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Myxoma
Stephanie A. Bernard, MD; B. J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Imaging

    • Pathology

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Definitions

            • Benign tumor of uncertain differentiation (WHO classification) with prominent myxoid stroma

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Angiographic Findings

                        • Nuclear Medicine Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Majoor BCJ et al: Prevalence and clinical features of Mazabraud syndrome: a multicenter European study. J Bone Joint Surg Am. 101(2):160-8, 2019
                                            2. Baheti AD et al: Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 204(2):374-85, 2015
                                            3. Petscavage-Thomas JM et al: Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 34(4):964-80, 2014
                                            4. Yamashita H et al: Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. Skeletal Radiol. 42(10):1475-9, 2013
                                            5. Weiss SW et al: Benign soft tissue tumors and pseudotumors of uncertain type. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 1066-75, 2008
                                            6. Girish G et al: Sonography of intramuscular myxomas: the bright rim and bright cap signs. J Ultrasound Med. 25(7):865-9; quiz 870-1, 2006
                                            7. Harish S et al: Soft tissue masses with "cyst-like" appearance on MR imaging: distinction of benign and malignant lesions. Eur Radiol. 16(12):2652-60, 2006
                                            8. Kransdorf MJ et al: Tumors of uncertain histogenesis. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 485-8, 2006
                                            9. Bancroft LW et al: Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol. 178(5):1255-9, 2002
                                            10. Murphey MD et al: Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 225(1):215-24, 2002
                                            11. Nielsen G et al: Intramuscular myxoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 186-7, 2002
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Imaging

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Benign tumor of uncertain differentiation (WHO classification) with prominent myxoid stroma

                                                    IMAGING

                                                    • General Features

                                                      • Imaging Recommendations

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Angiographic Findings

                                                                  • Nuclear Medicine Findings

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Majoor BCJ et al: Prevalence and clinical features of Mazabraud syndrome: a multicenter European study. J Bone Joint Surg Am. 101(2):160-8, 2019
                                                                                      2. Baheti AD et al: Myxoid soft-tissue neoplasms: comprehensive update of the taxonomy and MRI features. AJR Am J Roentgenol. 204(2):374-85, 2015
                                                                                      3. Petscavage-Thomas JM et al: Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 34(4):964-80, 2014
                                                                                      4. Yamashita H et al: Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. Skeletal Radiol. 42(10):1475-9, 2013
                                                                                      5. Weiss SW et al: Benign soft tissue tumors and pseudotumors of uncertain type. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 1066-75, 2008
                                                                                      6. Girish G et al: Sonography of intramuscular myxomas: the bright rim and bright cap signs. J Ultrasound Med. 25(7):865-9; quiz 870-1, 2006
                                                                                      7. Harish S et al: Soft tissue masses with "cyst-like" appearance on MR imaging: distinction of benign and malignant lesions. Eur Radiol. 16(12):2652-60, 2006
                                                                                      8. Kransdorf MJ et al: Tumors of uncertain histogenesis. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 485-8, 2006
                                                                                      9. Bancroft LW et al: Intramuscular myxoma: characteristic MR imaging features. AJR Am J Roentgenol. 178(5):1255-9, 2002
                                                                                      10. Murphey MD et al: Imaging of soft-tissue myxoma with emphasis on CT and MR and comparison of radiologic and pathologic findings. Radiology. 225(1):215-24, 2002
                                                                                      11. Nielsen G et al: Intramuscular myxoma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 186-7, 2002