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Neurocysticercosis
Miral D. Jhaveri, MD; Karen L. Salzman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Neurocysticercosis (NCC)
          • Synonyms

            • Cysticercosis
          • Definitions

            • Intracranial parasitic infection caused by pork tapeworm Taenia solium
              • 4 pathologic stages: Vesicular, colloidal vesicular, granular nodular, and nodular calcified

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Del Brutto OH: Neurocysticercosis. Handb Clin Neurol. 121:1445-59, 2014
                                        2. Hernández RD et al: Magnetic resonance imaging in neurocysticercosis. Top Magn Reson Imaging. 23(3):191-8, 2014
                                        3. Bhattacharjee S et al: Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: A study from Eastern India. Ann Indian Acad Neurol. 16(4):549-55, 2013
                                        4. Carpio A et al: Neurocysticercosis: Five new things. Neurol Clin Pract. 3(2):118-125, 2013
                                        5. Cuello-García CA et al: Corticosteroids for neurocysticercosis: a systematic review and meta-analysis of randomized controlled trials. Int J Infect Dis. 17(8):e583-92, 2013
                                        6. Souza Ad et al: Solitary cerebral parenchymal cysticercosis: a prospective comparative study with computed tomography and magnetic resonance imaging. Neurol India. 61(6):639-43, 2013
                                        7. Lerner A et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 22(4):659-76, 2012
                                        8. Sinha S et al: Intraventricular neurocysticercosis: a review of current status and management issues. Br J Neurosurg. 26(3):305-9, 2012
                                        9. Matushita H et al: Hydrocephalus in neurocysticercosis. Childs Nerv Syst. 27(10):1709-21, 2011
                                        10. Angeles CF et al: Transventricular neuroendoscopic excision of giant racemose subarachnoid cysticercosis. Childs Nerv Syst. 25(4):503-8, 2009
                                        11. Sinha S et al: Neurocysticercosis: a review of current status and management. J Clin Neurosci. 16(7):867-76, 2009
                                        12. Goel RK et al: Endoscopic management of intraventricular neurocysticercosis. J Clin Neurosci. 15(10):1096-101, 2008
                                        13. Jimenez-Vazquez OH et al: Cisternal neurocysticercosis. Br J Neurosurg. 22(6):774-5, 2008
                                        14. Jung H et al: Medical treatment for neurocysticercosis: drugs, indications and perspectives. Curr Top Med Chem. 8(5):424-33, 2008
                                        15. Kraft R: Cysticercosis: an emerging parasitic disease. Am Fam Physician. 2007 Jul 1;76(1):91-6. Review. Erratum in: Am Fam Physician. 77(6):748, 2008
                                        16. Odermatt P et al: Treatment of neurocysticercosis: a randomised controlled trial. J Neurol Neurosurg Psychiatry. 79(9):978, 2008
                                        17. Kwee RM et al: Virchow-Robin spaces at MR imaging. Radiographics. 27(4):1071-86, 2007
                                        18. Lucato LT et al: The role of conventional MR imaging sequences in the evaluation of neurocysticercosis: impact on characterization of the scolex and lesion burden. AJNR Am J Neuroradiol. 28(8):1501-4, 2007
                                        19. Mathews M et al: Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol. 67(6):647-9, 2007
                                        20. Bhigjee AI et al: Optimizing therapy of seizures in patients with HIV and cysticercosis. Neurology. 67(12 Suppl 4):S19-22, 2006
                                        21. Reddy JS et al: The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions. Surg Neurol. 66(3):246-50; discussion 250-1, 2006
                                        22. Sáenz B et al: Neurocysticercosis: clinical, radiologic, and inflammatory differences between children and adults. Pediatr Infect Dis J. 25(9):801-3, 2006
                                        23. Velasco TR et al: Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patients. J Neurol Neurosurg Psychiatry. 77(4):485-8, 2006
                                        24. Jayakumar PN et al: MRI and in vivo proton MR spectroscopy in a racemose cysticercal cyst of the brain. Neuroradiology. 46(1):72-4, 2004
                                        25. Garcia HH et al: Taenia solium cysticercosis. Lancet. 362(9383):547-56, 2003
                                        26. Zee CS et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 10(2):391-407, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Neurocysticercosis (NCC)
                                                • Synonyms

                                                  • Cysticercosis
                                                • Definitions

                                                  • Intracranial parasitic infection caused by pork tapeworm Taenia solium
                                                    • 4 pathologic stages: Vesicular, colloidal vesicular, granular nodular, and nodular calcified

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Del Brutto OH: Neurocysticercosis. Handb Clin Neurol. 121:1445-59, 2014
                                                                              2. Hernández RD et al: Magnetic resonance imaging in neurocysticercosis. Top Magn Reson Imaging. 23(3):191-8, 2014
                                                                              3. Bhattacharjee S et al: Clinical profile and follow-up of 51 pediatric neurocysticercosis cases: A study from Eastern India. Ann Indian Acad Neurol. 16(4):549-55, 2013
                                                                              4. Carpio A et al: Neurocysticercosis: Five new things. Neurol Clin Pract. 3(2):118-125, 2013
                                                                              5. Cuello-García CA et al: Corticosteroids for neurocysticercosis: a systematic review and meta-analysis of randomized controlled trials. Int J Infect Dis. 17(8):e583-92, 2013
                                                                              6. Souza Ad et al: Solitary cerebral parenchymal cysticercosis: a prospective comparative study with computed tomography and magnetic resonance imaging. Neurol India. 61(6):639-43, 2013
                                                                              7. Lerner A et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 22(4):659-76, 2012
                                                                              8. Sinha S et al: Intraventricular neurocysticercosis: a review of current status and management issues. Br J Neurosurg. 26(3):305-9, 2012
                                                                              9. Matushita H et al: Hydrocephalus in neurocysticercosis. Childs Nerv Syst. 27(10):1709-21, 2011
                                                                              10. Angeles CF et al: Transventricular neuroendoscopic excision of giant racemose subarachnoid cysticercosis. Childs Nerv Syst. 25(4):503-8, 2009
                                                                              11. Sinha S et al: Neurocysticercosis: a review of current status and management. J Clin Neurosci. 16(7):867-76, 2009
                                                                              12. Goel RK et al: Endoscopic management of intraventricular neurocysticercosis. J Clin Neurosci. 15(10):1096-101, 2008
                                                                              13. Jimenez-Vazquez OH et al: Cisternal neurocysticercosis. Br J Neurosurg. 22(6):774-5, 2008
                                                                              14. Jung H et al: Medical treatment for neurocysticercosis: drugs, indications and perspectives. Curr Top Med Chem. 8(5):424-33, 2008
                                                                              15. Kraft R: Cysticercosis: an emerging parasitic disease. Am Fam Physician. 2007 Jul 1;76(1):91-6. Review. Erratum in: Am Fam Physician. 77(6):748, 2008
                                                                              16. Odermatt P et al: Treatment of neurocysticercosis: a randomised controlled trial. J Neurol Neurosurg Psychiatry. 79(9):978, 2008
                                                                              17. Kwee RM et al: Virchow-Robin spaces at MR imaging. Radiographics. 27(4):1071-86, 2007
                                                                              18. Lucato LT et al: The role of conventional MR imaging sequences in the evaluation of neurocysticercosis: impact on characterization of the scolex and lesion burden. AJNR Am J Neuroradiol. 28(8):1501-4, 2007
                                                                              19. Mathews M et al: Intraventricular cryptococcal cysts masquerading as racemose neurocysticercosis. Surg Neurol. 67(6):647-9, 2007
                                                                              20. Bhigjee AI et al: Optimizing therapy of seizures in patients with HIV and cysticercosis. Neurology. 67(12 Suppl 4):S19-22, 2006
                                                                              21. Reddy JS et al: The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions. Surg Neurol. 66(3):246-50; discussion 250-1, 2006
                                                                              22. Sáenz B et al: Neurocysticercosis: clinical, radiologic, and inflammatory differences between children and adults. Pediatr Infect Dis J. 25(9):801-3, 2006
                                                                              23. Velasco TR et al: Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patients. J Neurol Neurosurg Psychiatry. 77(4):485-8, 2006
                                                                              24. Jayakumar PN et al: MRI and in vivo proton MR spectroscopy in a racemose cysticercal cyst of the brain. Neuroradiology. 46(1):72-4, 2004
                                                                              25. Garcia HH et al: Taenia solium cysticercosis. Lancet. 362(9383):547-56, 2003
                                                                              26. Zee CS et al: Imaging of neurocysticercosis. Neuroimaging Clin N Am. 10(2):391-407, 2000