Destruction of osteocartilaginous structures of nose, sinuses, and palate induced by chronic inhalation of cocaine
IMAGING
General Features
Imaging Recommendations
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Mirzaei A et al: Differentiation of cocaine-induced midline destructive lesions from ANCA-associated vasculitis. Iran J Otorhinolaryngol. 30(100):309-13, 2018
Brembilla C et al: Craniovertebral junction instability as an extension of cocaine-induced midline destructive lesions: case report. J Neurosurg Spine. 23(2):159-65, 2015
Laudien M: Orphan diseases of the nose and paranasal sinuses: Pathogenesis - clinic - therapy. GMS Curr Top Otorhinolaryngol Head Neck Surg. 14:Doc 04, 2015
D'Amico M et al: An observational study of nasal cavity toxicity in cancer patients treated with bevacizumab. Expert Opin Drug Saf. 13(11):1437-42, 2014
Lawrence LA et al: Levamisole-adulterated cocaine induced skin necrosis of nose, ears, and extremities: Case report. Allergy Rhinol (Providence). 5(3):132-6, 2014
Trimarchi M et al: Cocaine induced midline destructive lesions. Rhinology. 52(2):104-11, 2014
Albert L Jr et al: Cocaine-induced encephalocele: case report and literature review. Neurosurgery. 68(1):E263-6, 2011
Businco LD et al: Psychological aspects and treatment of patients with nasal septal perforation due to cocaine inhalation. Acta Otorhinolaryngol Ital. 28(5):247-51, 2008
Valencia MP et al: Congenital and acquired lesions of the nasal septum: a practical guide for differential diagnosis. Radiographics. 28(1):205-24; quiz 326, 2008
Di Cosola M et al: Cocaine-related syndrome and palatal reconstruction: report of a series of cases. Int J Oral Maxillofac Surg. 36(8):721-7, 2007
Westreich RW et al: Midline necrotizing nasal lesions: analysis of 18 cases emphasizing radiological and serological findings with algorithms for diagnosis and management. Am J Rhinol. 18(4):209-19, 2004
Trimarchi M et al: Sinonasal osteocartilaginous necrosis in cocaine abusers: experience in 25 patients. Am J Rhinol. 17(1):33-43, 2003
Armstrong M Jr et al: Nasal septal necrosis mimicking Wegener's granulomatosis in a cocaine abuser. Ear Nose Throat J. 75(9):623-6, 1996
Allbery SM et al: MR imaging of nasal masses. Radiographics. 15(6):1311-27, 1995
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Nasal cocaine necrosis (NCN)
Synonyms
Cocaine-induced midline destructive lesions
Definitions
Destruction of osteocartilaginous structures of nose, sinuses, and palate induced by chronic inhalation of cocaine
IMAGING
General Features
Imaging Recommendations
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Mirzaei A et al: Differentiation of cocaine-induced midline destructive lesions from ANCA-associated vasculitis. Iran J Otorhinolaryngol. 30(100):309-13, 2018
Brembilla C et al: Craniovertebral junction instability as an extension of cocaine-induced midline destructive lesions: case report. J Neurosurg Spine. 23(2):159-65, 2015
Laudien M: Orphan diseases of the nose and paranasal sinuses: Pathogenesis - clinic - therapy. GMS Curr Top Otorhinolaryngol Head Neck Surg. 14:Doc 04, 2015
D'Amico M et al: An observational study of nasal cavity toxicity in cancer patients treated with bevacizumab. Expert Opin Drug Saf. 13(11):1437-42, 2014
Lawrence LA et al: Levamisole-adulterated cocaine induced skin necrosis of nose, ears, and extremities: Case report. Allergy Rhinol (Providence). 5(3):132-6, 2014
Trimarchi M et al: Cocaine induced midline destructive lesions. Rhinology. 52(2):104-11, 2014
Albert L Jr et al: Cocaine-induced encephalocele: case report and literature review. Neurosurgery. 68(1):E263-6, 2011
Businco LD et al: Psychological aspects and treatment of patients with nasal septal perforation due to cocaine inhalation. Acta Otorhinolaryngol Ital. 28(5):247-51, 2008
Valencia MP et al: Congenital and acquired lesions of the nasal septum: a practical guide for differential diagnosis. Radiographics. 28(1):205-24; quiz 326, 2008
Di Cosola M et al: Cocaine-related syndrome and palatal reconstruction: report of a series of cases. Int J Oral Maxillofac Surg. 36(8):721-7, 2007
Westreich RW et al: Midline necrotizing nasal lesions: analysis of 18 cases emphasizing radiological and serological findings with algorithms for diagnosis and management. Am J Rhinol. 18(4):209-19, 2004
Trimarchi M et al: Sinonasal osteocartilaginous necrosis in cocaine abusers: experience in 25 patients. Am J Rhinol. 17(1):33-43, 2003
Armstrong M Jr et al: Nasal septal necrosis mimicking Wegener's granulomatosis in a cocaine abuser. Ear Nose Throat J. 75(9):623-6, 1996
Allbery SM et al: MR imaging of nasal masses. Radiographics. 15(6):1311-27, 1995
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