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Cardiac
Diagnosis
Pericardial
Neoplastic Pericardial Involvement
Neoplastic Pericardial Involvement
John P. Lichtenberger, III, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Pericardial involvement with primary or secondary neoplasm
                • Most frequently metastatic via direct invasion, lymphatic spread, or hemorrhagic spread

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Echocardiographic Findings

                      • Angiographic Findings

                        • Nuclear Medicine Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Kligerman S: Imaging of Pericardial Disease. Radiol Clin North Am. 57(1):179-199, 2019
                                              2. Cummings KW et al: Imaging of pericardial diseases. Semin Ultrasound CT MR. 37(3):238-54, 2016
                                              3. Bogaert J et al: Pericardial disease: Value of CT and MR imaging. Radiology. 267(2):340-56, 2013
                                              4. Makis W et al: Spectrum of malignant pleural and pericardial disease on FDG PET/CT. AJR Am J Roentgenol. 198(3):678-85, 2012
                                              5. Prakash P et al: Imaging findings of pericardial metastasis on chest computed tomography. J Comput Assist Tomogr. 34(4):554-8, 2010
                                              6. Little WC et al: Pericardial disease. Circulation. 113(12):1622-32, 2006
                                              7. Abbara S et al: Pericardial and myocardial disease. In Miller SW: Cardiac Imaging: The Requisites. Philadelphia: Elsevier Mosby. 245-283, 2005
                                              8. Bernhardt P et al: Cardiac magnetic resonance in outpatients in Germany-indications, complications and protocol suggestions from a high-volume center. Int J Cardiol. 2005
                                              9. Imazio M et al: Relation of acute pericardial disease to malignancy. Am J Cardiol. 95(11):1393-4, 2005
                                              10. Sagrista-Sauleda J et al: Effusive-constrictive pericarditis. N Engl J Med. 350(5):469-75, 2004
                                              11. Troughton RW et al: Pericarditis. Lancet. 363(9410):717-27, 2004
                                              12. Warren WH: Malignancies involving the pericardium. Semin Thorac Cardiovasc Surg. 12(2):119-29, 2000
                                              13. Spodick DH: Neoplastic pericardial disease. In Spodick DH: The Pericardium: A Comprehensive Textbook. New York: Marcel Dekker. 301-13, 1997
                                              14. Cameron J et al: The etiologic spectrum of constrictive pericarditis. Am Heart J. 113(2 Pt 1):354-60, 1987
                                              15. Mann T et al: Effusive-constrictive hemodynamic pattern due to neoplastic involvement of the pericardium. Am J Cardiol. 41(4):781-6, 1978
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Pericardial involvement with primary or secondary neoplasm
                                                            • Most frequently metastatic via direct invasion, lymphatic spread, or hemorrhagic spread

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Echocardiographic Findings

                                                                  • Angiographic Findings

                                                                    • Nuclear Medicine Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Kligerman S: Imaging of Pericardial Disease. Radiol Clin North Am. 57(1):179-199, 2019
                                                                                          2. Cummings KW et al: Imaging of pericardial diseases. Semin Ultrasound CT MR. 37(3):238-54, 2016
                                                                                          3. Bogaert J et al: Pericardial disease: Value of CT and MR imaging. Radiology. 267(2):340-56, 2013
                                                                                          4. Makis W et al: Spectrum of malignant pleural and pericardial disease on FDG PET/CT. AJR Am J Roentgenol. 198(3):678-85, 2012
                                                                                          5. Prakash P et al: Imaging findings of pericardial metastasis on chest computed tomography. J Comput Assist Tomogr. 34(4):554-8, 2010
                                                                                          6. Little WC et al: Pericardial disease. Circulation. 113(12):1622-32, 2006
                                                                                          7. Abbara S et al: Pericardial and myocardial disease. In Miller SW: Cardiac Imaging: The Requisites. Philadelphia: Elsevier Mosby. 245-283, 2005
                                                                                          8. Bernhardt P et al: Cardiac magnetic resonance in outpatients in Germany-indications, complications and protocol suggestions from a high-volume center. Int J Cardiol. 2005
                                                                                          9. Imazio M et al: Relation of acute pericardial disease to malignancy. Am J Cardiol. 95(11):1393-4, 2005
                                                                                          10. Sagrista-Sauleda J et al: Effusive-constrictive pericarditis. N Engl J Med. 350(5):469-75, 2004
                                                                                          11. Troughton RW et al: Pericarditis. Lancet. 363(9410):717-27, 2004
                                                                                          12. Warren WH: Malignancies involving the pericardium. Semin Thorac Cardiovasc Surg. 12(2):119-29, 2000
                                                                                          13. Spodick DH: Neoplastic pericardial disease. In Spodick DH: The Pericardium: A Comprehensive Textbook. New York: Marcel Dekker. 301-13, 1997
                                                                                          14. Cameron J et al: The etiologic spectrum of constrictive pericarditis. Am Heart J. 113(2 Pt 1):354-60, 1987
                                                                                          15. Mann T et al: Effusive-constrictive hemodynamic pattern due to neoplastic involvement of the pericardium. Am J Cardiol. 41(4):781-6, 1978