ et al: Lipomatous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 156-70, 2014
- Walker E et al: Dilemmas in distinguishing between tumor and the posttraumatic lesion with surgical or pathologic correlation. Clin Sports Med. 32(3):559-76, 2013
- Walker EA et al: Magnetic resonance imaging of malignant soft tissue neoplasms in the adult. Radiol Clin North Am. 49(6):1219-34, vi, 2011
- Walker EA et al: Magnetic resonance imaging of soft-tissue masses. Semin Roentgenol. 45(4):277-97, 2010
- Craig WD et al: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 29(1):261-90, 2009
- Sheah K et al: Metastatic myxoid liposarcomas: imaging and histopathologic findings. Skeletal Radiol. 37(3):251-8, 2008
- Weiss SW et al: Liposarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 498-509, 2008
- Murphey MD et al: From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. Radiographics. 25(5):1371-95, 2005
- Antonescu et al: Myxoid liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 40-3, 2002
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Round cell liposarcoma
Definitions
- Malignant tumor composed of uniform, round to oval cells with variable numbers of small lipoblasts, set in myxoid stroma with branching capillary vasculature
- Also includes more cellular, high-grade tumors formerly known as round cell liposarcoma
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Lansu J et al: A moderate dose of preoperative radiotherapy may improve resectability in myxoid liposarcoma. Eur J Surg Oncol. 47(10):2633-9, 2021
- Saifuddin A et al: Magnetic resonance imaging of trunk and extremity myxoid liposarcoma: diagnosis, staging, and response to treatment. Skeletal Radiol. 50(10):1963-80, 2021
- Thway K et al: Myxoid liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 42-4, 2020
- Wortman JR et al: Neoadjuvant radiation in primary extremity liposarcoma: correlation of MRI features with histopathology. Eur Radiol. 26(5):1226-34, 2015
- Mankin HJ et al: Liposarcoma: a soft tissue tumor with many presentations. Musculoskelet Surg. 98(3):171-7, 2014
- Petscavage-Thomas JM et al: Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 34(4):964-80, 2014
- Kransdorf MJ et al: Lipomatous tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 156-70, 2014
- Walker E et al: Dilemmas in distinguishing between tumor and the posttraumatic lesion with surgical or pathologic correlation. Clin Sports Med. 32(3):559-76, 2013
- Walker EA et al: Magnetic resonance imaging of malignant soft tissue neoplasms in the adult. Radiol Clin North Am. 49(6):1219-34, vi, 2011
- Walker EA et al: Magnetic resonance imaging of soft-tissue masses. Semin Roentgenol. 45(4):277-97, 2010
- Craig WD et al: Fat-containing lesions of the retroperitoneum: radiologic-pathologic correlation. Radiographics. 29(1):261-90, 2009
- Sheah K et al: Metastatic myxoid liposarcomas: imaging and histopathologic findings. Skeletal Radiol. 37(3):251-8, 2008
- Weiss SW et al: Liposarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 498-509, 2008
- Murphey MD et al: From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. Radiographics. 25(5):1371-95, 2005
- Antonescu et al: Myxoid liposarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 40-3, 2002
