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Nephrocalcinosis
Kevin Kalisz, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Medullary nephrocalcinosis, cortical nephrocalcinosis
              • Definitions

                • Medullary nephrocalcinosis: Deposition of calcium within medullary portions of kidney
                • Cortical nephrocalcinosis: Deposition of calcium within cortical portions of kidney

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        • MR Findings

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              • Reporting Tips

                                                Selected References

                                                1. Feehally J: Comprehensive Clinical Nephrology. Elsevier, 2019
                                                2. Fogo AB et al: AJKD atlas of renal pathology: nephrocalcinosis and acute phosphate nephropathy. Am J Kidney Dis. 69(3):e17-18, 2017
                                                3. Koraishy FM et al: CT urography for the diagnosis of medullary sponge kidney. Am J Nephrol. 39(2):165-70, 2014
                                                4. Boyce AM et al: Ultrasound is superior to computed tomography for assessment of medullary nephrocalcinosis in hypoparathyroidism. J Clin Endocrinol Metab. 98(3):989-94, 2013
                                                5. Cheidde L et al: A critical appraisal of the radiological evaluation of nephrocalcinosis. Nephron Clin Pract. 106(3):c119-24, 2007
                                                6. Jung DC et al: Renal papillary necrosis: review and comparison of findings at multi-detector row CT and intravenous urography. Radiographics. 26(6):1827-36, 2006
                                                7. Gibson MS et al: Renal tuberculosis. Radiographics. 24(1):251-6, 2004
                                                8. Dyer RB et al: Abnormal calcifications in the urinary tract. Radiographics. 18(6):1405-24, 1998
                                                9. Riehl J et al: Medullary nephrocalcinosis: sonographic findings in adult patients. Bildgebung. 62(1):18-22, 1995
                                                10. Lloyd HM: Primary hyperparathyroidism: an analysis of the role of the parathyroid tumor. Medicine (Baltimore). 47(1):53-71, 1968
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Synonyms

                                                              • Medullary nephrocalcinosis, cortical nephrocalcinosis
                                                            • Definitions

                                                              • Medullary nephrocalcinosis: Deposition of calcium within medullary portions of kidney
                                                              • Cortical nephrocalcinosis: Deposition of calcium within cortical portions of kidney

                                                            IMAGING

                                                            • General Features

                                                              • Radiographic Findings

                                                                • CT Findings

                                                                  • Ultrasonographic Findings

                                                                    • Imaging Recommendations

                                                                      • MR Findings

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          • Image Interpretation Pearls

                                                                                            • Reporting Tips

                                                                                              Selected References

                                                                                              1. Feehally J: Comprehensive Clinical Nephrology. Elsevier, 2019
                                                                                              2. Fogo AB et al: AJKD atlas of renal pathology: nephrocalcinosis and acute phosphate nephropathy. Am J Kidney Dis. 69(3):e17-18, 2017
                                                                                              3. Koraishy FM et al: CT urography for the diagnosis of medullary sponge kidney. Am J Nephrol. 39(2):165-70, 2014
                                                                                              4. Boyce AM et al: Ultrasound is superior to computed tomography for assessment of medullary nephrocalcinosis in hypoparathyroidism. J Clin Endocrinol Metab. 98(3):989-94, 2013
                                                                                              5. Cheidde L et al: A critical appraisal of the radiological evaluation of nephrocalcinosis. Nephron Clin Pract. 106(3):c119-24, 2007
                                                                                              6. Jung DC et al: Renal papillary necrosis: review and comparison of findings at multi-detector row CT and intravenous urography. Radiographics. 26(6):1827-36, 2006
                                                                                              7. Gibson MS et al: Renal tuberculosis. Radiographics. 24(1):251-6, 2004
                                                                                              8. Dyer RB et al: Abnormal calcifications in the urinary tract. Radiographics. 18(6):1405-24, 1998
                                                                                              9. Riehl J et al: Medullary nephrocalcinosis: sonographic findings in adult patients. Bildgebung. 62(1):18-22, 1995
                                                                                              10. Lloyd HM: Primary hyperparathyroidism: an analysis of the role of the parathyroid tumor. Medicine (Baltimore). 47(1):53-71, 1968